A genetic approach to the child with sensorineural hearing loss.

abstract：:Unpublished results can bias biomedical literature, favoring positive over negative findings, primary over secondary analyses, and can lead to duplicate studies that unnecessarily endanger subjects and waste resources. The Neonatal Research Network's (NRN) publication policies for approving, reviewing, and tracking ab...

journal_title：Seminars in perinatology

authors： Archer SW,Carlo WA,Truog WE,Stevenson DK,Van Meurs KP,Sánchez PJ,Das A,Devaskar U,Nelin LD,Petrie Huitema CM,Crawford MM,Higgins RD,Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research

更新日期：2016-10-01 00:00:00

abstract：:Thyroid hormone plays an important role in regulating cardiovascular function during the transition to extrauterine physiology. Multiple mechanisms participate, ranging from transcriptional to more immediate nongenomic modes of regulation. ...

journal_title：Seminars in perinatology

authors： Portman MA

更新日期：2008-12-01 00:00:00

abstract：:In this review the factors present in human amniotic fluid that may function to inhibit bacterial growth have been examined. It appears that several potential antibacterial systems are present. Lysozyme and B-lysin may significantly contribute to the killing of gram-positive bacteria. Whether or not the remaining anti...

journal_title：Seminars in perinatology

authors： Schlievert P,Johnson W,Galask RP

更新日期：1977-01-01 00:00:00

abstract：:Hydrops fetalis, a condition characterized by abnormal accumulation of fluid and edema in the fetus, is the final common pathway in a number of pathological conditions. The diagnosis of hydrops is based on ultrasonographic findings of generalized edema along with a serous effusion (ascites, pleural effusion, or perica...

journal_title：Seminars in perinatology

authors： Bullard KM,Harrison MR

更新日期：1995-12-01 00:00:00

abstract：:Health care simulation is a powerful educational tool to help facilitate learning for clinicians and change their practice to improve patient outcomes and safety. To promote effective life-long learning through simulation, the educator needs to consider individuals, their experiences, and their environments. Effective...

journal_title：Seminars in perinatology

authors： Zigmont JJ,Kappus LJ,Sudikoff SN

更新日期：2011-04-01 00:00:00

abstract：:Invasive candidiasis (IC) is a leading cause of morbidity and mortality in preterm infants. Even if successfully treated, IC can cause significant neurodevelopmental impairment. Preterm infants are at increased risk for hematogenous Candida meningoencephalitis owing to increased permeability of the blood-brain barrier...

journal_title：Seminars in perinatology

authors： Tripathi N,Watt K,Benjamin DK Jr

更新日期：2012-12-01 00:00:00

abstract：:Concern over the influence of pregnancy-related alterations in hydration has prompted questions regarding the accuracy of using standard methods of determining body composition. We sought to investigate whether differences exist between body composition determined at 30 weeks and 39 weeks of gestation and postpartum, ...

journal_title：Seminars in perinatology

authors： Jaque-Fortunato SV,Khodiguian N,Artal R,Wiswell RA

更新日期：1996-08-01 00:00:00

abstract：:The importance of omega-3 long chain polyunsaturated fatty acids in the perinatal period has been the focus of research for several decades. Infants born preterm miss out on the last trimester in utero transfer of omega-3 fatty acids and consequently have lower blood levels than infants born at term. Preterm infant fo...

journal_title：Seminars in perinatology

authors： Collins CT,Gibson RA,McPhee AJ,Makrides M

更新日期：2019-11-01 00:00:00

abstract：:Ultrasound has permeated the practice of anesthesiology and is becoming an essential tool for the obstetric anesthesiologist in the labor and delivery suite. The most common applications include guidance for neuraxial (epidural and spinal) anesthesia and acute pain nerve blocks, as well as guidance for central and per...

journal_title：Seminars in perinatology

authors： Lee A

更新日期：2014-10-01 00:00:00

abstract：:Many infants with CDH can be managed with conventional mechanical ventilation and pharmacotherapy. However, some infants will require levels of ventilator support that are not compatible with survival. In these circumstances, extracorporeal membrane oxygenation (ECMO) has been used with varying results. The indication...

