当前位置： SCI文献检索 > JOURNAL OF ETHNOPHARMACOLOGY期刊下所有文献 > Activity of traditional South African sedative and potentially CNS-acting plants in the GABA-benzodiazepine receptor assay.

Activity of traditional South African sedative and potentially CNS-acting plants in the GABA-benzodiazepine receptor assay.

Abstract：

:Several plants are traditionally used to treat mental diseases in South Africa. Forty-six ethanol extracts from 35 species, both indigenous and exotic that are traditionally used predominantly as sedatives or to treat various CNS-related ailments were tested in the GABAA-benzodiazepine receptor-binding assay. In this assay, the binding of 3H-Ro 15-1788 (flumazenil) to the benzodiazepine site is measured. The GABAA-benzodiazepine receptor complex is involved in sedation, epilepsy and convulsions. Out of the 46 extracts tested, seven showed good activity and 10 showed moderate activity. The most active extracts were the ethanolic leaf extracts of Arctopus echinatus, Artemisa afra, four Helichrysum species and Mentha aquatica which all showed good dose-dependent activity.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Stafford GI,Jäger AK,van Staden J

doi

10.1016/j.jep.2005.04.004

keywords:

subject

Has Abstract

pub_date

2005-08-22 00:00:00

pages

210-5

issue

1-2

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(05)00257-6

journal_volume

100

pub_type

杂志文章

相关文献

JOURNAL OF ETHNOPHARMACOLOGY文献大全
  • Effects of Rubus coreanus on sperm parameters and cAMP-responsive element modulator (CREM) expression in rat testes.

    abstract：:Rubi Fructus (RF), the dried, unripe fruit of Rubus coreanus M IQ. (Rosaceae), has been used to improve male reproductive function in traditional Korean medicine. In this study, we investigated the effects of RF on sperm parameters and expression of cAMP-responsive element modulator (CREM), which has a crucial role in...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2007.08.025

    authors： Oh MS,Yang WM,Chang MS,Park W,Kim DR,Lee HK,Kim WN,Park SK

    更新日期：2007-12-03 00:00:00

  • Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan.

    abstract：AIM OF THE STUDY:The present investigation is an attempt to find out ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics. METHOD:We interviewed respondents in 30 remote sites of North-West Frontier Province by a structured interview form in the local language and respondent...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2010.01.052

    authors： Abbasi AM,Khan MA,Ahmad M,Zafar M,Jahan S,Sultana S

    更新日期：2010-03-24 00:00:00

  • Preventive effects of Ecliptae Herba extract and its component, ecliptasaponin A, on bleomycin-induced pulmonary fibrosis in mice.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Ecliptae Herba, a nourishing traditional Chinese medicine, is also a folk medicine for the treatment of lung diseases. AIM OF THE STUDY:To investigate the anti-fibrosis effects and the underlying mechanism of the extract of Ecliptae Herba and its potential active components. MATERIALS A...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2015.08.034

    authors： You XY,Xue Q,Fang Y,Liu Q,Zhang CF,Zhao C,Zhang M,Xu XH

    更新日期：2015-12-04 00:00:00

  • Effect of salvianolic-acid B on inhibiting MAPK signaling induced by transforming growth factor-β1 in activated rat hepatic stellate cells.

    abstract：AIM OF THE STUDY:Salvianolic-acid B (SA-B) is an effective component of Radix Salviae miltiorrhizae for anti-hepatic fibrotic herbs. MAPK signaling pathway has been implicated in hepatic stellate cells (HSC) stimulated by TGF-(1. We have investigated the effect of SA-B on MAPK pathway in rat HSC. MATERIALS AND METHODS...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2010.05.026

    authors： Lv Z,Song Y,Xue D,Zhang W,Cheng Y,Xu L

    更新日期：2010-11-11 00:00:00

  • The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice.

    abstract：:This study investigates anticonvulsant effects of an essential oil of the fruits of Pimpinella anisum (Umbelliferae), a folkloric remedy in the Iranian traditional medicine, against seizures induced by pentylenetetrazole (PTZ) or maximal electroshock (MES) in male mice. The essential oil suppressed tonic convulsions i...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(98)00161-5

    authors： Pourgholami MH,Majzoob S,Javadi M,Kamalinejad M,Fanaee GH,Sayyah M

    更新日期：1999-08-01 00:00:00

  • Antimalarial actions of Lawsonia inermis, Tithonia diversifolia and Chromolaena odorata in combination.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Chromolaena odorata, Tithonia diversifolia and Lawsonia inermis are medicinal plants used in treating malaria in traditional medicine system. Previous studies however showed that their dichloromethane, methanol (1:1) extracts were more active against Plasmodium parasite than the aqueous e...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2016.06.045

    authors： Afolayan FID,Adegbolagun OM,Irungu B,Kangethe L,Orwa J,Anumudu CI

    更新日期：2016-09-15 00:00:00

  • Effect of Acanthopanax senticosus stem on mast cell-dependent anaphylaxis.

