Neurodevelopmental outcome of extremely low-birth-weight infants randomly assigned to restrictive or liberal hemoglobin thresholds for blood transfusion.

abstract：:Down syndrome (DS) screening has been an integral part of routine prenatal screening for the last three decades. Recent efforts have been directed at developing additional non-invasive prenatal screening techniques that could not only improve sensitivity of prenatal screening, but also be employed in the first trimest...

journal_title：Seminars in perinatology

authors： Fuchs KM,Peipert JF

更新日期：2005-08-01 00:00:00

abstract：:The ductus arteriosus is a vital fetal structure designed to close shortly after birth. Although many physiologic and pharmacologic investigations have characterized the closure of this structure, genetic studies of persistent patency of the ductus arteriosus (patent ductus arteriosus, PDA) are relatively recent. Prog...

journal_title：Seminars in perinatology

authors： Hajj H,Dagle JM

更新日期：2012-04-01 00:00:00

abstract：:Abruptio placentae is an important cause of vaginal bleeding in the latter half of pregnancy. The key factor in the pathophysiology is hemorrhage at the decidual-placental interface. Small episodes may escape clinical detection, but severe grades impact significantly on fetal and maternal morbidity and mortality, with...

journal_title：Seminars in perinatology

authors： Hall DR

更新日期：2009-06-01 00:00:00

abstract：:Poor access to contraception can lead to several undesired health outcomes, including high rates of unintended pregnancy, high rates of teen pregnancy, spontaneous preterm delivery, preeclampsia and maternal death. Properly addressing these public health issues often require a coordinated response at the state governm...

journal_title：Seminars in perinatology

authors： Jackson AD,Sherpa ML

更新日期：2020-08-01 00:00:00

abstract：:Medical and psychological indications for lactation suppression are discussed, and methods for lactation suppression are evaluated. Medical indications for lactation suppression include 1) maternal anatomical abnormalities, such as inadequate secretory tissue and inverted nipples; 2) maternal breast infections and tu...

journal_title：Seminars in perinatology

authors： Harrison RG

更新日期：1979-07-01 00:00:00

abstract：:Neonatal hyperinsulinism (HI) is a clinical syndrome of pancreatic beta-cell dysfunction characterized by failure to suppress insulin secretion in the presence of hypoglycemia. Although rare, it is the most common cause for persistent hypoglycemia in the newborn period. Treatment can be extremely difficult, and partia...

journal_title：Seminars in perinatology

authors： Glaser B

更新日期：2000-04-01 00:00:00

abstract：:The developing heart undergoes a remarkable metabolic transformation as it adjusts to the higher-oxygen, extrauterine environment. During gestation, glycolysis and lactate oxidation constitute the major sources of adenosine triphosphate (ATP) for the fetal heart. After birth, however, there is a rapid shift from carbo...

journal_title：Seminars in perinatology

authors： Ascuitto RJ,Ross-Ascuitto NT

更新日期：1996-12-01 00:00:00

abstract：:The management of conjoined twins is complex and requires careful preparation. Pre-birth management includes prenatal counseling, which is important due to the overall poor prognosis. In instances of trial of life, the delivery must be tailored to address the anticipated anatomy based on prenatal imaging and anticipat...

journal_title：Seminars in perinatology

authors： C Sager E,Thomas A,C Sundgren N

更新日期：2018-10-01 00:00:00

abstract：:While the cesarean delivery (CD) rates have increased worldwide, operative vaginal delivery (OVD) rates continue to decline, with the United States having some of the lower rates amongst developed countries. It is clear that the use of forceps or vacuum can safely assist in accomplishing a vaginal delivery and prevent...

journal_title：Seminars in perinatology

authors： Gei AF

更新日期：2012-10-01 00:00:00

abstract：:There have been no controlled studies that clearly document a beneficial effect of TPN on neonatal mortality and morbidity. Beneficial effects such as reducing the time required to achieve some targeted weight and enhancing positive nitrogen balance are used in support of TPN. The positive opinion about TPN is strongl...

