The role of long chain polyunsaturated fatty acids in perinatal nutrition.

Abstract:

:The importance of omega-3 long chain polyunsaturated fatty acids in the perinatal period has been the focus of research for several decades. Infants born preterm miss out on the last trimester in utero transfer of omega-3 fatty acids and consequently have lower blood levels than infants born at term. Preterm infant formula was supplemented with the omega-3 docosahexaenoic acid and the omega-6 arachidonic acid from 2000 (to the level found in the breast milk of women consuming a western diet) based on trials reporting improvements in visual acuity. Docosahexaenoic acid supplementation beyond this level has not shown improvements in clinical or developmental outcomes, however the effect on childhood development in the most preterm infants remains to be resolved. Maternal omega-3 supplementation during pregnancy has the potential to reduce the incidence of preterm birth but may also, in some pregnancies, prolong gestation beyond term and increase fetal size.

journal_name

Semin Perinatol

journal_title

Seminars in perinatology

authors

Collins CT,Gibson RA,McPhee AJ,Makrides M

doi

10.1053/j.semperi.2019.06.004

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

151156

issue

7

eissn

0146-0005

issn

1558-075X

pii

S0146-0005(19)30082-5

journal_volume

43

pub_type

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