journal_title：Seminars in perinatology

authors： Khan AM,Lally KP

更新日期：2005-04-01 00:00:00

abstract：:This article reviews the literature on infectious diseases as a cause of stillbirth. Identifying a specific infection as a cause of stillbirth is limited by many obstacles. Nevertheless, "good faith" efforts estimate that approximately 9% to 15% of stillbirths are caused by infections. Infection may be especially impo...

journal_title：Seminars in perinatology

authors： Gibbs RS

更新日期：2002-02-01 00:00:00

abstract：:Nitric oxide (NO) is intimately involved in vascular homeostasis through its antiplatelet, antiproliferative, and vasodilating actions. Because of these beneficial properties, methods of harnessing NO for the prevention of vascular injury responses, such as intimal hyperplasia, are being explored. One such method invo...

journal_title：Seminars in perinatology

authors： Kibbe MR,Tzeng E

更新日期：2000-02-01 00:00:00

abstract：:The ductus arteriosus is a vital fetal structure designed to close shortly after birth. Although many physiologic and pharmacologic investigations have characterized the closure of this structure, genetic studies of persistent patency of the ductus arteriosus (patent ductus arteriosus, PDA) are relatively recent. Prog...

journal_title：Seminars in perinatology

authors： Hajj H,Dagle JM

更新日期：2012-04-01 00:00:00

abstract：:Pharmacotherapy, or medication-assisted treatment (MAT), is a critical component of a comprehensive treatment plan for the pregnant woman with opioid use disorder (OUD). Methadone and buprenorphine are two types of opioid-agonist therapy which prevent withdrawal symptoms and control opioid cravings. Methadone is a lon...

journal_title：Seminars in perinatology

authors： Rodriguez CE,Klie KA

更新日期：2019-04-01 00:00:00

abstract：:Long-term sequelae of preterm birth have been studied extensively up until the age of 5 to 8 years. However, the cognitive development of adolescents born preterm has received limited attention. The objective of this study is to determine school performance in adolescents born very preterm. We have followed up a cohor...

journal_title：Seminars in perinatology

authors： van de Bor M,den Ouden L

更新日期：2004-08-01 00:00:00

abstract：:Among risk factors for shoulder dystocia, a prior history of delivery complicated by shoulder dystocia is the single greatest risk factor for shoulder dystocia occurrence, with odds ratios 7 to 10 times that of the general population. Recurrence rates have been reported to be as high as 16%. Whereas prevention of shou...

journal_title：Seminars in perinatology

authors： Gurewitsch ED,Johnson TL,Allen RH

更新日期：2007-06-01 00:00:00

abstract：:Traditional birth attendants (TBAs) provided delivery care throughout the world prior to the development of organized systems of medical care. In 2016, an estimated 22% of pregnant women delivered with a TBA, mostly in rural or remote areas that lacked formal health services. Still active in many regions of LMICs, the...

journal_title：Seminars in perinatology

authors： Garces A,McClure EM,Espinoza L,Saleem S,Figueroa L,Bucher S,Goldenberg RL

更新日期：2019-08-01 00:00:00

abstract：:Candida is a leading cause of late onset infection (> 3 days of age) in the premature infant. Therefore, decisions about the diagnosis and management of infections caused by Candida are commonplace in the neonatal intensive care unit. Despite this fact, there are few comparative trials about treatment of neonatal Cand...

journal_title：Seminars in perinatology

authors： Bliss JM,Wellington M,Gigliotti F

更新日期：2003-10-01 00:00:00

abstract：:Tumors are a rare but important cause of mortality and morbidity in the neonate. There is a wide spectrum of benign and malignant tumors that can occur, some of which have a unique presentation and behavior in this age group. It is important to recognize that tumors such as stage IVS neuroblastoma, which have a good p...

journal_title：Seminars in perinatology

authors： Weitzman S,Grant R

更新日期：1997-02-01 00:00:00

abstract：:In mammals, a master circadian clock resides in the suprachiasmatic nuclei of the anterior hypothalamus. The suprachiasmatic nuclei is composed of multiple, single-cell circadian oscillators, which, when synchronized, lead to coordinated circadian outputs that ultimately regulate overt rhythms. Several "clock genes" h...