journal_title：Seminars in perinatology

authors： Gutcher G,Cutz E

更新日期：1986-07-01 00:00:00

abstract：:Transplant recipients are becoming pregnant with increasing frequency, and successful pregnancy outcomes have now been reported for women with all types of solid organ transplants. To prevent rejection of the transplanted organ, these patients are maintained on a life-long immunosuppressive regimen that must also be c...

journal_title：Seminars in perinatology

authors： Fuchs KM,Coustan DR

更新日期：2007-12-01 00:00:00

abstract：:Neonatal erythropoiesis is limited by a relatively inadequate production of erythropoietin. This is likely the result of dependence on the hepatic production of erythropoietin and an incomplete switchover to renal production. The present model of neonatal erythropoiesis suggests that the use of exogenous erythropoieti...

journal_title：Seminars in perinatology

authors： Doyle JJ

更新日期：1997-02-01 00:00:00

abstract：:Hydrops fetalis, a condition characterized by abnormal accumulation of fluid and edema in the fetus, is the final common pathway in a number of pathological conditions. The diagnosis of hydrops is based on ultrasonographic findings of generalized edema along with a serous effusion (ascites, pleural effusion, or perica...

journal_title：Seminars in perinatology

authors： Bullard KM,Harrison MR

更新日期：1995-12-01 00:00:00

abstract：:Prostaglandins PGE2, PGD2, PGI2, and PGF2 alpha, as well as thromboxanes and leukotrienes, are synthesized by the fetal and neonatal kidney. The major prostaglandin, PGE2, PGD2, and PGI2, increase RBF, free water clearance, urine flow, and natriuresis. Alterations in the synthetic and catabolic activity of renal prost...

journal_title：Seminars in perinatology

authors： Gleason CA

更新日期：1987-01-01 00:00:00

abstract：:Experience gathered over the last decade from high-risk centers provide strong evidence that mid-trimester sonographic markers are sensitive for Down syndrome prediction. More recent data indicate that combining mid trimester sonography with traditional serum markers significantly improves diagnostic accuracy over eit...

journal_title：Seminars in perinatology

authors： Bahado-Singh R,Cheng CC,Matta P,Small M,Mahoney MJ

更新日期：2003-04-01 00:00:00

abstract：:The safety of cesarean section has improved dramatically over the past 50 years. During the past 20 years a greater awareness of and discussion about the symptomatic morbidity that can result for women following vaginal delivery has occurred and women's expectations for the outcome of pregnancy for them and their babi...

journal_title：Seminars in perinatology

authors： Morrison J,MacKenzie IZ

更新日期：2003-02-01 00:00:00

abstract：:Classical and subtypes of kernicterus associated with bilirubin toxicity can be differentiated in part with physiological auditory measures that include auditory-evoked potentials and measures of cochlear integrity. The combination of these auditory measures suggests that bilirubin exposure results in auditory system ...

journal_title：Seminars in perinatology

authors： Shapiro SM,Popelka GR

更新日期：2011-06-01 00:00:00

abstract：:The primary methods currently in use for imaging the infant brain are cranial ultrasound (CUS), computed tomography (CT) and magnetic resonance imaging (MRI). This review outlines the relative strengths and weaknesses of these modalities in relation to the premature infant, with specific focus on the correlations betw...

journal_title：Seminars in perinatology

authors： Neil JJ,Inder TE

更新日期：2004-12-01 00:00:00

abstract：:Accurate assessment of fetal growth status requires the definition of an optimal standard, which represents the growth potential of the baby. Against this standard, individually 'customized' percentiles can be calculated. They improve the distinction between normal and abnormal, and help in our understanding and diagn...

journal_title：Seminars in perinatology

authors： Gardosi J

更新日期：2004-02-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs are frequently used during pregnancy (premature labor, polyhydramnios) and the immediate postnatal period (closure of patent ductus arteriosus). This article evaluates the renal effect of 3 nonspecific COX inhibitors (aspirin, indomethacin, and ibuprofen) in newborn rabbits. Five g...

