Aortopathy in pregnancy.

abstract：:Gene therapy carries the potential to treat more than 10,000 human monogenic diseases and benefit an even greater number of complex polygenic conditions. The repurposing of CRISPR/Cas9, an ancient bacterial immune defense system, into a gene-editing technology has armed researchers with a revolutionary tool for gene t...

journal_title：Seminars in perinatology

authors： Memi F,Ntokou A,Papangeli I

更新日期：2018-12-01 00:00:00

abstract：:The outcome literature on low birthweight (LBW) premature children indicates that they are at risk for a variety of neurodevelopmental impairments throughout childhood. To prevent such disabilities, numerous interventions have been initiated with LBW children. Nineteen intervention programs designed for LBW preterms t...

journal_title：Seminars in perinatology

authors： McCarton CM,Wallace IF,Bennett FC

更新日期：1995-08-01 00:00:00

abstract：:Late preterm infants (34-37 weeks gestation) pose unique challenges to physicians and nurses involved in their care after birth. They may be cared for in different units within hospitals after birth, including Neonatal Intensive Care Units, Newborn Nurseries, or rooming in with the mother. As a result of their gestati...

journal_title：Seminars in perinatology

authors： Laptook A,Jackson GL

更新日期：2006-02-01 00:00:00

abstract：:Candida is a leading cause of late onset infection (> 3 days of age) in the premature infant. Therefore, decisions about the diagnosis and management of infections caused by Candida are commonplace in the neonatal intensive care unit. Despite this fact, there are few comparative trials about treatment of neonatal Cand...

journal_title：Seminars in perinatology

authors： Bliss JM,Wellington M,Gigliotti F

更新日期：2003-10-01 00:00:00

abstract：:Seizures during pregnancy complicate <1% of all gestations; however, they are associated with increased adverse maternal and perinatal outcomes (acute and long term). The differential diagnosis of seizures in pregnancy is extensive. Determining the underlying etiology is crucial in the management of these patients. Me...

journal_title：Seminars in perinatology

authors： Hart LA,Sibai BM

更新日期：2013-08-01 00:00:00

abstract：:The process of parturition is poorly understood, but the cervix clearly plays a key role. Because of this, recent research efforts have been directed at objective quantification of cervical remodeling. Investigation has focused on two basic areas: (1) quantification of tissue deformability and (2) presence, orientatio...

journal_title：Seminars in perinatology

authors： Feltovich H,Carlson L

更新日期：2017-12-01 00:00:00

abstract：:The primary methods currently in use for imaging the infant brain are cranial ultrasound (CUS), computed tomography (CT) and magnetic resonance imaging (MRI). This review outlines the relative strengths and weaknesses of these modalities in relation to the premature infant, with specific focus on the correlations betw...

journal_title：Seminars in perinatology

authors： Neil JJ,Inder TE

更新日期：2004-12-01 00:00:00

abstract：:The safety of cesarean section has improved dramatically over the past 50 years. During the past 20 years a greater awareness of and discussion about the symptomatic morbidity that can result for women following vaginal delivery has occurred and women's expectations for the outcome of pregnancy for them and their babi...

journal_title：Seminars in perinatology

authors： Morrison J,MacKenzie IZ

更新日期：2003-02-01 00:00:00

abstract：:Neonatal herpes simplex virus (HSV) infection is one of the life-threatening infections of newborns. It affects approximately 1,500 to 2,200 infants per year in the United States. Changes in the presentation of neonatal HSV infection over the past two decades include an increase in the frequency of skin, eye, and mout...

journal_title：Seminars in perinatology

authors： Jacobs RF

更新日期：1998-02-01 00:00:00

abstract：:Medium- and long-term outcomes have been collected and described among survivors of neonatal intensive care units for decades, for a number of purposes: (1) quality control within units, (2) comparisons of outcomes between NICUs, (3) clinical trials (whether an intervention improves outcomes), (4) end-of-life decision...

