Cellular antibiotic pharmacology.

abstract：:Venous thromboembolism (VTE) is a leading cause of severe maternal morbidity and mortality. While pregnancy alone is a risk factor for VTE, additional population-based risk factors such as obesity are becoming increasingly common, particularly in the developed world. Maternal death from VTE is amenable to prevention a...

journal_title：Seminars in perinatology

authors： Friedman AM,Ananth CV

更新日期：2016-03-01 00:00:00

abstract：:Poor access to contraception can lead to several undesired health outcomes, including high rates of unintended pregnancy, high rates of teen pregnancy, spontaneous preterm delivery, preeclampsia and maternal death. Properly addressing these public health issues often require a coordinated response at the state governm...

journal_title：Seminars in perinatology

authors： Jackson AD,Sherpa ML

更新日期：2020-08-01 00:00:00

abstract：:STDs can be one of the most common antepartum complications in high-risk gravidas. Screening for gonorrhea, syphilis, HPV, and possibly hepatitis B and chlamydial infection, should be considered in most, if not all, pregnant women. Familiarity with the common clinical presentations and treatment of bacterial STDs will...

journal_title：Seminars in perinatology

authors： Wendel GD Jr

更新日期：1990-04-01 00:00:00

abstract：:Mothers' genetics as well as their environment, behaviors, and social determinants of health are all important factors influencing short and long term childhood outcomes. There is an emerging body of literature investigating the extent to which fathers also contribute to their offspring's future health. We review fath...

journal_title：Seminars in perinatology

authors： Brumberg HL,Shah SI

更新日期：2020-06-01 00:00:00

abstract：:Understanding the role of ion channels in the generation of slow waves and action potentials in the myometrium is critical in designing strategies to regulate uterine contractile activity. The development of the patch clamp technique has allowed the identification of specific types of channels in the myometrium and pr...

journal_title：Seminars in perinatology

authors： Sanborn BM

更新日期：1995-02-01 00:00:00

abstract：:Infants meeting retinopathy of prematurity (ROP) screening guidelines based on birth weight and gestational age undergo serial examinations by ophthalmologists for detection and treatment. However, less than 10% require treatment, and less than half develop ROP. Slow postnatal weight gain is highly predictive of ROP, ...

journal_title：Seminars in perinatology

authors： Lin L,Binenbaum G

更新日期：2019-10-01 00:00:00

abstract：:The outcome literature on low birthweight (LBW) premature children indicates that they are at risk for a variety of neurodevelopmental impairments throughout childhood. To prevent such disabilities, numerous interventions have been initiated with LBW children. Nineteen intervention programs designed for LBW preterms t...

journal_title：Seminars in perinatology

authors： McCarton CM,Wallace IF,Bennett FC

更新日期：1995-08-01 00:00:00

abstract：:Sleep-disordered breathing occurs in 0.6-15% of reproductive age women. This condition is associated with an increased lifetime risk of cardiovascular disease, cardiovascular mortality, and all-cause mortality. A substantial body of evidence demonstrated increased perinatal morbidity among pregnancies affected by SDB ...

journal_title：Seminars in perinatology

authors： Cain MA,Ricciuti J,Louis JM

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Breastmilk is recommended as the exclusive source of nutrition for infants younger than 6 months due to the numerous health benefits for both infants and mothers. Although many women are prescribed medications during pregnancy and postpartum, limited data are available to assist women in weighing the benefits...

journal_title：Seminars in perinatology

authors： Sprague J,Wisner KL,Bogen DL

更新日期：2020-04-01 00:00:00

abstract：:The use of broad spectrum antimicrobials, the emergence of multiresistant organisms, and the hospital drug costs associated with antimicrobials have all driven the need for institutions to develop strategies to control the use of antimicrobials. Formulary restrictions, prior approval mechanisms, treatment guidelines, ...

