Antineoplastic constituents of some Southern African plants.

Abstract:

:Extracts of several Southern African plants which have been used in folk remedies have been prepared, and the extracts were tested in a variety of experimental tumour test-systems. Raphionacme hirsuta and Cheilanthes contracta have been used in African anticancer medicines. Extracts of these plants showed antitumor activity in some rodent test-systems, but the results were not confirmed. In the folk-lore, Haemanthus natalensis has been used in emetics and Urginea capitata preparations have been used to vaccinate African chiefs. Extracts of these plants showed significant cytotoxicity in the KB cell culture test-system. Infusions of Brunsvigia radulosa have been used as folk remedies for abdominal troubles. An extract of this Amaryllis plant increased the life span of P-388 leukaemic mice. Amaryllis bellandonna has also been investigated. Extracts of Amaryllis belladonna had to be fractionated in order to produce significant antitumour activity in the P-388 lymphocytic leukaemia test-system.

journal_name

J Ethnopharmacol

authors

Charlson AJ

doi

10.1016/s0378-8741(80)81014-2

subject

Has Abstract

pub_date

1980-12-01 00:00:00

pages

323-35

issue

4

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(80)81014-2

journal_volume

2

pub_type

杂志文章
  • A review of the traditional use of southern African medicinal plants for the treatment of fungal skin infections.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Human dermatophyte infections are one of the most common classes of infection globally, with an estimated 1.7 billion people contracting at least one infection annually. Southern African ethnic groups used multiple plants to treat dermatophytosis and to alleviate the symptoms, yet the ant...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2019.112539

    authors: Cock IE,Van Vuuren SF

    更新日期:2020-04-06 00:00:00

  • Drug leads from the Kallawaya herbalists of Bolivia. 1. Background, rationale, protocol and anti-HIV activity.

    abstract::Aqueous, organic and alcoholic extracts of over 100 samples of 60 species of Kallawaya medicinal herbs representing 30 plant families were assayed to compare their toxicity and ability to protect MT-2 T-lymphoblastoid cells from the cytopathic effect of human immunodeficiency virus (HIV). The results are reported as a...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(96)01380-3

    authors: Abdel-Malek S,Bastien JW,Mahler WF,Jia Q,Reinecke MG,Robinson WE Jr,Shu Y,Zalles-Asin J

    更新日期:1996-03-01 00:00:00

  • Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats.

    abstract::The protective effect of Anacardium occidentale aqueous extract against streptozotocin-induced diabetes was evaluated in rats. The rats were treated with 175 mg/kg of the extract per os, twice daily; beginning 2 days before streptozotocin (STZ) injection. A total of 3 days after STZ administration, there was a 48% inc...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(97)00159-1

    authors: Kamtchouing P,Sokeng SD,Moundipa PF,Watcho P,Jatsa HB,Lontsi D

    更新日期:1998-09-01 00:00:00

  • Screening of some Indian medicinal plants for their antimicrobial properties.

    abstract::A total of 82 Indian medicinal plants traditionally used in medicines were subjected to preliminary antibacterial screening against several pathogenic and opportunistic microorganisms. Aqueous, hexane and alcoholic extracts of each plant were tested for their antibacterial activity using agar well diffusion method at ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(98)00055-5

    authors: Ahmad I,Mehmood Z,Mohammad F

    更新日期:1998-09-01 00:00:00

  • Folk medical uses of plant foods in southern Appalachia, United States.

    abstract::An analysis of information obtained from interviews with 660 older native inhabitants of the southern Appalachian region in the United States indicates that plant foods, especially cultivars and materials processed from them, and some wildcrafted plant foods as well, constituted the bulk of the folk materia medica in ...

    journal_title:Journal of ethnopharmacology

    pub_type: 历史文章,杂志文章

    doi:10.1016/j.jep.2006.04.008

    authors: Cavender A

    更新日期:2006-11-03 00:00:00

  • Banana (Musa spp) from peel to pulp: ethnopharmacology, source of bioactive compounds and its relevance for human health.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Banana is a fruit with nutritional properties and also with acclaimed therapeutic uses, cultivated widely throughout the tropics as source of food and income for people. Banana peel is known by its local and traditional use to promote wound healing mainly from burns and to help overcome o...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2014.11.008

    authors: Pereira A,Maraschin M

    更新日期:2015-02-03 00:00:00

  • The taste of heat: How humoral qualities act as a cultural filter for chemosensory properties guiding herbal medicine.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Organoleptic properties, and more specifically chemosensory cues, have been shown to guide therapeutic applications of medicinal plants. Humoral qualities, on the other hand, are widely believed to be an abstract concept, mainly applied post hoc to validate therapy. However, the nexus bet...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.01.027