journal_title：Seminars in perinatology

authors： Janvier A,Farlow B,Baardsnes J,Pearce R,Barrington KJ

更新日期：2016-12-01 00:00:00

abstract：:Inhaled nitric oxide (iNO), a selective pulmonary vasodilator, is available for treatment of persistent pulmonary hypertension of the newborn in term and near-term neonates. iNO decreases pulmonary vascular resistance leading to diminished extrapulmonary shunt and also has a microselective effect which improves ventil...

journal_title：Seminars in perinatology

authors： Kinsella JP,Abman SH

更新日期：2000-12-01 00:00:00

abstract：:Late preterm infants (34-37 weeks postmenstrual age at birth) are intermediate between less mature preterm infants and infants born at 38 weeks or more in regard to autonomic brain stem maturation. Ventilatory responses to CO(2) in preterm infants born at 33 to 36 week are significantly higher than in infants born at ...

journal_title：Seminars in perinatology

authors： Hunt CE

更新日期：2006-04-01 00:00:00

abstract：:Long-term sequelae of preterm birth have been studied extensively up until the age of 5 to 8 years. However, the cognitive development of adolescents born preterm has received limited attention. The objective of this study is to determine school performance in adolescents born very preterm. We have followed up a cohor...

journal_title：Seminars in perinatology

authors： van de Bor M,den Ouden L

更新日期：2004-08-01 00:00:00

abstract：:Clinically silent upper genital tract microbial infections have been strongly associated with spontaneous preterm delivery, especially prior to 32 weeks gestational age. This condition represents a potentially preventable or reversible cause of preterm birth using safe, readily available, and inexpensive antibiotics. ...

journal_title：Seminars in perinatology

authors： Andrews WW,Goldenberg RL,National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

更新日期：2003-06-01 00:00:00

abstract：:Classical and subtypes of kernicterus associated with bilirubin toxicity can be differentiated in part with physiological auditory measures that include auditory-evoked potentials and measures of cochlear integrity. The combination of these auditory measures suggests that bilirubin exposure results in auditory system ...

journal_title：Seminars in perinatology

authors： Shapiro SM,Popelka GR

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:The purpose of this analysis was to determine the impact on specific forms of neonatal morbidity and mortality by allowing women to opt for delivery by elective cesarean section at 39 weeks of gestation (EGA). According to the National Vital Statistics Reports, over 70% of deliveries in the U.S. annually are at...

journal_title：Seminars in perinatology

authors： Hankins GD,Clark SM,Munn MB

更新日期：2006-10-01 00:00:00

abstract：:Use of immunosuppressants during pregnancy is indicated for anti-rejection therapy in transplantation patients and treatment of autoimmune diseases. Maternal side effects include nephrotoxocity and hepatotoxicity. All immunosuppressant drugs cross the placenta. Immunosuppressant use during the first trimester is not s...

journal_title：Seminars in perinatology

authors： Little BB

更新日期：1997-04-01 00:00:00

abstract：:The medical literature demonstrates that inadequate hospital protocols or the lack of consistent protocols for diagnosis, management, consultation, and/or referral can lead to confusion and unnecessary variation in patient care. Incongruities in clinical settings have been repeatedly shown to compromise quality of pat...

journal_title：Seminars in perinatology

authors： Burgansky A,Montalto D,Siddiqui NA

更新日期：2016-03-01 00:00:00

abstract：:The complex nature of amniotic fluid reflects contributions from many fetal systems, many functional roles, and multiple interactions with fetal maturation, obstetric, and maternal factors. Simple ultrasound measurement, probably done best with the maximum vertical pocket method, has a clinical role in fetal surveilla...

journal_title：Seminars in perinatology

authors： Harman CR

更新日期：2008-08-01 00:00:00

abstract：:Hormones are necessary for the growth of mammary glands, for initiation of the secretory process, and for the maintenance of an established lactation in all mammals. Hormonal changes which occur in late pregnancy and the early postpartum period are described and graphed. This data was derived from research with anim...

journal_title：Seminars in perinatology

authors： Tucker HA

更新日期：1979-07-01 00:00:00

abstract：:Accurate assessment of fetal growth status requires the definition of an optimal standard, which represents the growth potential of the baby. Against this standard, individually 'customized' percentiles can be calculated. They improve the distinction between normal and abnormal, and help in our understanding and diagn...

