A systematic approach to the management of preterm labor.

Abstract:

:Preterm birth occurs in 7% to 12% of all deliveries, but accounts for over 85% of all perinatal morbidity and mortality. Although the ability of obstetric care providers to identify women at risk for preterm delivery has improved, the overall incidence of preterm birth has remained unchanged for the past 30 years. Preterm birth remains the single greatest challenge for physician-researchers in the field of maternal-fetal medicine in the 21st century. This article reviews in detail the current state of the literature as regards the etiology, pathophysiology, prevention, and treatment of premature labor and preterm birth. A better understanding of the molecular mechanisms responsible for the process of labor, both at term and preterm, will improve our ability to identify and manage women at risk of premature delivery.

journal_name

Semin Perinatol

journal_title

Seminars in perinatology

authors

Norwitz ER,Robinson JN

doi

10.1053/sper.2001.26417

keywords:

subject

Has Abstract

pub_date

2001-08-01 00:00:00

pages

223-35

issue

4

eissn

0146-0005

issn

1558-075X

pii

S0146-0005(01)80015-X

journal_volume

25

pub_type

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