    authors: Geck MS,Cabras S,Casu L,Reyes García AJ,Leonti M

    更新日期:2017-02-23 00:00:00

  • Triterpenoids from the genus Gynostemma: Chemistry and pharmacological activities.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:G. pentaphyllum, also known as Jiao-Gu-Lan, has been used traditionally as folk remedies for many diseases, including diabetes mellitus, metabolic syndrome, aging, and neurodegenerative diseases in China and some countries in East and Southeast Asia. It is considered as an "immortality he...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2020.113574

    authors: Nguyen NH,Ha TKQ,Yang JL,Pham HTT,Oh WK

    更新日期:2021-03-25 00:00:00

  • Prevention of experimental diabetes by Uncaria tomentosa extract: Th2 polarization, regulatory T cell preservation or both?

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Uncaria tomentosa (Willd.) DC (Rubiaceae) is a species native to the Amazon rainforest and surrounding tropical areas that is endowed with immunomodulatory properties and widely used around the world. In this study we investigated the immunomodulatory potential of Uncaria tomentosa (UT) a...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2011.06.021

    authors: Domingues A,Sartori A,Golim MA,Valente LM,da Rosa LC,Ishikawa LL,Siani AC,Viero RM

    更新日期:2011-09-01 00:00:00

  • Inhibitory effects of 1-O-methyl-fructofuranose from Schisandra chinensis fruit on melanogenesis in B16F0 melanoma cells.

    abstract:AIM OF THE STUDY:1-O-methyl-fructofuranose (1-O-MFF) from the fruit of Schisandra chinensis is a traditional Korean medicinal herb that has a variety of beneficial properties. The effect of purified 1-O-MFF on melanogenesis including the activation of related signaling pathways was investigated. MATERIALS AND METHODS:...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2010.08.010

    authors: Oh EY,Jang JY,Choi YH,Choi YW,Choi BT

    更新日期:2010-10-28 00:00:00

  • Antihypertensive action of a procyanidin glycoside from Rhamnus lycioides.

    abstract::The antihypertensive action of a procyanidin glycoside isolated from Rhamnus lycioides aerial parts was studied in spontaneously and renal hypertensive rats. This compound, like 20 micrograms/kg i.v. of captopril, produced a very clear in vivo inhibition of angiotensin I converting enzyme when given at a dose of 3 mg/...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(91)90149-8

    authors: Terencio MC,Sanz MJ,Paya M

    更新日期:1991-01-01 00:00:00

  • Acute toxicity, antinociceptive activity and indole alkaloids of aqueous extract from bark of Aspidosperma cuspa (Kunth) Blake.

    abstract:UNLABELLED:ETNOPHARMACOLOGICAL RELEVANCE: Aspidosperma cuspa (Kunth) Blake (Apocynaceae) is popularly known as "amargosa" or "cuspa", and its bark is used in folk medicine primarily for pain. AIM OF THE STUDY:In the present study the acute toxicity, antinociceptive effect and alkaloids of the aqueous decoction extract...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2012.07.021

    authors: Pérez NM,Torrico FB,Morales A

    更新日期:2012-09-28 00:00:00

  • Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice.

    abstract::Administration of Withania somnifera extract (Solanaceae) was found to significantly reduce leucopenia induced by cyclophosphamide (CTX) treatment. The total WBC count on the 12th day of the CTX-treated group was 3720 cells/mm3 and that of CTX along with Withania was 6120 cells/mm3. Treatment of Withania along with CT...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(98)00039-7

    authors: Davis L,Kuttan G

    更新日期:1998-10-01 00:00:00

  • Plumeria rubra L.- A review on its ethnopharmacological, morphological, phytochemical, pharmacological and toxicological studies.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Plumeria rubra L. (Apocynaceae) is a deciduous, commonly ornamental, tropical plant grown in home premises, parks, gardens, graveyards, because of its beautiful and attractive flowers of various colours and size. The different parts of the plant are used traditionally to treat various dis...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2020.113291

    authors: Bihani T

    更新日期:2021-01-10 00:00:00

  • Salvia miltiorrhiza Bunge (Danshen) extract attenuates permanent cerebral ischemia through inhibiting platelet activation in rats.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Danshen is a crude herbal drug isolated from dried roots of Salvia miltiorrhiza Bunge. This plant is widely used in oriental medicine for the treatment of cardiovascular and cerebrovascular diseases. The supercritical CO2 extract from Danshen (SCED) (57.85%, 5.67% and 4.55% for tanshinone...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.06.023

    authors: Fei YX,Wang SQ,Yang LJ,Qiu YY,Li YZ,Liu WY,Xi T,Fang WR,Li YM

    更新日期:2017-07-31 00:00:00

  • The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model.