    abstract：:We studied the effect of Acanthopanax senticosus stem (ACPS) on mast cell-dependent anaphylaxis. ACPS inhibited compound 48/80-induced systemic anaphylaxis at a dose of 1.0 g/kg by 50%. ACPS also inhibited passive cutaneous anaphylaxis reaction and histamine release from mast cells in a dose-dependent manner, respecti...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(01)00403-2

    authors： Yi JM,Hong SH,Kim JH,Kim HK,Song HJ,Kim HM

    更新日期：2002-03-01 00:00:00

  • Investigation of association of chemical profiles with the tracheobronchial relaxant activity of Chinese medicinal herb Beimu derived from various Fritillaria species.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Fritillariae Bulbus (Beimu in Chinese) is derived from the bulbus of many Fritillaria species (family Liliaceae), which has been used as an antitussive herb in traditional Chinese medicine for more than 2000 years. Due to the complexity of plant origins and significant variations in chemi...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.08.027

    authors： Wu X,Chan SW,Ma J,Li P,Shaw PC,Lin G

    更新日期：2018-01-10 00:00:00

  • Sauropus androgynus L. Merr.-A phytochemical, pharmacological and toxicological review.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Sauropus androgynus L. Merr is an underexploited perennial shrub traditionally used as a medicinal plant in South Asia and Southeast Asia. The plant is regarded as not just a green vegetable for diet, but as a traditional herb for certain aliments. For instance, it has traditionally been ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2020.112778

    authors： Zhang BD,Cheng JX,Zhang CF,Bai YD,Liu WY,Li W,Koike K,Akihisa T,Feng F,Zhang J

    更新日期：2020-07-15 00:00:00

  • Apigenin attenuates TGF-β1-stimulated cardiac fibroblast differentiation and extracellular matrix production by targeting miR-155-5p/c-Ski/Smad pathway.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Apigenin is a natural flavonoid compound present in chamomile (Matricaia chamomilla L.) from the Asteraceae family, which is used in the treatment of cardiovascular diseases by traditional healers, but its effects on differentiation and extracellular matrix (ECM) production of cardiac fib...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113195

    authors： Wang F,Fan K,Zhao Y,Xie ML

    更新日期：2021-01-30 00:00:00

  • Phytochemical profiles and biological activity evaluation of Zanthoxylum bungeanum Maxim seed against asthma in murine models.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Zanthoxylum bungeanum Maxim seed (ZBMS) has been used in Traditional Chinese Medicine (TCM) as an ingredient of polyherbal formulations for the treatment of inflammation and asthma. The aim of this study was to analyze the major composition and to evaluate the anti-asthma activity of ZBMS...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2014.01.013

    authors： Tang W,Xie Q,Guan J,Jin S,Zhao Y

    更新日期：2014-03-28 00:00:00

  • Antimicrobial activity of certain Indian medicinal plants used in folkloric medicine.

    abstract：:Fifty medicinal plants belonging to 26 families were studied for their antimicrobial activity. Among 50 plants tested, 72% showed antimicrobial activity. About 22 plant extracts from 15 families exhibited activity against both Gram-positive and Gram-negative bacteria. Fourteen plants belonging to 11 families did not s...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(00)00345-7

    authors： Srinivasan D,Nathan S,Suresh T,Lakshmana Perumalsamy P

    更新日期：2001-03-03 00:00:00

  • UPLC-MS-based serum metabolomics reveals protective effect of Ganoderma lucidum polysaccharide on ionizing radiation injury.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Ganoderma lucidum Polysaccharide (GLP),traditional Chinese medicine (TCM) active ingredient, has a long history and has good curative effects on radiation injury. However, the mechanism of GLP treating radiation injury has not been clearly elucidated. THE AIM OF THE STUDY:This study was ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.112814

    authors： Yu C,Fu J,Guo L,Lian L,Yu D

    更新日期：2020-08-10 00:00:00

  • Puerarin attenuates glutamate-induced neurofilament axonal transport impairment.

