Abstract:
:The aqueous extract of the tuber of Smilax china L., popularly known in China as "jin gang ten", was tested for its anti-inflammatory activities in rats by egg-albumin-induced edema and anti-nociceptive effects in mice using hot-plate test and acetic acid-induced abdominal constriction test, respectively. The aqueous extract in the dose of 1000 mg/kg (i.g.) had a significant anti-nociceptive and anti-inflammatory effect compared to physiological saline. The anti-inflammatory effects are similar to acetylsalicylic acid (200 mg/kg, i.g.). We also evaluated the aqueous extract for the inhibition of prostaglandin production (for COX-2 inhibitions) in lipopolysaccharide (LPS)-induced mouse macrophage cells. The result showed that both COX-2 activity and COX expression were inhibited by the extract. These active extracts suppressing activities warranted further studies of active principles and development of new anti-inflammatory and analgesic agents. Studies to determine correlation between chemical composition and pharmacological activity are underway.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Shu XS,Gao ZH,Yang XLdoi
10.1016/j.jep.2005.08.004keywords:
subject
Has Abstractpub_date
2006-02-20 00:00:00pages
327-32issue
3eissn
0378-8741issn
1872-7573pii
S0378-8741(05)00506-4journal_volume
103pub_type
杂志文章abstract::Murdannia bracteata has been used as a Taiwanese folk medicine for its anti-inflammatory properties. However, neither its active ingredients nor its anti-inflammatory actions are well defined. Nitric oxide (NO), overproduced by activated macrophages via inducible NO synthase (iNOS), is suggested to be a significant pa...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2007.02.025
更新日期:2007-06-13 00:00:00
abstract::Thirty four crude extracts of Panamanian plants, from nine species of Celastraceae and Lamiaceae, were assayed for xanthine oxidase (XO) inhibitory activity. The enzymatic activity was estimated by measuring the increase in absorbance at 290 nm due to uric acid formation. Eighty five percent of the crude extracts were...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(95)01225-3
更新日期:1995-04-01 00:00:00
abstract::A combination of spices (Piper nigrum, Piper longum and Zingiber officinale), herbs (Cyperus rotundus and Plumbago zeylanica) and salts make up Amrita Bindu. The study was focused to evaluate the antioxidant property of individual ingredients in Amrita Bindu against the free radical 2,2'-azinobis-(3-ethylbenzothiazoli...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2005.09.043
更新日期:2006-04-21 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Enslaved Africans in the Americas had to reinvent their medicinal flora in an unknown environment by adhering to plants that came with them, learning from Amerindians and Europeans, using their Old World knowledge and trial and error to find substitutes for their homeland herbs. This proc...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2012.08.008
更新日期:2012-10-11 00:00:00
abstract::The present study was planned to investigate the ethnoveterinary methods practiced by the owners of pneumatic-cart pulling camels in Faisalabad Metropolis (Pakistan). During a 7-year-period (November 1992-November 1999), 200 owners of draught camels working in the city were interviewed. Information concerning the ethn...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2004.11.008
更新日期:2005-02-28 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Postmenopausal osteoporosis is the most common bone disease worldwide. Information concerning the effects of herbal medicines on mesenchymal cell osteogenesis and senescence remains lacking. AIM OF THIS STUDY:This study was designed to investigate the effects of Du-Huo-Ji-Sheng-Tang (DHJ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.12.011
更新日期:2017-02-23 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Korean red ginseng (Panax ginseng C.A. Meyer, Araliaceae) has been historically used as a traditional drug for the prevention and treatment of most ageing-related diseases, such as obesity, dyslipidemia, diabetes, and cardiovascular disease. Elderly men with testosterone deficiency are st...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2017.08.032
