Current approaches to the evaluation and management of the fetus and neonate with immune thrombocytopenia.

abstract：:There have been no controlled studies that clearly document a beneficial effect of TPN on neonatal mortality and morbidity. Beneficial effects such as reducing the time required to achieve some targeted weight and enhancing positive nitrogen balance are used in support of TPN. The positive opinion about TPN is strongl...

journal_title：Seminars in perinatology

authors： Gutcher G,Cutz E

更新日期：1986-07-01 00:00:00

abstract：:The importance of omega-3 long chain polyunsaturated fatty acids in the perinatal period has been the focus of research for several decades. Infants born preterm miss out on the last trimester in utero transfer of omega-3 fatty acids and consequently have lower blood levels than infants born at term. Preterm infant fo...

journal_title：Seminars in perinatology

authors： Collins CT,Gibson RA,McPhee AJ,Makrides M

更新日期：2019-11-01 00:00:00

abstract：:Abruptio placentae is an important cause of vaginal bleeding in the latter half of pregnancy. The key factor in the pathophysiology is hemorrhage at the decidual-placental interface. Small episodes may escape clinical detection, but severe grades impact significantly on fetal and maternal morbidity and mortality, with...

journal_title：Seminars in perinatology

authors： Hall DR

更新日期：2009-06-01 00:00:00

abstract：:Infant mortality, fetal mortality, and preterm birth all represent important health challenges that have shown little recent improvement. The rate of decrease in both fetal and infant mortality has slowed in recent years, with little decrease since 2000 for infant mortality, and no significant decrease from 2003 to 20...

journal_title：Seminars in perinatology

authors： MacDorman MF

更新日期：2011-08-01 00:00:00

abstract：:Inhaled nitric oxide (iNO), a selective pulmonary vasodilator, is available for treatment of persistent pulmonary hypertension of the newborn in term and near-term neonates. iNO decreases pulmonary vascular resistance leading to diminished extrapulmonary shunt and also has a microselective effect which improves ventil...

journal_title：Seminars in perinatology

authors： Kinsella JP,Abman SH

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:Cardiovascular disease is the major cause of pregnancy-related maternal mortality in the United States, and congenital heart disease (CHD) is the most common form of structural heart disease affecting women of childbearing age. Most females born with CHD will reach childbearing age and consider pregnancy. Adu...

journal_title：Seminars in perinatology

authors： Connolly HM

更新日期：2018-02-01 00:00:00

abstract：:Nitric oxide (NO) is intimately involved in vascular homeostasis through its antiplatelet, antiproliferative, and vasodilating actions. Because of these beneficial properties, methods of harnessing NO for the prevention of vascular injury responses, such as intimal hyperplasia, are being explored. One such method invo...

journal_title：Seminars in perinatology

authors： Kibbe MR,Tzeng E

更新日期：2000-02-01 00:00:00

abstract：:Hydrops fetalis, a condition characterized by abnormal accumulation of fluid and edema in the fetus, is the final common pathway in a number of pathological conditions. The diagnosis of hydrops is based on ultrasonographic findings of generalized edema along with a serous effusion (ascites, pleural effusion, or perica...

journal_title：Seminars in perinatology

authors： Bullard KM,Harrison MR

更新日期：1995-12-01 00:00:00

abstract：:Medium- and long-term outcomes have been collected and described among survivors of neonatal intensive care units for decades, for a number of purposes: (1) quality control within units, (2) comparisons of outcomes between NICUs, (3) clinical trials (whether an intervention improves outcomes), (4) end-of-life decision...

journal_title：Seminars in perinatology

authors： Janvier A,Farlow B,Baardsnes J,Pearce R,Barrington KJ

更新日期：2016-12-01 00:00:00

abstract：:The management of conjoined twins is complex and requires careful preparation. Pre-birth management includes prenatal counseling, which is important due to the overall poor prognosis. In instances of trial of life, the delivery must be tailored to address the anticipated anatomy based on prenatal imaging and anticipat...