    abstract：AIM OF THE STUDY:Puerarin (Pur) is a primary component of the most functional extracts of Pueraria lobata used in traditional Chinese medicine for centuries. Since it has been postulated that Pur protects the brain against glutamate (Glu) neurotoxicity, we investigated the effects of Pur on Glu-induced axonal transport...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2010.08.005

    authors： Zhou J,Wang H,Xiong Y,Li Z,Feng Y,Chen J

    更新日期：2010-10-28 00:00:00

  • Efficacy and short-term safety of topical Dwarf Elder (Sambucus ebulus L.) versus diclofenac for knee osteoarthritis: A randomized, double-blind, active-controlled trial.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Sambucus ebulus L. (S. ebulus) has had long-standing application in Traditional Persian Medicine for joint pain and for a variety of bone and joint disorders. According to traditional use of S. ebulus and its relevant pharmacologic properties, this study was designed to evaluate the effic...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jep.2016.04.035

    authors： Jabbari M,Hashempur MH,Razavi SZ,Shahraki HR,Kamalinejad M,Emtiazy M

    更新日期：2016-07-21 00:00:00

  • Inhibition of Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells by Phyllanthus urinaria extracts.

    abstract：AIM OF THE STUDY:Helicobacter pylori is linked to a majority of peptic ulcers and to some types of gastric cancer, and its resistance to antibiotic treatment is now found worldwide. This study is aimed at evaluating the antimicrobial activity of Phyllanthus urinaria Linnea (Euphorbiaceae), chloroform (PUC) and methanol...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2008.05.022

    authors： Lai CH,Fang SH,Rao YK,Geethangili M,Tang CH,Lin YJ,Hung CH,Wang WC,Tzeng YM

    更新日期：2008-08-13 00:00:00

  • Pharmacokinetics comparative study of a novel Chinese traditional herbal formula and its compatibility.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Da Chuan Xiong Decoction Compound preparation (DCXDCP), the formulation of a classical Chinese prescription recorded in "Xuanminglunfang", was clinically employed to treat migraine's disease. AIM OF THE STUDY:In order to investigate the influence of compatibility on the pharmacokinetics ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.05.007

    authors： Zheng Q,Yue PF,Wu B,Hu PY,Wu ZF,Yang M

    更新日期：2011-09-01 00:00:00

  • Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice.

    abstract：:The effects of daily administration of Withania somnifera root extract (1.4 g/kg body wt.) and Bauhinia purpurea bark extract (2.5 mg/kg body wt.) for 20 days on thyroid function in female mice were investigated. While serum triiodothyronine (T3) and thyroxine (T4) concentrations were increased significantly by Bauhin...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(99)00018-5

    authors： Panda S,Kar A

    更新日期：1999-11-01 00:00:00

  • High hepatic exposure of furanocoumarins in Radix Angelica dahuricae is associated with transporter mediated active uptake.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Radix Angelica dahuricae (RAD), the roots of Angelica dahurica (Hoffm.) Benth. & Hook.f. ex Franch. & Sav, is a well-known traditional Chinese medicine (TCM) and has been used for centuries to treat headaches, toothaches, nose congestion, abscesses, furunculoses, and acne. This herb is al...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.10.014

    authors： Chen L,Yang H,Yu C,Yuan M,Li H

    更新日期：2018-02-15 00:00:00

  • Are meta-analyses of Chinese herbal medicine trials trustworthy and clinically applicable? A cross-sectional study.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Meta-analysis (MA) on Chinese herbal medicine (CHM) trials is increasingly published and indexed in major international databases but their trustworthiness and clinical applicability is uncertain. We aimed to assess the characteristics and methodological quality of MA on CHM. MATERIALS A...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2014.12.028

    authors： Chung VC,Ho RS,Wu X,Fung DH,Lai X,Wu JC,Wong SY

    更新日期：2015-03-13 00:00:00

  • (2S)-naringenin from Typha angustata inhibits vascular smooth muscle cell proliferation via a G0/G1 arrest.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Typha angustata is used in traditional Chinese medicine for a variety of clinical disorders. Its pharmacological actions include beneficial effects on hyperlipidemia and myocardial infarction, as well as labor-inducing and antibacterial effects. AIM OF THE STUDY:We investigated the mecha...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.12.038

    authors： Lee JJ,Yi H,Kim IS,Kim Y,Nhiem NX,Kim YH,Myung CS

    更新日期：2012-02-15 00:00:00

  • Cytotoxicity and modes of action of five Cameroonian medicinal plants against multi-factorial drug resistance of tumor cells.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Beilschmiedia acuta Kosterm, Clausena anisata (Willd) Hook, Fagara tessmannii Engl., Newbouldia laevis Seem., and Polyscias fulva (Hiern) Harms. are medicinal plants used in Cameroonian traditional medicine in the treatment of various types of cancers. The present study aims at investigat...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2014.02.025

    authors： Kuete V,Tankeo SB,Saeed ME,Wiench B,Tane P,Efferth T

    更新日期：2014-04-11 00:00:00

  • Rosmarinus officinalis L. hydroalcoholic extract, similar to fluoxetine, reverses depressive-like behavior without altering learning deficit in olfactory bulbectomized mice.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Rosemary, Rosmarinus officinalis L., has several therapeutic applications in folk medicine for the treatment of a wide range of diseases, including depression. AIM OF THE STUDY:To evaluate the ability of Rosmarinus officinalis hydroalcoholic extract (ROHE), as compared to the positive cont...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2012.06.017

    authors： Machado DG,Cunha MP,Neis VB,Balen GO,Colla AR,Grando J,Brocardo PS,Bettio LE,Dalmarco JB,Rial D,Prediger RD,Pizzolatti MG,Rodrigues AL

