Postnatal weight gain and retinopathy of prematurity.

Abstract:

:Infants meeting retinopathy of prematurity (ROP) screening guidelines based on birth weight and gestational age undergo serial examinations by ophthalmologists for detection and treatment. However, less than 10% require treatment, and less than half develop ROP. Slow postnatal weight gain is highly predictive of ROP, and investigators have incorporated weight gain measures to develop more specific criteria for ROP screening. Such clinical prediction model use involves a large development study, validation studies specific to the target populations, and ongoing impact surveillance, with adjustment as necessary. Of the many weight gain inclusive prediction models intended to improve the precision of ROP screening, the Postnatal Growth and ROP (G-ROP) modified screening criteria were developed using the largest dataset and may provide the most robust model for clinical use. A recently completed G-ROP validation study will evaluate the generalizability of these modified criteria prior to clinical use.

journal_name

Semin Perinatol

journal_title

Seminars in perinatology

authors

Lin L,Binenbaum G

doi

10.1053/j.semperi.2019.05.008

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

352-359

issue

6

eissn

0146-0005

issn

1558-075X

pii

S0146-0005(19)30068-0

journal_volume

43

pub_type

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