journal_title：Seminars in perinatology

authors： C Sager E,Thomas A,C Sundgren N

更新日期：2018-10-01 00:00:00

abstract：:Here we provide a brief overview of the natural process of labor and its biochemical, hormonal, and mechanical characteristics that can be exploited in methods employed for induction of labor. ...

journal_title：Seminars in perinatology

authors： Irani RA,Foster S

更新日期：2015-10-01 00:00:00

abstract：:Prostaglandins are currently used to maintain patency of the ductus arteriosus and to elicit uterine contractions. Prostaglandin synthesis inhibitors are used to promote closure of the ductus and their administration in pregnant animals has produced fetal pulmonary hypertension. Exposure of the human fetus to inhibito...

journal_title：Seminars in perinatology

authors： Wendelberger KJ

更新日期：1987-01-01 00:00:00

abstract：:Increased hemolysis in the presence of severe neonatal hyperbilirubinemia appears to augment the risk of bilirubin neurotoxicity. The mechanism of this intensifying effect is uncertain. In direct antiglobulin titer (DAT) positive, isoimmune hemolytic disease, the bilirubin threshold at which neurotoxicity occurs appea...

journal_title：Seminars in perinatology

authors： Kaplan M,Bromiker R,Hammerman C

更新日期：2014-11-01 00:00:00

abstract：:Before sounds originating outside the abdomen of pregnant women can reach the inner ear of the fetus, they must first pass through the tissues and fluids surrounding the fetal head. Low-frequency sound energy easily penetrates to the fetal head, less than 5 dB attenuation for frequencies below 500 Hz, whereas higher f...

journal_title：Seminars in perinatology

authors： Gerhardt KJ,Abrams RM

更新日期：1996-02-01 00:00:00

abstract：:With 50-90% of pregnant women experiencing nausea and vomiting of pregnancy (NVP), the burden of illness can become quite significant if symptoms are under-treated and/or under-diagnosed, thus allowing for progression of the disease. The majority of these women will necessitate at least one visit with a provider to sp...

journal_title：Seminars in perinatology

authors： Clark SM,Dutta E,Hankins GD

更新日期：2014-12-01 00:00:00

abstract：:Obesity is a major risk factor for many obstetrical complications, including pre-eclampsia, gestational diabetes, indicated preterm birth, macrosomia, and stillbirth. Clinicians should be aware of the unique obstetrical management considerations related to obesity, including recommendations for alterations in prenatal...

journal_title：Seminars in perinatology

authors： Thornburg LL

更新日期：2011-12-01 00:00:00

abstract：:Maternal obesity, excessive gestational weight gain, and preexisting diabetes are known risk factors for increased maternal and neonatal morbidity. These conditions are more prevalent in certain racial and ethnic minorities. Identification and acknowledgement of racial and ethnic inequalities related to maternal metab...

journal_title：Seminars in perinatology

authors： Teefey CP,Durnwald CP

更新日期：2017-08-01 00:00:00

abstract：:Use of immunosuppressants during pregnancy is indicated for anti-rejection therapy in transplantation patients and treatment of autoimmune diseases. Maternal side effects include nephrotoxocity and hepatotoxicity. All immunosuppressant drugs cross the placenta. Immunosuppressant use during the first trimester is not s...

journal_title：Seminars in perinatology

authors： Little BB

更新日期：1997-04-01 00:00:00

abstract：:Poor access to contraception can lead to several undesired health outcomes, including high rates of unintended pregnancy, high rates of teen pregnancy, spontaneous preterm delivery, preeclampsia and maternal death. Properly addressing these public health issues often require a coordinated response at the state governm...

journal_title：Seminars in perinatology

authors： Jackson AD,Sherpa ML

更新日期：2020-08-01 00:00:00

abstract：:Traditional birth attendants (TBAs) provided delivery care throughout the world prior to the development of organized systems of medical care. In 2016, an estimated 22% of pregnant women delivered with a TBA, mostly in rural or remote areas that lacked formal health services. Still active in many regions of LMICs, the...