    abstract::Paeoniflorin and sinomenine, derived from the root of Paeonia lactiflora Pall. (family Ranunculaceae) and the stem of Sinomenium acutum Rehder & Wilson (family Menispermaceae), respectively, have been, and are currently, widely used for treatment of rheumatic and arthritic diseases in China and Japan. Our previous stu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2005.08.020

    authors: Chan K,Liu ZQ,Jiang ZH,Zhou H,Wong YF,Xu HX,Liu L

    更新日期:2006-02-20 00:00:00

  • Mechanisms involved in the gastroprotective activity of Celtis iguanaea (Jacq.) Sargent on gastric lesions in mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Celtis iguanaea (Canabaceae) is popularly known as esporão-de-galo, stands out among the medicinal plants used for treatment of gastric ulcers. In Brazil, the leaves they are used traditionally in infusion forms as an analgesic, antiasthmatic, digestive and diuretic. AIM OF THE STUDY:The...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.08.006

    authors: Martins JL,Rodrigues OR,da Silva DM,Galdino PM,de Paula JR,Romão W,da Costa HB,Vaz BG,Ghedini PC,Costa EA

    更新日期:2014-09-29 00:00:00

  • Ethyl acetate fraction from Nymphaea hybrida Peck modulates inflammatory responses in LPS-stimulated RAW 264.7 cells and acute inflammation murine models.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Nymphaea hybrida Peck is used as a traditional medicinal herb for treating pain and inflammatory diseases, and known for its ornamental value and as a hot drink. However, the effects of N. hybrida polar fractions on lipopolysaccharide (LPS)-induced in vitro inflammation model and acute in...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113698

    authors: Zhang Z,Jiang S,Tian H,Zeng Y,He K,Lin L,Yu F

    更新日期:2021-04-06 00:00:00

  • Traditional antileukodermic herbal remedies in the Mediterranean area.

    abstract::More than 100 antileukodermic recipes, involving about 80 plant species used in Italy through the centuries, were collected from Renaissance texts, folk medicine and contemporary herbal usage. The possible efficacy of the recorded plants in stimulating physiological skin pigmentation is discussed in the light of prese...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(89)90091-3

    authors: Capitanio M,Cappelletti EM,Filippini R

    更新日期:1989-11-01 00:00:00

  • The pharmacy of the Benedictine monks: the use of medicinal plants in Northeast Brazil during the nineteenth century (1823-1829).

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The health of nineteenth century Brazilians is only alluded to in historical documents, and researchers still have much to discover. AIM OF THE STUDY:This study aims to show the medicinal plants used in the 19th century in Brazil. MATERIALS AND METHODS:To this end, information was obtai...

    journal_title:Journal of ethnopharmacology

    pub_type: 历史文章,杂志文章

    doi:10.1016/j.jep.2011.11.014

    authors: Medeiros MF,de Albuquerque UP

    更新日期:2012-01-06 00:00:00

  • Ethnopharmacological survey on medicinal plants used in herbal drinks among the traditional communities of Pakistan.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:There is very limited information regarding medicinal plants used by traditional healers in Pakistan, for treating wide-ranging diseases. Current study provides significant ethnopharmacological information, both qualitative and quantitative on medical plants in Pakistan and the pharmacolo...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2016.02.039

    authors: Ahmad M,Khan MP,Mukhtar A,Zafar M,Sultana S,Jahan S

    更新日期:2016-05-26 00:00:00

  • Evaluation of French Guiana traditional antimalarial remedies.

    abstract::In order to evaluate the antimalarial potential of traditional remedies used in French Guiana, 35 remedies were prepared in their traditional form and screened for blood schizonticidal activity in vitro on Plasmodium falciparum chloroquine re4sistant strain (W2). Some of these extracts were screened in vivo against Pl...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2004.12.020

    authors: Bertani S,Bourdy G,Landau I,Robinson JC,Esterre P,Deharo E

    更新日期:2005-04-08 00:00:00

  • Anti-inflammatory and analgesic properties of water-ethanolic extract from Pothomorphe umbellata (Piperaceae) aerial parts.