    更新日期：2012-08-30 00:00:00

  • Anti-Candida activity of Brazilian medicinal plants.

    abstract：:Essential oils and ethanolic extracts from the leaves and/or roots of 35 medicinal plants commonly used in Brazil were screened for anti-Candida albicans activity. The oils were obtained by water-distillation using a Clevenger-type system. Essential oils from 13 plants showed anti-Candida activity, including Aloysia t...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2004.11.016

    authors： Duarte MC,Figueira GM,Sartoratto A,Rehder VL,Delarmelina C

    更新日期：2005-02-28 00:00:00

  • Insight into the inhibitory effects of Zanthoxylum nitidum against Helicobacter pylori urease and jack bean urease: Kinetics and mechanism.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Zanthoxylum nitidum (Roxb.) DC. is a traditional Chinese medicine characterised by anti-inflammatory and anti-Helicobacter pylori, which is widely used to treat H. pylori-induced gastric disease in China. However, the underlying mechanism related to its anti-H. pylori activity remains unc...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2019.112419

    authors： Lu Q,Li C,Wu G

    更新日期：2020-03-01 00:00:00

  • Antimycobacterial activity of Citrullus colocynthis (L.) Schrad. against drug sensitive and drug resistant Mycobacterium tuberculosis and MOTT clinical isolates.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Citrullus colocynthis (Cucurbitaceae), a folk herbal medicine and traditionally used natural remedy for tuberculosis in India has been studied to validate its antitubercular activity against drug sensitive and drug resistant (including multidrug resistant) Mycobacterium tuberculosis and M...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2013.06.022

    authors： Mehta A,Srivastva G,Kachhwaha S,Sharma M,Kothari SL

    更新日期：2013-08-26 00:00:00

  • Application of radioligand receptor binding assays in the search for CNS active principles from Chinese medicinal plants.

    abstract：:Extracts of Schefflera bodinieri and S. delavayi (Araliaceae), Celastrus angulatus and C. orbiculatus (Celastraceae), Clerodendrum mandarinorum and C. bungei (Verbenaceae), Periploca callophylla and P. forrestii (Asclepiadaceae), Alangium platanifolium (Alangiaceae) and Uncaria rhynchophylla (Rubiaceae) were assessed ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(96)01454-7

    authors： Zhu M,Bowery NG,Greengrass PM,Phillipson JD

    更新日期：1996-11-01 00:00:00

  • Antibacterial activity of Brazilian propolis and fractions against oral anaerobic bacteria.

    abstract：:Propolis collected from a cerrado area in Minas Gerais State, Brazil, was subjected to chromatography on silica gel column and to partition between immiscible solvents. Propolis aqueous-ethanolic extract and fractions obtained were tested for inhibitory activity against periodontitis-causing bacteria. All of the assay...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(02)00003-x

    authors： Santos FA,Bastos EM,Uzeda M,Carvalho MA,Farias LM,Moreira ES,Braga FC

    更新日期：2002-04-01 00:00:00

  • The knowledge of medicinal plants in Africa today.

    abstract：:The oral tradition for communication in Africa is stressed as well as the secrecy of the treatments with plants by traditional medicine-men. This makes it difficult to obtain more exact information on all the different aspects of traditional medicine. Nevertheless, some data have been collected in the Francophone coun...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(80)90022-7

    authors： Lantum DN

    更新日期：1980-03-01 00:00:00

  • Triterpenoid saponins from Ilex cornuta protect H9c2 cardiomyocytes against H2O2-induced apoptosis by modulating Ezh2 phosphorylation.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Ilex cornuta Lindl. et Paxt. (Aquifoliaceae family) belongs to the Ilex genus. The leaves of this plant are used for the popular herbal tea "Ku-Ding-Cha" in China due to their health benefits for sore throat, obesity and hypertension. Our previous studies have shown that the extract of Il...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113691

    authors： Yu D,Zhu Z,Wang M,Ding X,Gui H,Ma J,Yan Y,Li G,Xu Q,Wang W,Mao C

    更新日期：2021-04-06 00:00:00