Conducting research during the COVID-19 pandemic.

abstract：:The rapid evolution of the COVID-19 pandemic in New York City during the spring of 2020 challenged the Department of Obstetrics and Gynecology at Columbia University Irving Medical Center to rely on its core values to respond effectively. In particular, five core values, "5 C's," were engaged: Communication; Collabora...

journal_title：Seminars in perinatology

authors： Yates HS,Goffman D,D'Alton ME

更新日期：2020-10-01 00:00:00

abstract：:Preterm births account for a substantial portion of infant mortality, the major difference in mortality between African-American and white births in the United States, and the key reason that US infant mortality exceeds that of other developed nations. Although preterm birth rates are higher in the African-American co...

journal_title：Seminars in perinatology

authors： Hogue CJ,Hargraves MA

更新日期：1995-08-01 00:00:00

abstract：:Neonatal hyperbilirubinemia is a normal postnatal phenomenon resulting from a transitional imbalance between the production and elimination of bilirubin in the neonate. Bilirubin has been shown to be not only a potent antioxidant, but also toxic at excessive concentrations. As a result, the biology of bilirubin, its p...

journal_title：Seminars in perinatology

authors： Stevenson DK,Vreman HJ,Wong RJ,Contag CH

更新日期：2001-04-01 00:00:00

abstract：:This review documents and assesses recent trends in sudden infant death syndrome. We review medical literature, Internet resources, and national governmental data. A striking reduction in SIDS incidence of more than 50% has been observed in various countries after interventions, particularly during the early 1990s, to...

journal_title：Seminars in perinatology

authors： Ponsonby AL,Dwyer T,Cochrane J

更新日期：2002-08-01 00:00:00

abstract：:Late preterm infants (34-37 weeks gestation) pose unique challenges to physicians and nurses involved in their care after birth. They may be cared for in different units within hospitals after birth, including Neonatal Intensive Care Units, Newborn Nurseries, or rooming in with the mother. As a result of their gestati...

journal_title：Seminars in perinatology

authors： Laptook A,Jackson GL

更新日期：2006-02-01 00:00:00

abstract：PURPOSE:The purpose of this analysis was to determine the impact on specific forms of neonatal morbidity and mortality by allowing women to opt for delivery by elective cesarean section at 39 weeks of gestation (EGA). According to the National Vital Statistics Reports, over 70% of deliveries in the U.S. annually are at...

journal_title：Seminars in perinatology

authors： Hankins GD,Clark SM,Munn MB

更新日期：2006-10-01 00:00:00

abstract：:Experience gathered over the last decade from high-risk centers provide strong evidence that mid-trimester sonographic markers are sensitive for Down syndrome prediction. More recent data indicate that combining mid trimester sonography with traditional serum markers significantly improves diagnostic accuracy over eit...

journal_title：Seminars in perinatology

authors： Bahado-Singh R,Cheng CC,Matta P,Small M,Mahoney MJ

更新日期：2003-04-01 00:00:00

abstract：:In this article, we have reviewed the most common CNS abnormalities seen in perinatal medicine. The prognosis in ventriculomegaly is most closely related to the presence or absence of associated anomalies. The current treatment for DWM consists of shunting of either the posterior fossa cyst or lateral ventricles. Faci...

journal_title：Seminars in perinatology

authors： Paidas MJ,Cohen A

更新日期：1994-08-01 00:00:00

abstract：:Neuroblastoma is the most common malignant neoplasm occurring in the neonate and arguably the most variable in its presentation. This review examines differences in the tumor's clinical course in the context of known biologic determinants of behavior. Tumors that would go undetected except for prenatal ultrasonography...

journal_title：Seminars in perinatology

authors： Lukens JN

更新日期：1999-08-01 00:00:00

abstract：:The rapid rise of novel coronavirus disease 2019 (COVID-19) cases led the American Society for Reproductive Medicine (ASRM) to recommend immediate cessation of all new fertility treatment cycles on March 17, 2020. Controversial from the start, providers and patients expressed their opposition through online petitions,...

