Abstract:
:Phyllanthus maderaspatensis (whole plant extracts) was evaluated for its antihepatotoxic and choleretic activities in rats. The plant extracts (200 mg/kg, n-hexane, ethyl alcohol or water) showed a remarkable hepatoprotective activity against acetaminophen-induced hepatotoxicity as judged from the serum marker enzymes. The water and ethyl alcohol extracts showed moderate activity compared to the n-hexane extract, which showed activity at a dose as low as 1.5 mg/kg. The antihepatotoxicity of the hexane extract was found to be better than silymarin, a standard hepatoprotective herbal drug. The effect of n-hexane extract was found to be concentration-dependent. This extract also exhibited choleretic activity in normal rats, and in vitro hydroxyl radical scavenging activity and inhibition of lipid peroxidation.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Asha VV,Akhila S,Wills PJ,Subramoniam Adoi
10.1016/j.jep.2004.02.005keywords:
subject
Has Abstractpub_date
2004-05-01 00:00:00pages
67-70issue
1eissn
0378-8741issn
1872-7573pii
S0378874104000674journal_volume
92pub_type
杂志文章abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The decoction prepared from the roots of Pelargonium endlicherianum Fenzl. has been used for the treatment of gastrointestinal parasitism in small ruminants in Turkish Folk Medicine. AIM OF THE STUDY:The aim of the present study is to investigate in vitro anthelmintic activity of the ext...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2016-07-01 00:00:00
abstract::Himatanthus lancifolius, popularly known as "agoniada" in Brazil, is largely used in folk medicine against asthma, dysmenorrhea and as an emenagogue and abortive. This study reveals the effects of an alkaloid rich fraction (AlkF) obtained from the bark of Himatanthus lancifolius in vascular and non-vascular smooth mus...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2005-09-14 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Waltheria indica L. is traditionally used in several countries against inflammatory related diseases and cancer, mainly as a decoction of the aerial parts. AIM OF THE STUDY:The transcription factor NF-κB is known to induce tumor promotion and progression and is considered a major player ...
journal_title:Journal of ethnopharmacology
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更新日期:2017-05-05 00:00:00
abstract::The purpose of this study was to characterize the putative anxiolytic-like activity of an ethanolic extract prepared from the leaves of Apocynum venetum (AV) using the elevated plus maze (EPM) in mice. Male C75BL/6 mice were either treated orally with the AV extract or the positive controls diazepam and buspirone, res...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2007-04-04 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Lilhocarpus polystachys Rehd. (Sweet Tea, ST) is a folk herbal medicine that has been traditionally used as a natural remedy for hypertension in China, whose mechanism remains unveiled. Flavonoid fraction is considered as the major active components in ST. This study aimed to provide expe...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2012.06.016
更新日期:2012-09-28 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Arctium lappa and Tussilago farfara (Asteraceae) are two plant species used traditionally as antitubercular remedies. The aim of this study was (i) to screen Arctium lappa and Tussilago farfara extracts for activity against Mycobacterium tuberculosis and (ii) to isolate and identify the c...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2014-08-08 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Propolis has been employed extensively in many cultures since ancient times as antiseptic, wound healing, anti-pyretic and others due to its biological and pharmacological properties, such as immunomodulatory, antitumor, anti-inflammatory, antioxidant, antibacterial, antiviral, antifungal...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2019.112174
更新日期:2019-12-05 00:00:00
abstract::The present study evaluated the effect of green tea (Camellia sinensis L.) leaf extract on triglyceride and glucose homeostasis in a fructose-fed hypertriglyceridemic, insulin-resistant hamster model. There was a significant decrease in plasma triglyceride levels following supplementation of the green tea epigallocate...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2006-03-08 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2009-04-21 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Labisia pumila var. alata (LPva) is a traditional medicinal herb used by Malaysian women to treat many ailments of the genitourinary tract. Its phytoestrogenic properties suggest potential to prevent recurrent urinary tract infection (UTI) in women post menopause. The aim of this study wa...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2011-06-14 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
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更新日期:2021-01-30 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:India being a multicultural nation, every region of the country offers a distinct culinary flavor and taste. These flavors are attributed to spices and condiments which form the mainstay of Indian cuisine. Most of these spices and condiments are derived from various biodiversity hotspots ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2018.02.001
更新日期:2018-06-12 00:00:00
abstract::The aqueous extract of the tuber of Smilax china L., popularly known in China as "jin gang ten", was tested for its anti-inflammatory activities in rats by egg-albumin-induced edema and anti-nociceptive effects in mice using hot-plate test and acetic acid-induced abdominal constriction test, respectively. The aqueous ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2005.08.004
