Examination of the twin placenta.

Abstract:

:Twin birth rates have increased dramatically over the past three decades, and twins currently account for 3% of all pregnancies. Twin pregnancies of any type are at risk for prematurity. In addition, monochorionic twin pregnancies (25-30% of all twin pregnancies) are predisposed to a specific set of complications, including twin-to-twin transfusion syndrome (TTTS), twin reversed arterial perfusion syndrome (TRAP), malformations, and intertwin growth discordance. This article reviews the basic mechanisms underlying the twinning process, the relationship between zygosity and chorionicity, and the various types of twinning. We describe the major complications of monochorionic twinning in association with their reported placental characteristics (or lack thereof). Finally, a rational, evidence-based approach to examination of the twin placenta is presented. It is essential for the pathologist to understand the value, strengths, and limitations of examination of the twin placenta in order to provide a meaningful clinicopathological correlation in complicated (monochorionic) twin pregnancies.

journal_name

Semin Perinatol

journal_title

Seminars in perinatology

authors

Paepe ME

doi

10.1053/j.semperi.2014.10.005

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

27-35

issue

1

eissn

0146-0005

issn

1558-075X

pii

S0146-0005(14)00120-7

journal_volume

39

pub_type

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