Cellular and molecular basis of circadian timing in mammals.

abstract：:The safety of cesarean section has improved dramatically over the past 50 years. During the past 20 years a greater awareness of and discussion about the symptomatic morbidity that can result for women following vaginal delivery has occurred and women's expectations for the outcome of pregnancy for them and their babi...

journal_title：Seminars in perinatology

authors： Morrison J,MacKenzie IZ

更新日期：2003-02-01 00:00:00

abstract：:The incidence of twins, triplets, and high-order multiples has increased dramatically in the last two decades secondary to greater reliance on fertility treatments and to delayed childbearing. Offspring of a multiple gestation are at increased risk for both chromosomal and structural abnormalities. Prenatal diagnosis ...

journal_title：Seminars in perinatology

authors： Cleary-Goldman J,D'Alton ME,Berkowitz RL

更新日期：2005-10-01 00:00:00

abstract：:Tumors are a rare but important cause of mortality and morbidity in the neonate. There is a wide spectrum of benign and malignant tumors that can occur, some of which have a unique presentation and behavior in this age group. It is important to recognize that tumors such as stage IVS neuroblastoma, which have a good p...

journal_title：Seminars in perinatology

authors： Weitzman S,Grant R

更新日期：1997-02-01 00:00:00

abstract：:Clinically silent upper genital tract microbial infections have been strongly associated with spontaneous preterm delivery, especially prior to 32 weeks gestational age. This condition represents a potentially preventable or reversible cause of preterm birth using safe, readily available, and inexpensive antibiotics. ...

journal_title：Seminars in perinatology

authors： Andrews WW,Goldenberg RL,National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

更新日期：2003-06-01 00:00:00

abstract：:Obstetric hemorrhage is often a sudden, life-threatening event. Successful management hinges on both preoperative preparation if hemorrhage is anticipated as well as knowledge of interventions. Uterine-sparing techniques, such as aggressive and early use of uterotonics, balloon tamponade, uterine compression sutures, ...

journal_title：Seminars in perinatology

authors： Shah M,Wright JD

更新日期：2009-04-01 00:00:00

abstract：:Among risk factors for shoulder dystocia, a prior history of delivery complicated by shoulder dystocia is the single greatest risk factor for shoulder dystocia occurrence, with odds ratios 7 to 10 times that of the general population. Recurrence rates have been reported to be as high as 16%. Whereas prevention of shou...

journal_title：Seminars in perinatology

authors： Gurewitsch ED,Johnson TL,Allen RH

更新日期：2007-06-01 00:00:00

abstract：:With 50-90% of pregnant women experiencing nausea and vomiting of pregnancy (NVP), the burden of illness can become quite significant if symptoms are under-treated and/or under-diagnosed, thus allowing for progression of the disease. The majority of these women will necessitate at least one visit with a provider to sp...

journal_title：Seminars in perinatology

authors： Clark SM,Dutta E,Hankins GD

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Cardiovascular disease is the major cause of pregnancy-related maternal mortality in the United States, and congenital heart disease (CHD) is the most common form of structural heart disease affecting women of childbearing age. Most females born with CHD will reach childbearing age and consider pregnancy. Adu...

journal_title：Seminars in perinatology

authors： Connolly HM

更新日期：2018-02-01 00:00:00

abstract：:Many perinatal pathogens are able to survive and in some cases replicate intracellularly. With the exception of viruses and toxoplasma, these pathogens principally infect phagocytic cells of the reticuloendothelial system. Such intracellular organisms, by evading the effects of antibiotics that act only extracellularl...

journal_title：Seminars in perinatology

authors： Wilson CB,Jacobs RF,Smith AL

更新日期：1982-04-01 00:00:00

abstract：:The product label required by the FDA for every drug approved for marketing in the US is a legal document that originates with the company that wants to market the drug, but it must be approved by the FDA. Despite the recognized limitations of registries, the FDA's new labeling rule, effective from July 1, 2015, has g...

