Abstract：
:As the Mycobacterium tuberculosis strains resistant to multiple drugs are increasing at an alarming rate, there is an urgent need for alternative anti-tuberculosis drugs. In a bioassay-guided search for antimycobacterial compounds obtained from higher plants, the study of the hexane extract from the aerial parts of Lantana hispida was performed and the biological activity of the plant products were tested against Mycobacterium tuberculosis H37Rv strain by microdilution alamar blue assay. Activity of the primary fractions led to the isolation of three pentacyclic triterpenoids with oleanane nucleous, together with beta-sitosterol. The molecular structures of the compounds were characterized as 3-acetoxy-22-(2'-methyl-2Z-butenyloxy)-12-oleanen-28-oic acid (1), 3-hydroxy-22 beta-(2'-methyl-2Z-butenoyloxy)-12-oleanen-28-oic acid (reduced lantadene A) (2) and oleanolic acid (3). MIC values for compounds 1 and 2 were 50 microg/ml, and for compound 3 the MIC=25 microg/ml.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Jiménez-Arellanes A,Meckes M,Torres J,Luna-Herrera Jdoi
10.1016/j.jep.2006.11.033subject
Has Abstractpub_date
2007-05-04 00:00:00pages
202-5issue
2eissn
0378-8741issn
1872-7573pii
S0378-8741(06)00594-0journal_volume
111pub_type
杂志文章abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The rhizomes of Kaempferia parviflora Wall. ex Baker have been traditionally used in Thailand to treat abscesses, gout, and peptic ulcers. AIM:Previously, we reported that the chloroform fraction of a Kaempferia parviflora extract had an inhibitory effect on rat paw-edema. In the present...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2011.01.013
更新日期：2011-07-14 00:00:00
abstract：:A pharmacological screening was conducted on 101 methanolic extracts from 31 medicinal plants chosen among the more widely used plants in Rwandese traditional medicine. Twenty four extracts from 13 plants have shown spasmolytic properties, while 35 extracts from 15 plants contain spasmodic active principles. Ten extra...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(84)90053-9
更新日期：1984-12-01 00:00:00
abstract：:Extracts of several Southern African plants which have been used in folk remedies have been prepared, and the extracts were tested in a variety of experimental tumour test-systems. Raphionacme hirsuta and Cheilanthes contracta have been used in African anticancer medicines. Extracts of these plants showed antitumor ac...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(80)81014-2
更新日期：1980-12-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Tryptanthrin is a compound isolated from Polygonum tinctorium, which is a known folk medicine with various biological activities. AIM OF THE STUDY:Allergic diseases are initiated by the development of allergen-specific T helper type 2 (Th2) cells and amplified by the degranulation of and...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2010.12.041
更新日期：2011-03-24 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Nervilia plicata (Orchidaceae) has long been used in the antidiabetic medicinal preparations of traditional healers of Wayanad (Kerala), but recuperative potential of the plant was remained undefined. We demonstrated the regenerative potential of the plant extract on kidney affected by ty...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2010.10.025
更新日期：2011-01-27 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Antrodia camphorata (AC) is well known in Taiwan as a traditional Chinese medicinal fungus. However, the anticancer activity of AC against human HER-2/neu-overexpressing ovarian cancers is poorly understood. MATERIALS AND METHODS:The aim of this study is to investigate whether a submerge...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.04.023
更新日期：2013-06-21 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Tuberculosis (TB) is one of the leading causes of morbidity and mortality globally. The disease is especially important because of increasing drug resistant strains and co infection with human immune virus (HIV) and acquired immune disease syndrome (AIDS). Because of this there is need to...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.12.020
更新日期：2014-02-03 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:: This study involves the assessment of the Bhutanese traditional medicine (BTM) which was integrated with the mainstream biomedicine in 1967 to provide primary health care services in the country. It caters to 20-30% of the daily out-patients within 49 traditional medicine units attached...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.04.030
更新日期：2013-06-21 00:00:00