更新日期:2018-01-10 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Ocimum species are traditionally used for the treatment of anxiety, nerve pain, convulsions and a variety of neurodegenerative disorders. The present study was undertaken to evaluate the anti-amnesic effect of O. basilicum L., O. sanctum L. and O. gratissimum L. extracts using in-vitro an...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.10.026
更新日期:2016-12-04 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In Persian ethnomedicine several herbal remedies and functional foods have been used to treat migraine headache which are mostly summarized in Qarabadin-e-kabir (Aghili-Shirazi MH, 1773). One of them is Citron syrup (Sharbat-e-Balang) containing edible Citrus medica L. fruit juice and sug...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jep.2015.12.040
更新日期:2016-02-17 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The root of Scutellaria baicalensis Georgi, also called Huangqin in China, is an herbal-based nutraceutical which is usually used in Chinese medicated diet (CMD). As an abundant ingredient in Huangqin, wogonoside is a flavonoid glycoside. The present work investigated the anti-inflammator...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2013.04.025
更新日期:2013-06-21 00:00:00
abstract::Acyl-coenzyme A: cholesterol acyltransferase (ACAT) esterifies free cholesterol in the liver and the intestine. It has relations with production of lipoproteins and accumulation of cholesteryl esters of the atheroma. Therefore, ACAT inhibitors may act as antihypercholesterolemic and antiatherosclerotic agents. One iso...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2006.10.012
更新日期:2007-04-04 00:00:00
abstract::Ginseng, Panax ginseng C.A. Meyer, is a well-known Chinese traditional medicine. There have been more than 300 original papers in Chinese and in English during the last 10 years in China. This review paper summarizes some achievements from some of these published papers. Twenty-eight ginsenosides and some minor consti...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/0378-8741(92)90057-x
更新日期:1992-02-01 00:00:00
abstract:ETHNO-PHARMACOLOGICAL RELEVANCE:Picrosides I, II and apocynin are the main active principles present in the roots and rhizomes of Picrorhiza kurroa Royle ex. Benth (Kutki). Ethno-medicinally, the plant is used for the treatment of liver, upper respiratory tract disorders and dyspepsia, since long in Ayurveda. AIM OF T...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.07.072
更新日期:2017-02-02 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Uncaria tomentosa (Willd.) DC (Rubiaceae) is a species native to the Amazon rainforest and surrounding tropical areas that is endowed with immunomodulatory properties and widely used around the world. In this study we investigated the immunomodulatory potential of Uncaria tomentosa (UT) a...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2011.06.021
更新日期:2011-09-01 00:00:00
abstract::When bradykinin-induced contraction of the isolated rat ileum was tested in the presence of Aloe barbadensis Mill. (Liliaceae) gel (fraction F-1) and with the fraction obtained by precipitation of the F-1 with 55% ammonium sulfate (F-55), the maximal responses to bradykinin were reduced by 10 and 22%, respectively. Fu...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2004.03.030
更新日期:2004-07-01 00:00:00
abstract:AIM OF THE STUDY:The present study was an ethnobotanical survey of three Local Government areas of the Ijebu area of Ogun State in southwest Nigeria for plants used in the treatment of measles. MATERIALS AND METHODS:Unstructured interviews were conducted among both urban and rural dwellers of three major groups of Ije...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2009.01.004
更新日期:2009-03-18 00:00:00
abstract::As significant contributors to the generation, dissemination and publication of scientific knowledge, graduate students have considerable leverage on publication trends and the future direction of ethnopharmacology. The rigid discipline-oriented framework of academia is often cited as responsible for impeding interdis...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2011.01.053
更新日期:2011-04-12 00:00:00
abstract::Withering's (1741-1799) greatest merit is not so much that of having discovered the therapeutic value of foxglove in hydropsy, since this indication (among others) was already part of traditional medicine, but actually during a decade of carefully recording clinical observations, he authoritatively settled definite gu...