journal_title：Seminars in perinatology

authors： Greene MF

更新日期：2015-11-01 00:00:00

abstract：:Although a minor constituent by weight, surfactant protein B (SP-B) plays a major role in surfactant function. It is the unique structure of SP-B that promotes permeabilization, cross-linking, mixing, and fusion of phospholipids, facilitating the proper structure and function of pulmonary surfactant as well as contrib...

journal_title：Seminars in perinatology

authors： Guttentag S

更新日期：2008-10-01 00:00:00

abstract：:Newborn screening (NBS) reaches approximately all of the 4 million newborns in the United States each year and has been effective in significantly reducing the morbidity and mortality that results from certain congenital conditions. The comprehensive NBS system can be divided into preanalytic (education and screening)...

journal_title：Seminars in perinatology

authors： Therrell BL Jr,Schwartz M,Southard C,Williams D,Hannon WH,Mann MY,PEAS Organizing and Working Groups.

更新日期：2010-04-01 00:00:00

abstract：:The development of ultrafast magnetic resonance imaging scanners and sequences provides a new tool for the diagnosis of fetal anomalies. Magnetic resonance imaging is a valuable adjunct to prenatal ultrasound especially for the evaluation of suspected fetal brain anomalies, chest masses, abdominal masses, and renal di...

journal_title：Seminars in perinatology

authors： Hubbard AM,Harty MP,States LJ

更新日期：1999-12-01 00:00:00

abstract：:Poorly controlled maternal diabetes in pregnancy may delay fetal pulmonary maturation. However, diabetic women with good glycemic control have fetal lung maturation at the same gestational age as nondiabetic women. With modern ultrasound technology, gestational dates can be accurately assessed in the first or early se...

journal_title：Seminars in perinatology

authors： Piper JM

更新日期：2002-06-01 00:00:00

abstract：:Supplemental oxygen is often used as a life-saving therapy in the treatment of preterm infants. However, its protracted use can lead to the development of bronchopulmonary dysplasia (BPD), and more recently, has been associated with adversely affecting the general health of children and adolescents who were born prete...

journal_title：Seminars in perinatology

authors： Buczynski BW,Maduekwe ET,O'Reilly MA

更新日期：2013-04-01 00:00:00

abstract：:Prenatal diagnosis of fetal aneuploidy is a continuously and rapidly evolving area of research. Currently in the United States, the standard of care for screening pregnancies for aneuploidy involves assessment of maternal age together with the use of multiple second trimester maternal serum markers. This screening app...

journal_title：Seminars in perinatology

authors： Stewart TL,Malone FD

更新日期：1999-10-01 00:00:00

abstract：:Sleep-disordered breathing occurs in 0.6-15% of reproductive age women. This condition is associated with an increased lifetime risk of cardiovascular disease, cardiovascular mortality, and all-cause mortality. A substantial body of evidence demonstrated increased perinatal morbidity among pregnancies affected by SDB ...

journal_title：Seminars in perinatology

authors： Cain MA,Ricciuti J,Louis JM

更新日期：2015-06-01 00:00:00

abstract：:Intrauterine growth restriction (IUGR), which complicates approximately 3% to 10% of all pregnancies leads to preferential hemodynamic changes in affected fetuses. Advanced ultrasound modalities allow reliable and reproducible assessment of the intrauterine fetal cardiac function. Among other methods, combined cardiac...

journal_title：Seminars in perinatology

authors： Bahtiyar MO,Copel JA

更新日期：2008-06-01 00:00:00

abstract：:For many years, all of the described cases of monoamine neurotransmitter deficiency were associated with hyperphenylalaninemia that was generally detected at neonatal screening. It is now clear that inherited deficiency of monoamines often occurs in the absence of hyperphenylalaninemia and that the normal battery of s...

journal_title：Seminars in perinatology

authors： Hyland K

更新日期：1999-04-01 00:00:00

abstract：:The studies described above collectively suggest that, whenever there is a decrease in fluid balance in the fetus, both fetal urine flow and tracheal secretion into the amniotic space are decreased. Conversely, when fetal hydration is increased, both urine and tracheal flows into the amniotic fluid may be increased. T...