abstract：AIM OF THE STUDY:Leishmaniasis, caused by protozoan from Leishmania genus, is an endemic disease in the tropical and subtropical regions of the world. The chemotherapy to this disease is not always effective and can cause several side effects. Chenopodium ambrosioides L. (Chenopodiaceae) is used by the native people in...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2007.10.009
更新日期：2008-01-17 00:00:00
abstract：:Four taxoids (taxusin, baccatin VI, baccatin III and 1beta-hydroxybaccatin I) and five lignans (lariciresinol, taxiresinol, 3'-demethylisolariciresinol-9'-hydroxyisopropylether, isolariciresinol and 3-demethylisolariciresinol) were isolated from the heartwood of Taxus baccata L. (Taxaceae) growing in Turkey through ch...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2003.09.005
更新日期：2003-12-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Sri Lanka has rich traditional systems of medicine, which cater to 60-70% of the rural population׳s primary health care needs. However, development of existing systems has been hindered by the unavailability of up-to-date information on medicinal materials and other related issues. For st...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.06.016
更新日期：2014-08-08 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Abelmoschus manihot (L.) medic (AM) is a natural medicinal plant used for the treatment of inflammatory diseases in China. Huangkui capsule (HKC), an extract from AM, has been proved clinically effective in improving renal inflammation and glomerular injury in chronic kidney disease (CKD)...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.03.006
更新日期：2013-05-20 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The Renshen Shouwu capsule (RSSW) is a patented Traditional Chinese Medicine (TCM), that has been proven to improve memory and is widely used in China to apoplexy syndrome and memory deficits. To investigate the neuroprotective and therapeutic effect of the Renshen Shouwu standardized ext...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2015.02.027
更新日期：2015-05-13 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The genus Eucomis (Hyacinthaceae) consists of 10 species that are extensively used in African traditional medicine. This review is an appraisal of current information on the distribution and morphology, traditional uses, pharmacology, toxicology and approaches devised to enhance the conse...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2013.11.002
更新日期：2014-01-01 00:00:00
abstract：:Contraceptive activity and the correlated endocrine alterations of an aqueous extract of the leaves of Dieffenbachia amoena were investigated. In female Wistar rats the extract, given for 4 days during the estrous cycle, induced significant variations of luteinizing hormone (LH), follicle-stimulating hormone (FSH), pr...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(84)90059-x
更新日期：1984-12-01 00:00:00
abstract：UNLABELLED:ETHNOPHARMACOLOGICAL CONTEXT: A detailed review of the ethnobotany and commercial history of Pelargonium sidoides is presented, together with a brief summary of pre-clinical and clinical scientific results that support the use of the plant in modern, evidence-based phytomedicines. The aim is to identify the ...
journal_title：Journal of ethnopharmacology
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.jep.2008.07.037
更新日期：2008-10-28 00:00:00
abstract：:A total of 260 extracts have been prepared from 75 medicinal plant species collected in Africa, Panama and Mauritius. Three different concentrations of each extract have been screened in vitro for cytotoxic activity using a colorimetric assay to determine cell survival of human colon carcinoma Co115 cells. Fifteen pla...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(88)90006-2
更新日期：1988-07-01 00:00:00
abstract：:The oleoresin from Brazilian Copaifera species yielded copalic acid and sesquiterpenes and showed marked anti-inflammatory activity using various experimental models in rats. The oleoresin significantly inhibited carrageenin-induced pedal edema following oral doses from 0.70 to 2.69 ml/kg, but was somewhat less effect...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(88)90235-8
更新日期：1988-01-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Curcuma mangga Valeton & Van Zijp. (Zingiberaceae family) contains curcuminoids and diterpenes which have anti-inflammatory effect. In traditional use, the elixir of this plant has been used to detoxify the poisonous plants, treatment of gastric ulcer, chest pain, fever, skin disease and ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2019.111828
更新日期：2019-06-28 00:00:00
