Immunosuppressant therapy during gestation.

abstract：:Hormones are necessary for the growth of mammary glands, for initiation of the secretory process, and for the maintenance of an established lactation in all mammals. Hormonal changes which occur in late pregnancy and the early postpartum period are described and graphed. This data was derived from research with anim...

journal_title：Seminars in perinatology

authors： Tucker HA

更新日期：1979-07-01 00:00:00

abstract：:Newborn screening (NBS) reaches approximately all of the 4 million newborns in the United States each year and has been effective in significantly reducing the morbidity and mortality that results from certain congenital conditions. The comprehensive NBS system can be divided into preanalytic (education and screening)...

journal_title：Seminars in perinatology

authors： Therrell BL Jr,Schwartz M,Southard C,Williams D,Hannon WH,Mann MY,PEAS Organizing and Working Groups.

更新日期：2010-04-01 00:00:00

abstract：:Seizures during pregnancy complicate <1% of all gestations; however, they are associated with increased adverse maternal and perinatal outcomes (acute and long term). The differential diagnosis of seizures in pregnancy is extensive. Determining the underlying etiology is crucial in the management of these patients. Me...

journal_title：Seminars in perinatology

authors： Hart LA,Sibai BM

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:The purpose of this analysis was to determine the impact on specific forms of neonatal morbidity and mortality by allowing women to opt for delivery by elective cesarean section at 39 weeks of gestation (EGA). According to the National Vital Statistics Reports, over 70% of deliveries in the U.S. annually are at...

journal_title：Seminars in perinatology

authors： Hankins GD,Clark SM,Munn MB

更新日期：2006-10-01 00:00:00

abstract：:Up to half of all aortic dissections and ruptures in women younger than 40 years are associated with pregnancy. In pregnancy, women with aortic disease such as arteritis and aortitis are at significant risk of aneurysmal formation and dissection with potential for catastrophic outcomes. Pregnancy places predisposed wo...

journal_title：Seminars in perinatology

authors： Smok DA

更新日期：2014-08-01 00:00:00

abstract：:Medical and psychological indications for lactation suppression are discussed, and methods for lactation suppression are evaluated. Medical indications for lactation suppression include 1) maternal anatomical abnormalities, such as inadequate secretory tissue and inverted nipples; 2) maternal breast infections and tu...

journal_title：Seminars in perinatology

authors： Harrison RG

更新日期：1979-07-01 00:00:00

abstract：:The product label required by the FDA for every drug approved for marketing in the US is a legal document that originates with the company that wants to market the drug, but it must be approved by the FDA. Despite the recognized limitations of registries, the FDA's new labeling rule, effective from July 1, 2015, has g...

journal_title：Seminars in perinatology

authors： Greene MF

更新日期：2015-11-01 00:00:00

abstract：:Gene therapy carries the potential to treat more than 10,000 human monogenic diseases and benefit an even greater number of complex polygenic conditions. The repurposing of CRISPR/Cas9, an ancient bacterial immune defense system, into a gene-editing technology has armed researchers with a revolutionary tool for gene t...

journal_title：Seminars in perinatology

authors： Memi F,Ntokou A,Papangeli I

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Cardiovascular disease is the major cause of pregnancy-related maternal mortality in the United States, and congenital heart disease (CHD) is the most common form of structural heart disease affecting women of childbearing age. Most females born with CHD will reach childbearing age and consider pregnancy. Adu...

journal_title：Seminars in perinatology

authors： Connolly HM

更新日期：2018-02-01 00:00:00

abstract：:Neonatal erythropoiesis is limited by a relatively inadequate production of erythropoietin. This is likely the result of dependence on the hepatic production of erythropoietin and an incomplete switchover to renal production. The present model of neonatal erythropoiesis suggests that the use of exogenous erythropoieti...

journal_title：Seminars in perinatology

authors： Doyle JJ

更新日期：1997-02-01 00:00:00

abstract：:The future health of infants and children is dependent on the performance of clinical research in which infants participate. Achieving a proper balance between this social good and the obligation to protect infants who participate in research is a significant challenge. As investigators design and implement research p...

