Oligohydramnios: problems and treatment.

abstract：:Use of immunosuppressants during pregnancy is indicated for anti-rejection therapy in transplantation patients and treatment of autoimmune diseases. Maternal side effects include nephrotoxocity and hepatotoxicity. All immunosuppressant drugs cross the placenta. Immunosuppressant use during the first trimester is not s...

journal_title：Seminars in perinatology

authors： Little BB

更新日期：1997-04-01 00:00:00

abstract：:Inhaled nitric oxide (iNO), a selective pulmonary vasodilator, is available for treatment of persistent pulmonary hypertension of the newborn in term and near-term neonates. iNO decreases pulmonary vascular resistance leading to diminished extrapulmonary shunt and also has a microselective effect which improves ventil...

journal_title：Seminars in perinatology

authors： Kinsella JP,Abman SH

更新日期：2000-12-01 00:00:00

abstract：:Asthma may be the most common potentialy serious medical problem to complicate pregnancy. Because severe uncontrolled asthma may cause both maternal and fetal morbidity and mortality, pharmacological asthma therapy is often necessary during pregnancy. Only 1 published randomized controlled clinical trial has evaluated...

journal_title：Seminars in perinatology

authors： Schatz M

更新日期：2001-06-01 00:00:00

abstract：:This article reviews the literature on infectious diseases as a cause of stillbirth. Identifying a specific infection as a cause of stillbirth is limited by many obstacles. Nevertheless, "good faith" efforts estimate that approximately 9% to 15% of stillbirths are caused by infections. Infection may be especially impo...

journal_title：Seminars in perinatology

authors： Gibbs RS

更新日期：2002-02-01 00:00:00

abstract：:Pulmonary aspiration of gastric contents is a leading cause of maternal morbidity and mortality for patients during labor. The risk is increased in those women who require obstetric surgery and general anesthesia. Furthermore, gastric aspiration is believed to be largely preventable. Care providers can reduce the risk...

journal_title：Seminars in perinatology

authors： Rowe TF

更新日期：1997-08-01 00:00:00

abstract：:Accurate assessment of fetal growth status requires the definition of an optimal standard, which represents the growth potential of the baby. Against this standard, individually 'customized' percentiles can be calculated. They improve the distinction between normal and abnormal, and help in our understanding and diagn...

journal_title：Seminars in perinatology

authors： Gardosi J

更新日期：2004-02-01 00:00:00

abstract：:Nuchal translucency (NT) describes an echo-free area, below the skin, in the posterior nuchal and back region of the fetus and is typically observed in the first and early second trimester of pregnancy. A wide NT has been correlated with chromosomal and congenital abnormalities in the fetus. An accurate NT measurement...

journal_title：Seminars in perinatology

authors： Abuhamad A

更新日期：2005-12-01 00:00:00

abstract：:Invasive candidiasis (IC) is a leading cause of morbidity and mortality in preterm infants. Even if successfully treated, IC can cause significant neurodevelopmental impairment. Preterm infants are at increased risk for hematogenous Candida meningoencephalitis owing to increased permeability of the blood-brain barrier...

journal_title：Seminars in perinatology

authors： Tripathi N,Watt K,Benjamin DK Jr

更新日期：2012-12-01 00:00:00

abstract：:Preeclampsia, intrauterine growth restriction (IUGR), and placental abruption are obstetrical conditions that constitute the syndrome of ischemic placental disease or IPD, the leading cause of indicated preterm birth and an important cause of neonatal morbidity and mortality. While the phenotypic manifestations vary s...

journal_title：Seminars in perinatology

authors： Friedman AM,Cleary KL

更新日期：2014-04-01 00:00:00

abstract：:The future health of infants and children is dependent on the performance of clinical research in which infants participate. Achieving a proper balance between this social good and the obligation to protect infants who participate in research is a significant challenge. As investigators design and implement research p...

