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Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice.

Abstract：

:The effects of daily administration of Withania somnifera root extract (1.4 g/kg body wt.) and Bauhinia purpurea bark extract (2.5 mg/kg body wt.) for 20 days on thyroid function in female mice were investigated. While serum triiodothyronine (T3) and thyroxine (T4) concentrations were increased significantly by Bauhinia, Withania could enhance only serum T4 concentration. Both the plant extracts showed an increase in hepatic glucose-6-phosphatase (G-6-Pase) activity and antiperoxidative effects as indicated either by a decrease in hepatic lipid peroxidation (LPO) and/or by an increase in the activity of antioxidant enzyme(s). It appears that these plant extracts are capable of stimulating thyroid function in female mice.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Panda S,Kar A

doi

10.1016/s0378-8741(99)00018-5

keywords:

subject

Has Abstract

pub_date

1999-11-01 00:00:00

pages

233-9

issue

2

eissn

0378-8741

issn

1872-7573

pii

S0378874199000185

journal_volume

67

pub_type

杂志文章

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