journal_title：Seminars in perinatology

authors： Gemmell LC,Williams Z,Forman EJ

更新日期：2020-11-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs are frequently used during pregnancy (premature labor, polyhydramnios) and the immediate postnatal period (closure of patent ductus arteriosus). This article evaluates the renal effect of 3 nonspecific COX inhibitors (aspirin, indomethacin, and ibuprofen) in newborn rabbits. Five g...

journal_title：Seminars in perinatology

authors： Guignard JP

更新日期：2002-12-01 00:00:00

abstract：:Prenatal diagnosis of fetal aneuploidy is a continuously and rapidly evolving area of research. Currently in the United States, the standard of care for screening pregnancies for aneuploidy involves assessment of maternal age together with the use of multiple second trimester maternal serum markers. This screening app...

journal_title：Seminars in perinatology

authors： Stewart TL,Malone FD

更新日期：1999-10-01 00:00:00

abstract：:Oligohydramnios is a severe and common complication of pregnancy. The finding of oligohydramnios can be associated with fetal anomalies, PROM, uteroplacental insufficiency (eg, growth retardation, postdatism, abruptio placenta, significant maternal illness), abnormalities of twinning, and idiopathic oligohydramnios. U...

journal_title：Seminars in perinatology

authors： McCurdy CM Jr,Seeds JW

更新日期：1993-06-01 00:00:00

abstract：:The importance of omega-3 long chain polyunsaturated fatty acids in the perinatal period has been the focus of research for several decades. Infants born preterm miss out on the last trimester in utero transfer of omega-3 fatty acids and consequently have lower blood levels than infants born at term. Preterm infant fo...

journal_title：Seminars in perinatology

authors： Collins CT,Gibson RA,McPhee AJ,Makrides M

更新日期：2019-11-01 00:00:00

abstract：:For nearly 30 years the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network has been conducting randomized trials in pregnant women, many of which have changed clinical practice. Since 1986, the MFMU Network has conducted 29 randomized tr...

journal_title：Seminars in perinatology

authors： Thom EA,Rice MM,Saade GR,Reddy UM,Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal–Fetal Medicine Units Network.

更新日期：2016-08-01 00:00:00

abstract：:Nuchal translucency (NT) describes an echo-free area, below the skin, in the posterior nuchal and back region of the fetus and is typically observed in the first and early second trimester of pregnancy. A wide NT has been correlated with chromosomal and congenital abnormalities in the fetus. An accurate NT measurement...

journal_title：Seminars in perinatology

authors： Abuhamad A

更新日期：2005-12-01 00:00:00

abstract：:This article reviews the literature on infectious diseases as a cause of stillbirth. Identifying a specific infection as a cause of stillbirth is limited by many obstacles. Nevertheless, "good faith" efforts estimate that approximately 9% to 15% of stillbirths are caused by infections. Infection may be especially impo...

journal_title：Seminars in perinatology

authors： Gibbs RS

更新日期：2002-02-01 00:00:00

abstract：:Neonatal herpes simplex virus (HSV) infection is one of the life-threatening infections of newborns. It affects approximately 1,500 to 2,200 infants per year in the United States. Changes in the presentation of neonatal HSV infection over the past two decades include an increase in the frequency of skin, eye, and mout...

journal_title：Seminars in perinatology

authors： Jacobs RF

更新日期：1998-02-01 00:00:00

abstract：:Here we provide a brief overview of the natural process of labor and its biochemical, hormonal, and mechanical characteristics that can be exploited in methods employed for induction of labor. ...

journal_title：Seminars in perinatology

authors： Irani RA,Foster S

更新日期：2015-10-01 00:00:00

abstract：:Understanding the role of ion channels in the generation of slow waves and action potentials in the myometrium is critical in designing strategies to regulate uterine contractile activity. The development of the patch clamp technique has allowed the identification of specific types of channels in the myometrium and pr...