journal_title：Seminars in perinatology

authors： Diekema DS

更新日期：2009-12-01 00:00:00

abstract：:Phototherapy for jaundice is a common treatment in neonatal medicine and is used to prevent the neurotoxic effects of bilirubin. Studies have assessed the optimal wavelength of phototherapy light, the importance of irradiance and spectral power, and the types of light source, including the use of single versus multipl...

journal_title：Seminars in perinatology

authors： Ruud Hansen TW

更新日期：2010-06-01 00:00:00

abstract：:Mothers' genetics as well as their environment, behaviors, and social determinants of health are all important factors influencing short and long term childhood outcomes. There is an emerging body of literature investigating the extent to which fathers also contribute to their offspring's future health. We review fath...

journal_title：Seminars in perinatology

authors： Brumberg HL,Shah SI

更新日期：2020-06-01 00:00:00

abstract：:The neurodevelopmental outcome of very low birth weight infants experiencing early-onset intraventricular hemorrhage (IVH) occurring within the first 6 postnatal hours was compared with that of their peers without early-onset IVH at 3 years corrected age. The 440 surviving preterm infants (birth weight 600 to 1,250 g)...

journal_title：Seminars in perinatology

authors： Vohr B,Allan WC,Scott DT,Katz KH,Schneider KC,Makuch RW,Ment LR

更新日期：1999-06-01 00:00:00

abstract：:Diagnostic errors remain understudied in neonatology. The limited available evidence, however, suggests that diagnostic errors in the neonatal intensive care unit (NICU) result in significant and long-term consequences. In this narrative review, we discuss how the concept of diagnostic errors framed as missed opportun...

journal_title：Seminars in perinatology

authors： Shafer G,Singh H,Suresh G

更新日期：2019-12-01 00:00:00

abstract：:Extreme hyperbilirubinemia can cause bilirubin neurotoxicity. Infants with glucose-6-phosphate dehydrogenase (G6PD) deficiency can develop hemolysis and thus are at high risk. We evaluated a device that quantitatively measures G6PD activity kinetically using digital microfluidics (DMF). Intra- and inter-instrument and...

journal_title：Seminars in perinatology

authors： Wong RJ,Montiel C,Kunda M,Stevenson DK,Bhutani VK

更新日期：2021-02-01 00:00:00

abstract：:Acute renal failure in the newborn is a common problem and is typically classified as prerenal, intrinsic renal disease including vascular insults, and obstructive uropathy. In the newborn, renal failure may have a prenatal onset in congenital diseases such as renal dysplasia with or without obstructive uropathy and i...

journal_title：Seminars in perinatology

authors： Andreoli SP

更新日期：2004-04-01 00:00:00

abstract：:Neonatal herpes simplex virus (HSV) infection is one of the life-threatening infections of newborns. It affects approximately 1,500 to 2,200 infants per year in the United States. Changes in the presentation of neonatal HSV infection over the past two decades include an increase in the frequency of skin, eye, and mout...

journal_title：Seminars in perinatology

authors： Jacobs RF

更新日期：1998-02-01 00:00:00

abstract：:Late preterm infants (34-37 weeks gestation) pose unique challenges to physicians and nurses involved in their care after birth. They may be cared for in different units within hospitals after birth, including Neonatal Intensive Care Units, Newborn Nurseries, or rooming in with the mother. As a result of their gestati...

journal_title：Seminars in perinatology

authors： Laptook A,Jackson GL

更新日期：2006-02-01 00:00:00

abstract：:Universal prenatal Rhesus (Rh) screening and prophylaxis with Rh immunoglobulin have been highly effective practices for preventing neonatal morbidities and mortality. However, there has been an enormous failure to prevent Rh sensitization and its adverse consequences worldwide, especially in low- and middle-income co...