    abstract::Anti-inflammatory and analgesic activities as well as the median lethal dose (LD50) of water-ethanolic extract (PHE) of the aerial parts of Pothomorphe umbellata were evaluated in animal models. The ED(50) (oral) for the inhibition of carrageenan-induced rat paw edema assay was determined to be 550 mg/kg, while the LD...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2005.02.023

    authors: Perazzo FF,Souza GH,Lopes W,Cardoso LG,Carvalho JC,Nanayakkara NP,Bastos JK

    更新日期:2005-06-03 00:00:00

  • Antibacterial activity of Brazilian propolis and fractions against oral anaerobic bacteria.

    abstract::Propolis collected from a cerrado area in Minas Gerais State, Brazil, was subjected to chromatography on silica gel column and to partition between immiscible solvents. Propolis aqueous-ethanolic extract and fractions obtained were tested for inhibitory activity against periodontitis-causing bacteria. All of the assay...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(02)00003-x

    authors: Santos FA,Bastos EM,Uzeda M,Carvalho MA,Farias LM,Moreira ES,Braga FC

    更新日期:2002-04-01 00:00:00

  • Xiaoxuming decoction for acute ischemic stroke: a systematic review and meta-analysis.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Xiaoxuming decoction (XXMD) is a well-known traditional Chinese herbal prescription in treatment of patients with stroke. The objective of this study is to assess the efficacy and safety of XXMD for acute ischemic stroke. MATERIALS AND METHODS:A systematic literature search was conducted...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jep.2013.04.002

    authors: Fu DL,Lu L,Zhu W,Li JH,Li HQ,Liu AJ,Xie C,Zheng GQ

    更新日期:2013-06-21 00:00:00

  • The anti-cancer activity of Antrodia camphorata against human ovarian carcinoma (SKOV-3) cells via modulation of HER-2/neu signaling pathway.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Antrodia camphorata (AC) is well known in Taiwan as a traditional Chinese medicinal fungus. However, the anticancer activity of AC against human HER-2/neu-overexpressing ovarian cancers is poorly understood. MATERIALS AND METHODS:The aim of this study is to investigate whether a submerge...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2013.04.023

    authors: Yang HL,Lin KY,Juan YC,Kumar KJ,Way TD,Shen PC,Chen SC,Hseu YC

    更新日期:2013-06-21 00:00:00

  • Phytochemical flavones isolated from Scutellaria barbata and antibacterial activity against methicillin-resistant Staphylococcus aureus.

    abstract::A crude extract prepared from Scutellaria barbata D. Don (Lamiaceae) was analyzed in the effort to discover antibacterial compounds against high-level strains of methicillin-resistant Staphylococcus aureus (MRSA). Apigenin and luteolin were isolated from the plant as active constituents against the bacteria. These fla...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(00)00265-8

    authors: Sato Y,Suzaki S,Nishikawa T,Kihara M,Shibata H,Higuti T

    更新日期:2000-10-01 00:00:00

  • Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis.

    abstract:AIM OF THE STUDY:The multiple sclerosis is an immuno-mediated disorder of the Central Nervous System characterized by inflammatory processes and neurodegenerative changes. It has been shown that the endocannabinoid system is altered in this disease and that the exogenous cannabinoids may play a possible role in its the...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2010.11.035

    authors: Buccellato E,Carretta D,Utan A,Cavina C,Speroni E,Grassi G,Candeletti S,Romualdi P

    更新日期:2011-02-16 00:00:00

  • Antihyperglycemic activity of Momordica cymbalaria in alloxan diabetic rats.

    abstract::Aqueous, ethanolic and hexane fractions of Momordica cymbalaria fruits were prepared and given individually at different doses to different batches of rats (both normal and alloxan diabetic rats) after an overnight fast. The blood glucose levels were measured at 0, 1, 3, 5 and 7 h after the treatment. The aqueous extr...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(01)00324-5

    authors: Rao BK,Kesavulu MM,Apparao C

    更新日期:2001-11-01 00:00:00

  • Prevention of hepatic injury by a traditional Chinese formulation, BJ-JN, in mice treated with Bacille-Calmette-Guérin and lipopolysaccharide.

    abstract::The hepatoprotective effects of BJ-JN (a traditional Chinese formulation) were evaluated in Bacille-Calmette-Guérin and lipopolysaccharide (BCG/LPS)-induced immunological liver injury (ILI) in mice. BJ-JN (0.75, 1.5, 3 g/kg) was administered via gavage daily for 10 days. Liver index (liver weight/body weight), serum l...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2006.04.006

    authors: Zou Y,Yang Y,Li J,Li W,Wu Q

    更新日期:2006-10-11 00:00:00