journal_title：Seminars in perinatology

authors： Gardosi J

更新日期：2004-02-01 00:00:00

abstract：:The importance of omega-3 long chain polyunsaturated fatty acids in the perinatal period has been the focus of research for several decades. Infants born preterm miss out on the last trimester in utero transfer of omega-3 fatty acids and consequently have lower blood levels than infants born at term. Preterm infant fo...

journal_title：Seminars in perinatology

authors： Collins CT,Gibson RA,McPhee AJ,Makrides M

更新日期：2019-11-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection is the most common perinatal infection and may result in severe injury to the fetus. Forty percent to 50% of infants delivered to mothers with primary CMV will have congenital infections. Of these, 5% to 18% will be overtly symptomatic at birth. The mortality rate in these children is a...

journal_title：Seminars in perinatology

authors： Brown HL,Abernathy MP

更新日期：1998-08-01 00:00:00

abstract：:In initiating enteral feedings for high-risk infants, clinicians struggle with three fundamental questions: When should enteral feedings be initiated? Should a period of trophic (minimal) feeding be provided? When feedings are advanced, how rapidly should the volume be increased? We present the findings of our systema...

journal_title：Seminars in perinatology

authors： Tyson JE,Kennedy KA,Lucke JF,Pedroza C

更新日期：2007-04-01 00:00:00

abstract：:Unpublished results can bias biomedical literature, favoring positive over negative findings, primary over secondary analyses, and can lead to duplicate studies that unnecessarily endanger subjects and waste resources. The Neonatal Research Network's (NRN) publication policies for approving, reviewing, and tracking ab...

journal_title：Seminars in perinatology

authors： Archer SW,Carlo WA,Truog WE,Stevenson DK,Van Meurs KP,Sánchez PJ,Das A,Devaskar U,Nelin LD,Petrie Huitema CM,Crawford MM,Higgins RD,Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research

更新日期：2016-10-01 00:00:00

abstract：:The incidence of twin gestation has increased significantly over the past 30 years. One of the most significant public health implications of this trend is the increased incidence of preterm birth (PTB). Efforts to improve neonatal outcomes must address the rate of PTB, particularly among multiple gestations, which co...

journal_title：Seminars in perinatology

authors： Brubaker SG,Gyamfi C

更新日期：2012-06-01 00:00:00

abstract：:Multiple gestation carries a significant risk of perinatal complications and mortality. Often twin neonates are delivered small and early with a perinatal mortality rate five to seven times that of singleton neonates. Increased morbidity and mortality is due to an increased incidence of antepartum complications, monoz...

journal_title：Seminars in perinatology

authors： Newton ER

更新日期：1986-01-01 00:00:00

abstract：:The intended and unintended effects of epidural labor analgesia are reviewed. Mothers randomized to epidural rather than parenteral opioid analgesia have better pain relief. Fetal oxygenation is not affected by analgesic method; however, neonates whose mothers received intravenous or intramuscular opioids rather than ...

journal_title：Seminars in perinatology

authors： Leighton BL,Halpern SH

更新日期：2002-04-01 00:00:00

abstract：:Pulmonary aspiration of gastric contents is a leading cause of maternal morbidity and mortality for patients during labor. The risk is increased in those women who require obstetric surgery and general anesthesia. Furthermore, gastric aspiration is believed to be largely preventable. Care providers can reduce the risk...

journal_title：Seminars in perinatology

authors： Rowe TF

更新日期：1997-08-01 00:00:00

abstract：:In mammals, a master circadian clock resides in the suprachiasmatic nuclei of the anterior hypothalamus. The suprachiasmatic nuclei is composed of multiple, single-cell circadian oscillators, which, when synchronized, lead to coordinated circadian outputs that ultimately regulate overt rhythms. Several "clock genes" h...

journal_title：Seminars in perinatology

authors： Reppert SM

更新日期：2000-08-01 00:00:00