journal_title：Seminars in perinatology

authors： Diekema DS

更新日期：2009-12-01 00:00:00

abstract：:The renin angiotensin system (RAS) is now recognized as the body's most powerful hormone system for controlling renal hemodynamics and sodium excretion and, therefore, body fluid volumes and arterial pressure. The discovery of angiotensin converting enzyme inhibitors (ACEi) was a keystone for the understanding of the ...

journal_title：Seminars in perinatology

authors： Ferreira SH

更新日期：2000-02-01 00:00:00

abstract：:The principal objective of antenatal testing is to detect fetal hypoxia before the fetus has suffered lasting harm. This article summarizes some of the mechanisms by which fetal oxygen consumption is maintained under normal conditions, and adaptations that occur in response to hypoxemia. Alterations in the fetal heart...

journal_title：Seminars in perinatology

authors： Martin CB Jr

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To describe inpatient management strategies and considerations for pregnant patients with severe acute respiratory syndrome coronavirus 2 infection. FINDINGS:The novel coronavirus has posed challenges to both obstetric patients and the staff caring for them, due to its variable presentation and current limit...

journal_title：Seminars in perinatology

authors： Aubey J,Zork N,Sheen JJ

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Pulmonary inflammation, increased production of the inflammatory cytokine interleukin-1beta (IL-1beta), and vitamin A deficiency are risk factors for the development of bronchopulmonary dysplasia (BPD) in premature infants. To determine the mechanisms by which IL-1beta influences lung development, we have ge...

journal_title：Seminars in perinatology

authors： Bry K,Lappalainen U

更新日期：2006-06-01 00:00:00

abstract：:Mothers' genetics as well as their environment, behaviors, and social determinants of health are all important factors influencing short and long term childhood outcomes. There is an emerging body of literature investigating the extent to which fathers also contribute to their offspring's future health. We review fath...

journal_title：Seminars in perinatology

authors： Brumberg HL,Shah SI

更新日期：2020-06-01 00:00:00

abstract：:Extreme hyperbilirubinemia can cause bilirubin neurotoxicity. Infants with glucose-6-phosphate dehydrogenase (G6PD) deficiency can develop hemolysis and thus are at high risk. We evaluated a device that quantitatively measures G6PD activity kinetically using digital microfluidics (DMF). Intra- and inter-instrument and...

journal_title：Seminars in perinatology

authors： Wong RJ,Montiel C,Kunda M,Stevenson DK,Bhutani VK

更新日期：2021-02-01 00:00:00

abstract：:In mammals, a master circadian clock resides in the suprachiasmatic nuclei of the anterior hypothalamus. The suprachiasmatic nuclei is composed of multiple, single-cell circadian oscillators, which, when synchronized, lead to coordinated circadian outputs that ultimately regulate overt rhythms. Several "clock genes" h...

journal_title：Seminars in perinatology

authors： Reppert SM

更新日期：2000-08-01 00:00:00

abstract：:Seizures during pregnancy complicate <1% of all gestations; however, they are associated with increased adverse maternal and perinatal outcomes (acute and long term). The differential diagnosis of seizures in pregnancy is extensive. Determining the underlying etiology is crucial in the management of these patients. Me...

journal_title：Seminars in perinatology

authors： Hart LA,Sibai BM

更新日期：2013-08-01 00:00:00

abstract：:We have hypothesized that an alteration in the production of endothelium-dependent factors by sex hormones is a potential unifying mechanism for both the decreased arterial contractility and the redistribution of cardiac output characteristic of normal pregnancy. Thus, the effect of pregnancy/ estradiol on any one vas...

journal_title：Seminars in perinatology

authors： Weiner CP,Thompson LP

更新日期：1997-10-01 00:00:00

abstract：:Late preterm infants (34-37 weeks gestation) pose unique challenges to physicians and nurses involved in their care after birth. They may be cared for in different units within hospitals after birth, including Neonatal Intensive Care Units, Newborn Nurseries, or rooming in with the mother. As a result of their gestati...