journal_title：Seminars in perinatology

authors： Kubin CJ

更新日期：2002-10-01 00:00:00

abstract：:Determining approach to delivery after a previous cesarean is among the most contentious areas of obstetrics. We present a framework for ethically responsible guidelines and practice regarding vaginal birth after cesarean. We describe ethical complexities of 3 key issues that mark the debate: the cesarean delivery rat...

journal_title：Seminars in perinatology

authors： Lyerly AD,Little MO

更新日期：2010-10-01 00:00:00

abstract：:Hydrops fetalis, a condition characterized by abnormal accumulation of fluid and edema in the fetus, is the final common pathway in a number of pathological conditions. The diagnosis of hydrops is based on ultrasonographic findings of generalized edema along with a serous effusion (ascites, pleural effusion, or perica...

journal_title：Seminars in perinatology

authors： Bullard KM,Harrison MR

更新日期：1995-12-01 00:00:00

abstract：:This review evaluates and compares, by using the best available medical evidence, the risks and benefits of postnatal steroid use in very low birth weight infants. Systemic postnatal steroids are effective at reducing the risk of chronic lung disease in ventilated very low birth weight infants; they appear to be most ...

journal_title：Seminars in perinatology

authors： Kennedy KA

更新日期：2001-12-01 00:00:00

abstract：:Adverse pregnancy outcome from environmental factors may include congenital anomalies, increased risk for miscarriage, preterm delivery, intrauterine growth restriction, and still birth. Apart from adverse pregnancy outcome, there may be effects on the other reproductive functions, like menstrual disorders and inferti...

journal_title：Seminars in perinatology

authors： Triche EW,Hossain N

更新日期：2007-08-01 00:00:00

abstract：:Invasive candidiasis (IC) is a leading cause of morbidity and mortality in preterm infants. Even if successfully treated, IC can cause significant neurodevelopmental impairment. Preterm infants are at increased risk for hematogenous Candida meningoencephalitis owing to increased permeability of the blood-brain barrier...

journal_title：Seminars in perinatology

authors： Tripathi N,Watt K,Benjamin DK Jr

更新日期：2012-12-01 00:00:00

abstract：:Transplant recipients are becoming pregnant with increasing frequency, and successful pregnancy outcomes have now been reported for women with all types of solid organ transplants. To prevent rejection of the transplanted organ, these patients are maintained on a life-long immunosuppressive regimen that must also be c...

journal_title：Seminars in perinatology

authors： Fuchs KM,Coustan DR

更新日期：2007-12-01 00:00:00

abstract：:The management of conjoined twins is complex and requires careful preparation. Pre-birth management includes prenatal counseling, which is important due to the overall poor prognosis. In instances of trial of life, the delivery must be tailored to address the anticipated anatomy based on prenatal imaging and anticipat...

journal_title：Seminars in perinatology

authors： C Sager E,Thomas A,C Sundgren N

更新日期：2018-10-01 00:00:00

abstract：:The genetic sonogram is a composite algorithm combining multiple individual markers to increase Down syndrome risk prediction. Transformation of sonographic information into a standard mathematical format represented an early challenge that has now been surmounted. Using increasingly sophisticated mathematical techniq...

journal_title：Seminars in perinatology

authors： Bahado-Singh RO,Oz UA,Mendilcioglu I,Mahoney MJ

更新日期：2005-08-01 00:00:00

abstract：:The placenta was classically considered a barrier, but in 1957 this notion was shattered. This organ is only a selective filter and metabolic site. In this review, the placental transfer of the top 17 substances of abuse are analyzed. In the National Library of Medicine only 41 papers that documented placental transfe...

journal_title：Seminars in perinatology

authors： Little BB,VanBeveren TT

更新日期：1996-04-01 00:00:00

abstract：:The number of pregnant women who have type 2 diabetes and the number found to have gestational diabetes are progressively increasing. In the future, as many as 20% of pregnant women may be diagnosed with diabetes. Although there is consensus regarding many issues in the treatment of pregnant women with diabetes, there...