更新日期:2006-02-20 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Kanglaite (KLT) is an active extract of the Coix lacryma-jobi seed, which can benefit Qi and nourish Yin, and disperse the accumulation of evils. It is used as a biphasic broad-spectrum anti-cancer drug, and shows synergistic effects with radiotherapy and chemotherapy. However, the mechan...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2020.113388
更新日期:2021-01-10 00:00:00
abstract::Recent trends in research into African medicinal plants show that while ethnobotanical surveys continue, there is an appreciable increase in research activity in the area of bioactivity of natural products. The biological areas most researched include antimicrobial, molluscicidal, toxicity tests and antitumour in decr...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/0378-8741(93)90017-y
更新日期:1993-03-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:There is limited evidence about the role of herbal and traditional medicine in pregnancy-related insomnia. Extant documents on traditional Persian medicine refer to many plants which could induce sleep and which were used by pregnant women. In Iran, local herbal shops continue to provide ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jep.2018.08.001
更新日期:2018-12-05 00:00:00
abstract::The knowledge and skills of Ethiopian traditional healers in Gondar region on the pharmaceutical aspects of their practice were assessed using a questionnaire. Of the 86 healers interviewed, only 83 gave responses good enough to be considered in the analysis of results. It was shown that the healers obtained their dru...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(84)90094-1
更新日期:1984-06-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Ling-Gui-Zhu-Gan Decoction (LGZGD) formula, derived from traditional Chinese medicine (TCM), has definitive clinical efficacy in the treatment of heart failure (HF) in China. However, little is known of the underlying mechanism of LGZGD. AIM OF THE STUDY:The aim of this work was to inves...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2020-03-25 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2014-09-11 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2015-11-04 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2018-08-10 00:00:00
abstract::An aqueous decoction of the root bark of Uapaca nitida Müll-Arg. is currently used locally at the Benedictine Mission at Peramiho in Tanzania to treat malaria. We have now demonstrated that extracts of root bark and leaves of this tree are active against the multidrug-resistant K1 strain of Plasmodium falciparum in vi...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(93)90088-m
更新日期:1993-09-01 00:00:00
abstract::Traditional medicine used in Central Anatolia; Ankara, Kayseri, Niğde and south-eastern parts of Karaman and Konya provinces have been studied. Two hundred and ninety one folk remedies obtained from 103 plant species belonging to 40 families and 4 animal species are reported with their vernacular names, parts used, me...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2001-05-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Harungana madagascariensis Lam. ex Poir. (Hypericaceae) is used in folk medicine to treat a variety of human ailments, mainly antibacterial, antifungal, antiviral and viral infections. In the present study, the methanol extract from the leaves (HML) and bark (HMB) of this plant as well as...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.06.005
更新日期:2016-08-22 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Calotropis gigantea R.Br. (Asclepiadaceae) is a perennial undershrub found chiefly in wastelands throughout India. It has been reported as a traditional folkloric medicine for a variety of alignments. The plant Calotropis gigantea is also used in some parts of India for wound healing in c...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2009-08-17 00:00:00
abstract::The use of herbal medicine in Jordan is very common. In order to evaluate the knowledge and the attitudes of the herbalists and acquire the common and less common medicinal herbs sold by the Jordanian herbalists, more than 100 herbalists throughout the country were interviewed and data concerning herbs present in thei...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:There is a lack of systematic descriptions and characterization of strokes and their effects in both the cerebral hippocampus and cortex. Shuxuetong (SXT) injection was reported to have good therapeutic effects in the clinic; therefore, it was selected as a drug intervention method for cerebral ischemia repa...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Lithospermum erythrorhizon, a naphthoquinone compound derived from a shikonin, has long been used as traditional Chinese medicine for treatment of various diseases, including cancer. To evaluate the cytotoxic effects of shikonin on AGS gastric cancer cells via induction of cell cycle arre...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2013.11.055
更新日期:2014-02-12 00:00:00
abstract::Fifty medicinal plants belonging to 26 families were studied for their antimicrobial activity. Among 50 plants tested, 72% showed antimicrobial activity. About 22 plant extracts from 15 families exhibited activity against both Gram-positive and Gram-negative bacteria. Fourteen plants belonging to 11 families did not s...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2001-03-03 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Ligusticum chuanxiong Hort. (Umbelliferae), a traditional Chinese medicinal herb, is often prescribed together with nitric oxide donors for treating coronary heart diseases such as angina in China; however, studies concerning their pharmacological interaction are scarce. AIM OF THE STUDY...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2009.01.002
更新日期:2009-03-18 00:00:00