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Phytochemical flavones isolated from Scutellaria barbata and antibacterial activity against methicillin-resistant Staphylococcus aureus.

Abstract：

:A crude extract prepared from Scutellaria barbata D. Don (Lamiaceae) was analyzed in the effort to discover antibacterial compounds against high-level strains of methicillin-resistant Staphylococcus aureus (MRSA). Apigenin and luteolin were isolated from the plant as active constituents against the bacteria. These flavonoid congeners were selectively toxic to S. aureus, including the MRSA and methicillin-sensitive S. aureus strains.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Sato Y,Suzaki S,Nishikawa T,Kihara M,Shibata H,Higuti T

doi

10.1016/s0378-8741(00)00265-8

keywords:

subject

Has Abstract

pub_date

2000-10-01 00:00:00

pages

483-8

issue

3

eissn

0378-8741

issn

1872-7573

pii

S0378874100002658

journal_volume

72

pub_type

杂志文章

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