journal_title：Seminars in perinatology

authors： Catalano PM,Sacks DA

更新日期：2011-10-01 00:00:00

abstract：:The incidence of twins, triplets, and high-order multiples has increased dramatically in the last two decades secondary to greater reliance on fertility treatments and to delayed childbearing. Offspring of a multiple gestation are at increased risk for both chromosomal and structural abnormalities. Prenatal diagnosis ...

journal_title：Seminars in perinatology

authors： Cleary-Goldman J,D'Alton ME,Berkowitz RL

更新日期：2005-10-01 00:00:00

abstract：:Accurate assessment of fetal growth status requires the definition of an optimal standard, which represents the growth potential of the baby. Against this standard, individually 'customized' percentiles can be calculated. They improve the distinction between normal and abnormal, and help in our understanding and diagn...

journal_title：Seminars in perinatology

authors： Gardosi J

更新日期：2004-02-01 00:00:00

abstract：:Nutrition plays a critical role in the prevention and management of bronchopulmonary dysplasia (BPD). Growth failure in infants with BPD is predominantly due to malnutrition. Malnutrition can worsen BPD by compromising lung growth. Feeding difficulties in these infants can further affect nutrition. Dexamethasone, used...

journal_title：Seminars in perinatology

authors： Biniwale MA,Ehrenkranz RA

更新日期：2006-08-01 00:00:00

abstract：:Prostaglandins PGE2, PGD2, PGI2, and PGF2 alpha, as well as thromboxanes and leukotrienes, are synthesized by the fetal and neonatal kidney. The major prostaglandin, PGE2, PGD2, and PGI2, increase RBF, free water clearance, urine flow, and natriuresis. Alterations in the synthetic and catabolic activity of renal prost...

journal_title：Seminars in perinatology

authors： Gleason CA

更新日期：1987-01-01 00:00:00

abstract：:The cause for most cases of cerebral palsy is unknown. There are however, risk factors that have been associated with this chronic neuromuscular disease. The objective of this article is to review the maternal and fetal conditions (other than asphyxia and infection) strongly associated with increased rate of cerebral ...

journal_title：Seminars in perinatology

authors： Ramin SM,Gilstrap LC 3rd

更新日期：2000-06-01 00:00:00

abstract：:Inhaled nitric oxide (iNO), a selective pulmonary vasodilator, is available for treatment of persistent pulmonary hypertension of the newborn in term and near-term neonates. iNO decreases pulmonary vascular resistance leading to diminished extrapulmonary shunt and also has a microselective effect which improves ventil...

journal_title：Seminars in perinatology

authors： Kinsella JP,Abman SH

更新日期：2000-12-01 00:00:00

abstract：:Ethics is an essential dimension of the management of periviable birth in both clinical practice and research. The goal of clinical care in periviable birth is to improve outcomes for current pregnant and fetal patients. The goal of research in periviable birth is to improve outcomes for future pregnant patients and f...

journal_title：Seminars in perinatology

authors： Chervenak FA,McCullough LB

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:Cardiovascular disease is the major cause of pregnancy-related maternal mortality in the United States, and congenital heart disease (CHD) is the most common form of structural heart disease affecting women of childbearing age. Most females born with CHD will reach childbearing age and consider pregnancy. Adu...

journal_title：Seminars in perinatology

authors： Connolly HM

更新日期：2018-02-01 00:00:00

abstract：:The studies described above collectively suggest that, whenever there is a decrease in fluid balance in the fetus, both fetal urine flow and tracheal secretion into the amniotic space are decreased. Conversely, when fetal hydration is increased, both urine and tracheal flows into the amniotic fluid may be increased. T...

journal_title：Seminars in perinatology

authors： Brace RA

更新日期：1986-04-01 00:00:00

abstract：:We have hypothesized that an alteration in the production of endothelium-dependent factors by sex hormones is a potential unifying mechanism for both the decreased arterial contractility and the redistribution of cardiac output characteristic of normal pregnancy. Thus, the effect of pregnancy/ estradiol on any one vas...

journal_title：Seminars in perinatology

authors： Weiner CP,Thompson LP

更新日期：1997-10-01 00:00:00