journal_title：Seminars in perinatology

authors： Laptook A,Jackson GL

更新日期：2006-02-01 00:00:00

abstract：:The unexpectedness of genital ambiguity in an infant creates an urgent and stressful situation. A logical approach, using a team of specialists together with nursery staff and physicians, allows each member to contribute expertise and unnecessary overlap of investigations. The psychological needs of the parents should...

journal_title：Seminars in perinatology

authors： McGillivray BC

更新日期：1992-12-01 00:00:00

abstract：:Up to half of all aortic dissections and ruptures in women younger than 40 years are associated with pregnancy. In pregnancy, women with aortic disease such as arteritis and aortitis are at significant risk of aneurysmal formation and dissection with potential for catastrophic outcomes. Pregnancy places predisposed wo...

journal_title：Seminars in perinatology

authors： Smok DA

更新日期：2014-08-01 00:00:00

abstract：:Transplant recipients are becoming pregnant with increasing frequency, and successful pregnancy outcomes have now been reported for women with all types of solid organ transplants. To prevent rejection of the transplanted organ, these patients are maintained on a life-long immunosuppressive regimen that must also be c...

journal_title：Seminars in perinatology

authors： Fuchs KM,Coustan DR

更新日期：2007-12-01 00:00:00

abstract：:The outcome literature on low birthweight (LBW) premature children indicates that they are at risk for a variety of neurodevelopmental impairments throughout childhood. To prevent such disabilities, numerous interventions have been initiated with LBW children. Nineteen intervention programs designed for LBW preterms t...

journal_title：Seminars in perinatology

authors： McCarton CM,Wallace IF,Bennett FC

更新日期：1995-08-01 00:00:00

abstract：:The placenta was classically considered a barrier, but in 1957 this notion was shattered. This organ is only a selective filter and metabolic site. In this review, the placental transfer of the top 17 substances of abuse are analyzed. In the National Library of Medicine only 41 papers that documented placental transfe...

journal_title：Seminars in perinatology

authors： Little BB,VanBeveren TT

更新日期：1996-04-01 00:00:00

abstract：:Candida is a leading cause of late onset infection (> 3 days of age) in the premature infant. Therefore, decisions about the diagnosis and management of infections caused by Candida are commonplace in the neonatal intensive care unit. Despite this fact, there are few comparative trials about treatment of neonatal Cand...

journal_title：Seminars in perinatology

authors： Bliss JM,Wellington M,Gigliotti F

更新日期：2003-10-01 00:00:00

abstract：:Diagnostic errors remain understudied in neonatology. The limited available evidence, however, suggests that diagnostic errors in the neonatal intensive care unit (NICU) result in significant and long-term consequences. In this narrative review, we discuss how the concept of diagnostic errors framed as missed opportun...

journal_title：Seminars in perinatology

authors： Shafer G,Singh H,Suresh G

更新日期：2019-12-01 00:00:00

abstract：:Following dramatic reductions between the early 1900s and the early 1980s, the maternal mortality ratio began to rise, reaching a peak of almost 17 maternal deaths per 100,000 live births. Although this number pales in comparison with that found in sub-Saharan Africa and India, the troubling rise in the United States ...

journal_title：Seminars in perinatology

authors： King JC

更新日期：2012-02-01 00:00:00

abstract：:Despite major advances in neonatal care, the burden of preterm birth remains high. This is not unexpected since strategies to identify and treat risk factors in early pregnancy have not been very effective in reducing the preterm birth rate. Initial studies suggested a potential benefit for 17-alpha-hydroxyprogesteron...

journal_title：Seminars in perinatology

authors： Caritis SN,Feghali MN,Grobman WA,Rouse DJ,Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal–Fetal Medicine Units Network.

更新日期：2016-08-01 00:00:00

abstract：:Cirrhosis and portal hypertension infrequently coincide with pregnancy but increase maternal and fetal morbidity and mortality when present. Chronic liver disease and portal hypertension are not contraindications to pregnancy but necessitate intensive monitoring throughout pregnancy. The complications of liver disease...

journal_title：Seminars in perinatology

authors： Russell MA,Craigo SD

更新日期：1998-04-01 00:00:00