journal_title：Seminars in perinatology

authors： Reppert SM

更新日期：2000-08-01 00:00:00

abstract：:Late preterm infants (34-37 weeks postmenstrual age at birth) are intermediate between less mature preterm infants and infants born at 38 weeks or more in regard to autonomic brain stem maturation. Ventilatory responses to CO(2) in preterm infants born at 33 to 36 week are significantly higher than in infants born at ...

journal_title：Seminars in perinatology

authors： Hunt CE

更新日期：2006-04-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs are frequently used during pregnancy (premature labor, polyhydramnios) and the immediate postnatal period (closure of patent ductus arteriosus). This article evaluates the renal effect of 3 nonspecific COX inhibitors (aspirin, indomethacin, and ibuprofen) in newborn rabbits. Five g...

journal_title：Seminars in perinatology

authors： Guignard JP

更新日期：2002-12-01 00:00:00

abstract：:Retinopathy of Prematurity (ROP) is a preventable neovascular retinal disease with a lifetime impact on vision and ocular morbidities. Retinal vessel immaturity and oxygen therapy, influenced or modulated by several risk factors including oxidative stress, intermittent hypoxia and desaturations, inflammation, infectio...

journal_title：Seminars in perinatology

authors： Aranda JV,Qu J,Valencia GB,Beharry KD

更新日期：2019-10-01 00:00:00

abstract：:Clinically silent upper genital tract microbial infections have been strongly associated with spontaneous preterm delivery, especially prior to 32 weeks gestational age. This condition represents a potentially preventable or reversible cause of preterm birth using safe, readily available, and inexpensive antibiotics. ...

journal_title：Seminars in perinatology

authors： Andrews WW,Goldenberg RL,National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

更新日期：2003-06-01 00:00:00

abstract：:Experience gathered over the last decade from high-risk centers provide strong evidence that mid-trimester sonographic markers are sensitive for Down syndrome prediction. More recent data indicate that combining mid trimester sonography with traditional serum markers significantly improves diagnostic accuracy over eit...

journal_title：Seminars in perinatology

authors： Bahado-Singh R,Cheng CC,Matta P,Small M,Mahoney MJ

更新日期：2003-04-01 00:00:00

abstract：:While the cesarean delivery (CD) rates have increased worldwide, operative vaginal delivery (OVD) rates continue to decline, with the United States having some of the lower rates amongst developed countries. It is clear that the use of forceps or vacuum can safely assist in accomplishing a vaginal delivery and prevent...

journal_title：Seminars in perinatology

authors： Gei AF

更新日期：2012-10-01 00:00:00

abstract：:The principal objective of antenatal testing is to detect fetal hypoxia before the fetus has suffered lasting harm. This article summarizes some of the mechanisms by which fetal oxygen consumption is maintained under normal conditions, and adaptations that occur in response to hypoxemia. Alterations in the fetal heart...

journal_title：Seminars in perinatology

authors： Martin CB Jr

更新日期：2008-08-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) is a highly technical and complex method of life support. Patient and circuit emergencies on ECMO are rare, but in these cases, prompt and correct actions to address the crisis are needed to prevent morbidity and mortality. ECMO simulation programs have gained popularity in r...

journal_title：Seminars in perinatology

authors： Johnston L,Oldenburg G

更新日期：2016-11-01 00:00:00

abstract：:Use of immunosuppressants during pregnancy is indicated for anti-rejection therapy in transplantation patients and treatment of autoimmune diseases. Maternal side effects include nephrotoxocity and hepatotoxicity. All immunosuppressant drugs cross the placenta. Immunosuppressant use during the first trimester is not s...

journal_title：Seminars in perinatology

authors： Little BB

更新日期：1997-04-01 00:00:00

abstract：:Inhaled nitric oxide (iNO), a selective pulmonary vasodilator, is available for treatment of persistent pulmonary hypertension of the newborn in term and near-term neonates. iNO decreases pulmonary vascular resistance leading to diminished extrapulmonary shunt and also has a microselective effect which improves ventil...

journal_title：Seminars in perinatology

authors： Kinsella JP,Abman SH

更新日期：2000-12-01 00:00:00