journal_title：Seminars in perinatology

authors： Guignard JP

更新日期：2002-12-01 00:00:00

abstract：:Given the historically high rates of cesarean delivery in the United States, obstetrical providers must often consider an induction of labor for women with a history of prior cesarean delivery versus repeat cesarean delivery. Clinical evaluation of this scenario involves weighing the benefits of a successful trial of ...

journal_title：Seminars in perinatology

authors： Hoffman MK,Hunter Grant G

更新日期：2015-10-01 00:00:00

abstract：:Preeclampsia, intrauterine growth restriction (IUGR), and placental abruption are obstetrical conditions that constitute the syndrome of ischemic placental disease or IPD, the leading cause of indicated preterm birth and an important cause of neonatal morbidity and mortality. While the phenotypic manifestations vary s...

journal_title：Seminars in perinatology

authors： Friedman AM,Cleary KL

更新日期：2014-04-01 00:00:00

abstract：:Here we provide a brief overview of the natural process of labor and its biochemical, hormonal, and mechanical characteristics that can be exploited in methods employed for induction of labor. ...

journal_title：Seminars in perinatology

authors： Irani RA,Foster S

更新日期：2015-10-01 00:00:00

abstract：:Inhaled nitric oxide (iNO), a selective pulmonary vasodilator, is available for treatment of persistent pulmonary hypertension of the newborn in term and near-term neonates. iNO decreases pulmonary vascular resistance leading to diminished extrapulmonary shunt and also has a microselective effect which improves ventil...

journal_title：Seminars in perinatology

authors： Kinsella JP,Abman SH

更新日期：2000-12-01 00:00:00

abstract：:Clinically silent upper genital tract microbial infections have been strongly associated with spontaneous preterm delivery, especially prior to 32 weeks gestational age. This condition represents a potentially preventable or reversible cause of preterm birth using safe, readily available, and inexpensive antibiotics. ...

journal_title：Seminars in perinatology

authors： Andrews WW,Goldenberg RL,National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

更新日期：2003-06-01 00:00:00

abstract：:Up to the immediate past, and perhaps even to the present, a major difference between care of the fetus and of the neonate was the ability to examine directly the physical and biochemical traits of the unborn patient. In a span of time as short as perhaps 10 years it has become progressively possible to institute almo...

journal_title：Seminars in perinatology

authors： Manning FA

更新日期：1989-08-01 00:00:00

abstract：:For nearly 30 years the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network has been conducting randomized trials in pregnant women, many of which have changed clinical practice. Since 1986, the MFMU Network has conducted 29 randomized tr...

journal_title：Seminars in perinatology

authors： Thom EA,Rice MM,Saade GR,Reddy UM,Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal–Fetal Medicine Units Network.

更新日期：2016-08-01 00:00:00

abstract：:This article reviews the central role of nutrition in advancing the maternal, newborn, and child health agenda with a focus on evidence for effective interventions generated using randomized controlled trials in low- and middle-income countries (LMIC). The 1000 days spanning from conception to 2 years of life are a cr...

journal_title：Seminars in perinatology

authors： Christian P,Mullany LC,Hurley KM,Katz J,Black RE

更新日期：2015-08-01 00:00:00

abstract：:The ichthyoses encompass a variety of genetic disorders marked by abnormal epidermal differentiation. The neonatal period is critical for patients with ichthyosis because of the risk for significant associated morbidity and mortality, with the majority of complications arising as a result of impaired barrier function....

journal_title：Seminars in perinatology

authors： Craiglow BG

更新日期：2013-02-01 00:00:00

abstract：:Neonatal herpes simplex virus (HSV) infection is one of the life-threatening infections of newborns. It affects approximately 1,500 to 2,200 infants per year in the United States. Changes in the presentation of neonatal HSV infection over the past two decades include an increase in the frequency of skin, eye, and mout...

journal_title：Seminars in perinatology

authors： Jacobs RF

更新日期：1998-02-01 00:00:00