journal_title：Seminars in perinatology

authors： Brace RA

更新日期：1986-04-01 00:00:00

abstract：:The renin angiotensin system (RAS) is now recognized as the body's most powerful hormone system for controlling renal hemodynamics and sodium excretion and, therefore, body fluid volumes and arterial pressure. The discovery of angiotensin converting enzyme inhibitors (ACEi) was a keystone for the understanding of the ...

journal_title：Seminars in perinatology

authors： Ferreira SH

更新日期：2000-02-01 00:00:00

abstract：:Neuroblastoma is the most common malignant neoplasm occurring in the neonate and arguably the most variable in its presentation. This review examines differences in the tumor's clinical course in the context of known biologic determinants of behavior. Tumors that would go undetected except for prenatal ultrasonography...

journal_title：Seminars in perinatology

authors： Lukens JN

更新日期：1999-08-01 00:00:00

abstract：:Long-term sequelae of preterm birth have been studied extensively up until the age of 5 to 8 years. However, the cognitive development of adolescents born preterm has received limited attention. The objective of this study is to determine school performance in adolescents born very preterm. We have followed up a cohor...

journal_title：Seminars in perinatology

authors： van de Bor M,den Ouden L

更新日期：2004-08-01 00:00:00

abstract：:This review documents and assesses recent trends in sudden infant death syndrome. We review medical literature, Internet resources, and national governmental data. A striking reduction in SIDS incidence of more than 50% has been observed in various countries after interventions, particularly during the early 1990s, to...

journal_title：Seminars in perinatology

authors： Ponsonby AL,Dwyer T,Cochrane J

更新日期：2002-08-01 00:00:00

abstract：:Understanding the role of ion channels in the generation of slow waves and action potentials in the myometrium is critical in designing strategies to regulate uterine contractile activity. The development of the patch clamp technique has allowed the identification of specific types of channels in the myometrium and pr...

journal_title：Seminars in perinatology

authors： Sanborn BM

更新日期：1995-02-01 00:00:00

abstract：:Fetal and neonatal alloimmune thrombocytopenia is not a well-known disease, except among specialists in maternal-fetal medicine, neonatologists, and certain pediatricians (ie, hematologists). However, this is by far the most common cause of early severe thrombocytopenia in neonates and of intracranial hemorrhage in te...

journal_title：Seminars in perinatology

authors： Bussel JB,Sola-Visner M

更新日期：2009-02-01 00:00:00

abstract：:Accurate assessment of fetal growth status requires the definition of an optimal standard, which represents the growth potential of the baby. Against this standard, individually 'customized' percentiles can be calculated. They improve the distinction between normal and abnormal, and help in our understanding and diagn...

journal_title：Seminars in perinatology

authors： Gardosi J

更新日期：2004-02-01 00:00:00

abstract：:Up to half of all aortic dissections and ruptures in women younger than 40 years are associated with pregnancy. In pregnancy, women with aortic disease such as arteritis and aortitis are at significant risk of aneurysmal formation and dissection with potential for catastrophic outcomes. Pregnancy places predisposed wo...

journal_title：Seminars in perinatology

authors： Smok DA

更新日期：2014-08-01 00:00:00

abstract：:Multiple gestation carries a significant risk of perinatal complications and mortality. Often twin neonates are delivered small and early with a perinatal mortality rate five to seven times that of singleton neonates. Increased morbidity and mortality is due to an increased incidence of antepartum complications, monoz...

journal_title：Seminars in perinatology

authors： Newton ER

更新日期：1986-01-01 00:00:00

abstract：:Neonatal hyperinsulinism (HI) is a clinical syndrome of pancreatic beta-cell dysfunction characterized by failure to suppress insulin secretion in the presence of hypoglycemia. Although rare, it is the most common cause for persistent hypoglycemia in the newborn period. Treatment can be extremely difficult, and partia...

journal_title：Seminars in perinatology

authors： Glaser B

更新日期：2000-04-01 00:00:00