Obstetrical venous thromboembolism: Epidemiology and strategies for prophylaxis.

Abstract:

:Venous thromboembolism (VTE) is a leading cause of severe maternal morbidity and mortality. While pregnancy alone is a risk factor for VTE, additional population-based risk factors such as obesity are becoming increasingly common, particularly in the developed world. Maternal death from VTE is amenable to prevention and VTE thromboprophylaxis is the most readily implementable means of systematically reducing the maternal death rate. In the United States, prophylaxis is recommended primarily for patients at extremely high risk for thromboembolism and women undergoing cesarean delivery, whereas in the United Kingdom a larger proportion of the population is targeted. Given the maternal burden of obstetric VTE and varying strategies for prevention, this article will provide a review of the following topics: (1) global epidemiology of obstetric VTE, (2) prophylaxis guidelines in the United States and the United Kingdom, and (3) maternal mortality from VTE in the United States and the United Kingdom in the setting of differing prophylaxis strategies.

journal_name

Semin Perinatol

journal_title

Seminars in perinatology

authors

Friedman AM,Ananth CV

doi

10.1053/j.semperi.2015.11.011

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

81-6

issue

2

eissn

0146-0005

issn

1558-075X

pii

S0146-0005(15)00171-8

journal_volume

40

pub_type

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