journal_title：Seminars in perinatology

authors： Variane GF,Sant'Anna GM

更新日期：2021-02-01 00:00:00

abstract：:Neonatal hyperinsulinism (HI) is a clinical syndrome of pancreatic beta-cell dysfunction characterized by failure to suppress insulin secretion in the presence of hypoglycemia. Although rare, it is the most common cause for persistent hypoglycemia in the newborn period. Treatment can be extremely difficult, and partia...

journal_title：Seminars in perinatology

authors： Glaser B

更新日期：2000-04-01 00:00:00

abstract：:Inhalation of nitric oxide (NO) is an experimental treatment for severe pulmonary hypertension. Being rapidly metabolized by hemoglobin, inhaled NO causes selective vasodilation in the pulmonary vascular bed. In addition to the vascular smooth muscle, other pulmonary structures are exposed to inhaled NO, resulting in ...

journal_title：Seminars in perinatology

authors： Hallman M,Bry K

更新日期：1996-06-01 00:00:00

abstract：:The medical literature demonstrates that inadequate hospital protocols or the lack of consistent protocols for diagnosis, management, consultation, and/or referral can lead to confusion and unnecessary variation in patient care. Incongruities in clinical settings have been repeatedly shown to compromise quality of pat...

journal_title：Seminars in perinatology

authors： Burgansky A,Montalto D,Siddiqui NA

更新日期：2016-03-01 00:00:00

abstract：:Prostaglandins PGE2, PGD2, PGI2, and PGF2 alpha, as well as thromboxanes and leukotrienes, are synthesized by the fetal and neonatal kidney. The major prostaglandin, PGE2, PGD2, and PGI2, increase RBF, free water clearance, urine flow, and natriuresis. Alterations in the synthetic and catabolic activity of renal prost...

journal_title：Seminars in perinatology

authors： Gleason CA

更新日期：1987-01-01 00:00:00

abstract：:Twin birth rates have increased dramatically over the past three decades, and twins currently account for 3% of all pregnancies. Twin pregnancies of any type are at risk for prematurity. In addition, monochorionic twin pregnancies (25-30% of all twin pregnancies) are predisposed to a specific set of complications, inc...

journal_title：Seminars in perinatology

authors： Paepe ME

更新日期：2015-02-01 00:00:00

abstract：:The onset of preeclampsia at or near to term is associated with low maternal and neonatal morbidity and mortality. In contrast, those patients (1%) who suffer early onset preeclampsia engender significant maternal and perinatal morbidity and mortality. Therefore, because of the lack of proven prophylaxis for preeclamp...

journal_title：Seminars in perinatology

authors： Myatt L,Miodovnik M

更新日期：1999-02-01 00:00:00

abstract：:Fetal and neonatal alloimmune thrombocytopenia is not a well-known disease, except among specialists in maternal-fetal medicine, neonatologists, and certain pediatricians (ie, hematologists). However, this is by far the most common cause of early severe thrombocytopenia in neonates and of intracranial hemorrhage in te...

journal_title：Seminars in perinatology

authors： Bussel JB,Sola-Visner M

更新日期：2009-02-01 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is a chronic lung disease which develops as a result of neonatal/perinatal lung injury. It is the commonest cause of chronic lung disease in infancy and the most frequent morbidity associated with prematurity. The incidence of BPD has continued to rise despite many advances in neonatal...

journal_title：Seminars in perinatology

authors： Bhandari A,Panitch H

更新日期：2018-11-01 00:00:00

abstract：:While the cesarean delivery (CD) rates have increased worldwide, operative vaginal delivery (OVD) rates continue to decline, with the United States having some of the lower rates amongst developed countries. It is clear that the use of forceps or vacuum can safely assist in accomplishing a vaginal delivery and prevent...

journal_title：Seminars in perinatology

authors： Gei AF

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Pulmonary inflammation, increased production of the inflammatory cytokine interleukin-1beta (IL-1beta), and vitamin A deficiency are risk factors for the development of bronchopulmonary dysplasia (BPD) in premature infants. To determine the mechanisms by which IL-1beta influences lung development, we have ge...

journal_title：Seminars in perinatology

authors： Bry K,Lappalainen U

更新日期：2006-06-01 00:00:00