journal_title:Journal of ethnopharmacology
pub_type: 历史文章,杂志文章
doi:10.1016/0378-8741(91)90109-q
更新日期:1991-04-01 00:00:00
abstract::The aqueous extract of Nigella sativa (N. sativa) was investigated for anti-inflammatory, analgesic and antipyretic activities in animal models. The extract has an anti-inflammatory effect demonstrated by its inhibitory effects on Carrageenan induced paw edema. It also produced significant increase in the hot plate re...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(01)00216-1
更新日期:2001-06-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Xiao-Xu-Ming decoction (XXMD) has long been employed clinically to treat stroke in traditional Chinese Medicine. AIM OF THE STUDY:To investigate the neuroprotective effects of XXMD in vivo and in vitro stroke models and determine involved mechanisms. MATERIALS AND METHODS:Two models (fo...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2009.09.054
更新日期:2010-01-08 00:00:00
abstract::The organic extracts of leaves and roots of five plants used for treating malaria in Central, Nairobi and Rift Valley Provinces, Kenya were tested for brine shrimp lethality and in vitro antiplasmodial activity against chloroquine sensitive and resistant strains of Plasmodium falciparum. Of the plants tested, 60% were...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2003.09.047
更新日期:2004-01-01 00:00:00
abstract::The essential oil of Pulicaria odora, a Moroccan medicinal plant; was analyzed by GC-MS, and subjected to column chromatography on silica gel. Two major constituents were isolated and identified as 2-isopropyl-4-methylphenol (1) and isobutyric acid 2-isopropyl-4-methylphenylester (2), by analysis of spectroscopic data...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2005.02.015
更新日期:2005-06-03 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The present study has indicated phytochemical composition, distribution and ethno-medicinal uses of Arnebia euchroma (Royle) I.M. Johnst, which is commonly known as "Ratanjot" in the Indian subcontinent. It has widely been used in the traditional systems of the Unani, Ayurvedic and Chines...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/j.jep.2021.113896
更新日期:2021-01-29 00:00:00
abstract::Cecropia obtusifolia (Cecropiaceae) is a species from tropical America and its leaves are used in traditional medicine for the treatment of diabetes and as an anti-inflammatory agent. In the present study, the analgesic, anti-inflammatory and central nervous system depressant effects of the aqueous extract from the le...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(01)00253-7
更新日期:2001-08-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Waltheria indica L. is traditionally used in several countries against inflammatory related diseases and cancer, mainly as a decoction of the aerial parts. AIM OF THE STUDY:The transcription factor NF-κB is known to induce tumor promotion and progression and is considered a major player ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2017.03.048
更新日期:2017-05-05 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Propolis has long been used as a popular folk medicine due to its wide spectrum of alleged biological and pharmaceutical properties. In Chile, propolis is widely used by folklore medicine as an anti-inflammatory agent; however, this property has not been demonstrated by scientific methods...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2015.03.050
更新日期:2015-06-20 00:00:00
abstract::The effects of daily administration of Withania somnifera root extract (1.4 g/kg body wt.) and Bauhinia purpurea bark extract (2.5 mg/kg body wt.) for 20 days on thyroid function in female mice were investigated. While serum triiodothyronine (T3) and thyroxine (T4) concentrations were increased significantly by Bauhin...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(99)00018-5
更新日期:1999-11-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The role of Azadirachta indica (neem) against Chagas disease and its antibiotic and antidiabetic action have been demonstrated in non-pregnant animals. However, the effects of neem on lipid metabolism and oxidative stress during pregnancy remain to be investigated. The objective of this s...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2012.07.023
更新日期:2012-10-11 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Coptidis Rhizoma has been used to treat diabetes mellitus for more than 1400 years in China. Berberine, one of the main alkaloids of Coptidis Rhizoma, is a principal antidiabetic component of Coptidis Rhizoma. To investigate the effects of berberine on impaired neurogenic contractility of...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2013.10.039
更新日期:2013-12-12 00:00:00
abstract::Several pharmacologic studies were carried out with an aqueous extract of Rhigiocarya racemifera after phytochemical tests revealed the main constituents to be glycosides, saponins and tannins. Studies on intact mice showed that the extract has an intraperitoneal LD50 of 142 mg/kg and that 50 mg/kg of the extract redu...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(86)90151-0
更新日期:1986-02-01 00:00:00