journal_title：Seminars in perinatology

authors： Sanborn BM

更新日期：1995-02-01 00:00:00

abstract：:Retinopathy of Prematurity (ROP) is a preventable neovascular retinal disease with a lifetime impact on vision and ocular morbidities. Retinal vessel immaturity and oxygen therapy, influenced or modulated by several risk factors including oxidative stress, intermittent hypoxia and desaturations, inflammation, infectio...

journal_title：Seminars in perinatology

authors： Aranda JV,Qu J,Valencia GB,Beharry KD

更新日期：2019-10-01 00:00:00

abstract：:The studies described above collectively suggest that, whenever there is a decrease in fluid balance in the fetus, both fetal urine flow and tracheal secretion into the amniotic space are decreased. Conversely, when fetal hydration is increased, both urine and tracheal flows into the amniotic fluid may be increased. T...

journal_title：Seminars in perinatology

authors： Brace RA

更新日期：1986-04-01 00:00:00

abstract：:Thyroid hormone plays an important role in regulating cardiovascular function during the transition to extrauterine physiology. Multiple mechanisms participate, ranging from transcriptional to more immediate nongenomic modes of regulation. ...

journal_title：Seminars in perinatology

authors： Portman MA

更新日期：2008-12-01 00:00:00

abstract：:Preterm birth occurs in 7% to 12% of all deliveries, but accounts for over 85% of all perinatal morbidity and mortality. Although the ability of obstetric care providers to identify women at risk for preterm delivery has improved, the overall incidence of preterm birth has remained unchanged for the past 30 years. Pre...

journal_title：Seminars in perinatology

authors： Norwitz ER,Robinson JN

更新日期：2001-08-01 00:00:00

abstract：:Supplemental oxygen is often used as a life-saving therapy in the treatment of preterm infants. However, its protracted use can lead to the development of bronchopulmonary dysplasia (BPD), and more recently, has been associated with adversely affecting the general health of children and adolescents who were born prete...

journal_title：Seminars in perinatology

authors： Buczynski BW,Maduekwe ET,O'Reilly MA

更新日期：2013-04-01 00:00:00

abstract：:The future health of infants and children is dependent on the performance of clinical research in which infants participate. Achieving a proper balance between this social good and the obligation to protect infants who participate in research is a significant challenge. As investigators design and implement research p...

journal_title：Seminars in perinatology

authors： Diekema DS

更新日期：2009-12-01 00:00:00

abstract：:In mammals, a master circadian clock resides in the suprachiasmatic nuclei of the anterior hypothalamus. The suprachiasmatic nuclei is composed of multiple, single-cell circadian oscillators, which, when synchronized, lead to coordinated circadian outputs that ultimately regulate overt rhythms. Several "clock genes" h...

journal_title：Seminars in perinatology

authors： Reppert SM

更新日期：2000-08-01 00:00:00

abstract：:Surviving extremely low-birth-weight infants are at risk of severe neurodevelopmental disability. Transfusion with packed red cells is almost universal in the care of these infants, but the hemoglobin threshold at which these transfusions should be given is unclear. Different clinical trials of restrictive (low hemogl...

journal_title：Seminars in perinatology

authors： Whyte RK

更新日期：2012-08-01 00:00:00

abstract：:The intended and unintended effects of epidural labor analgesia are reviewed. Mothers randomized to epidural rather than parenteral opioid analgesia have better pain relief. Fetal oxygenation is not affected by analgesic method; however, neonates whose mothers received intravenous or intramuscular opioids rather than ...

journal_title：Seminars in perinatology

authors： Leighton BL,Halpern SH

更新日期：2002-04-01 00:00:00

abstract：:Ethics is an essential dimension of the management of periviable birth in both clinical practice and research. The goal of clinical care in periviable birth is to improve outcomes for current pregnant and fetal patients. The goal of research in periviable birth is to improve outcomes for future pregnant patients and f...

journal_title：Seminars in perinatology

authors： Chervenak FA,McCullough LB

更新日期：2013-12-01 00:00:00