abstract：:Studies performed with Opuntia streptacantha sap in three different animal species using several experimental conditions are described. The Opuntia sap induced hypoglucemic effects when orally administered to intact animals under induced states of moderate increase of blood sugar. In normoglucemic and pancreatectomize...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(83)90019-3
更新日期：1983-03-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Labisia pumila var. alata (LPva) is a traditional medicinal herb used by Malaysian women to treat many ailments of the genitourinary tract. Its phytoestrogenic properties suggest potential to prevent recurrent urinary tract infection (UTI) in women post menopause. The aim of this study wa...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2011.04.018
更新日期：2011-06-14 00:00:00
abstract：:Tribulus terrestris L. (Zygophyllaceae) have been used as an aphrodisiac both in the Indian and Chinese traditional systems of medicine. Administration of Tribulus terrestris extract (TT) increased sexual behaviour and intracavernous pressure both in normal and castrated rats and these effects were probably due to the...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2004.08.030
更新日期：2005-01-04 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Poincianella pyramidalis (Tul.) LP Queiroz (Fabaceae) is an endemic tree in the Northeast of Brazil. Its flowers, leaves, stem bark and root have been used over the years to treat infections, abdominal pain, inflammation, diarrhea, heartburn, and dyspepsia. AIM OF THE STUDY:The present s...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2020.113181
更新日期：2021-01-10 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:While scorpionism is not a serious public health problem in Spain, traditional Spanish knowledge has retained a large number of plant-based and animal-based remedies for scorpion stings. Additionally, this arthropod plays an important role in the treatment of its own sting and has become ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2012.12.033
更新日期：2013-03-07 00:00:00
abstract：:A herbal tea (called an abafado in Brazil) prepared from the dried leaves of lemongrass was administered to healthy volunteers. Following a single dose or 2 weeks of daily oral administration, the abafado produced no changes in serum glucose, urea, creatinine, cholesterol, triglycerides, lipids, total bilirubin, indir...
journal_title：Journal of ethnopharmacology
pub_type： 临床试验,杂志文章
doi：10.1016/0378-8741(86)90074-7
更新日期：1986-07-01 00:00:00
abstract：:This review explores medieval, ancient and modern sources for ethnopharmacological uses of Ficus (fig) species, specifically for employment against malignant disease and inflammation. The close connection between inflammatory/infectious and cancerous diseases is apparent both from the medieval/ancient merging of these...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2008.06.025
更新日期：2008-09-26 00:00:00
abstract：AIM OF THE STUDY:To evaluate in vitro the antiprotozoal and cytotoxic activities of 80% methanol extract from 45 medicinal plants collected in Sankuru (Democratic Republic of Congo) against Trypanosoma brucei brucei, Trypanosoma cruzi and the chloroquine-sensitive Ghanaian strain of Plasmodium falciparum, and MRC-5 cel...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2007.10.028
更新日期：2008-02-12 00:00:00
abstract：ETHNOPHARMACOLOGICAL IMPORTANCE:Gastrointestinal disorders and infections are the major pathoaetiologies of diarrhoea causing many problems in human health and animal production. Many Combretum species are used in traditional medicine to treat infectious diseases including diarrhoea and many other ailments by rural peo...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.03.030
更新日期：2014-06-11 00:00:00
abstract：:Strychnos henningsii Gilg is used in African traditional medicine for the treatment of various ailments, including rheumatism, gastrointestinal complaints and snake bites. Different preliminary pharmacological experiments are described. The results show that some of the reported folk medicinal applications of S. henni...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(91)90045-f
更新日期：1991-09-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Lepidium meyenii (Maca) is traditionally employed in the Andean region for its supposed fertility benefits. This study investigated the effect of Maca on the serum pituitary hormone levels during the pro-oestrus phase. MATERIALS AND METHODS:Maca powder was made from the tubers of Lepidiu...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.11.058
更新日期：2014-02-03 00:00:00