journal_title：Seminars in perinatology

authors： Garces A,McClure EM,Espinoza L,Saleem S,Figueroa L,Bucher S,Goldenberg RL

更新日期：2019-08-01 00:00:00

abstract：:The words research and experimentation continue to have the power to evoke fear in potential subjects. But much of standard practice, particularly in critical care settings, involves interventions of unknown efficacy and safety. Innovation also abounds in practice settings, typically unchecked by prospective or retros...

journal_title：Seminars in perinatology

authors： Fost N

更新日期：1998-06-01 00:00:00

abstract：:Ultrasound has permeated the practice of anesthesiology and is becoming an essential tool for the obstetric anesthesiologist in the labor and delivery suite. The most common applications include guidance for neuraxial (epidural and spinal) anesthesia and acute pain nerve blocks, as well as guidance for central and per...

journal_title：Seminars in perinatology

authors： Lee A

更新日期：2014-10-01 00:00:00

abstract：:The cause for most cases of cerebral palsy is unknown. There are however, risk factors that have been associated with this chronic neuromuscular disease. The objective of this article is to review the maternal and fetal conditions (other than asphyxia and infection) strongly associated with increased rate of cerebral ...

journal_title：Seminars in perinatology

authors： Ramin SM,Gilstrap LC 3rd

更新日期：2000-06-01 00:00:00

abstract：:Pulmonary aspiration of gastric contents is a leading cause of maternal morbidity and mortality for patients during labor. The risk is increased in those women who require obstetric surgery and general anesthesia. Furthermore, gastric aspiration is believed to be largely preventable. Care providers can reduce the risk...

journal_title：Seminars in perinatology

authors： Rowe TF

更新日期：1997-08-01 00:00:00

abstract：:Tumors are a rare but important cause of mortality and morbidity in the neonate. There is a wide spectrum of benign and malignant tumors that can occur, some of which have a unique presentation and behavior in this age group. It is important to recognize that tumors such as stage IVS neuroblastoma, which have a good p...

journal_title：Seminars in perinatology

authors： Weitzman S,Grant R

更新日期：1997-02-01 00:00:00

abstract：:This review documents and assesses recent trends in sudden infant death syndrome. We review medical literature, Internet resources, and national governmental data. A striking reduction in SIDS incidence of more than 50% has been observed in various countries after interventions, particularly during the early 1990s, to...

journal_title：Seminars in perinatology

authors： Ponsonby AL,Dwyer T,Cochrane J

更新日期：2002-08-01 00:00:00

abstract：:Newborn screening (NBS) reaches approximately all of the 4 million newborns in the United States each year and has been effective in significantly reducing the morbidity and mortality that results from certain congenital conditions. The comprehensive NBS system can be divided into preanalytic (education and screening)...

journal_title：Seminars in perinatology

authors： Therrell BL Jr,Schwartz M,Southard C,Williams D,Hannon WH,Mann MY,PEAS Organizing and Working Groups.

更新日期：2010-04-01 00:00:00

abstract：:A single course of antenatal corticosteroids is a rare example of a treatment that yields both a health benefit and a cost savings. This article reviews the history and background of antenatal corticosteroids, its use in clinical practice and the controversy today regarding the use of multiple courses of antenatal cor...

journal_title：Seminars in perinatology

authors： Murphy K,Aghajafari F,Hannah M

更新日期：2001-10-01 00:00:00

abstract：:The onset of preeclampsia at or near to term is associated with low maternal and neonatal morbidity and mortality. In contrast, those patients (1%) who suffer early onset preeclampsia engender significant maternal and perinatal morbidity and mortality. Therefore, because of the lack of proven prophylaxis for preeclamp...

journal_title：Seminars in perinatology

authors： Myatt L,Miodovnik M

更新日期：1999-02-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality among infants in the neonatal intensive care unit. Here we review the epidemiology and pathophysiology of NEC, with an emphasis on the latest research findings and potential areas for future research. NEC continues to be one of the most deva...

journal_title：Seminars in perinatology

authors： Lin PW,Nasr TR,Stoll BJ

更新日期：2008-04-01 00:00:00