Central nervous system studies on an ethanol extract of Acorus calamus rhizomes.

Abstract:

:An ethanol extract of Acorus calamus rhizomes was screened for CNS effects using a battery of 20 tests in rats and mice. The extract exhibited a large number of actions similar to alpha-asarone (an active principle of A. calamus) but differed from the latter in several other respects including the responses to electroshock, apomorphine- and isolation-induced aggressive behaviour, amphetamine toxicity in aggregated mice, behavioural despair syndrome in forced swimming, etc. These differences could be due to chemical substances yet to be isolated from the plant extract.

journal_name

J Ethnopharmacol

authors

Vohora SB,Shah SA,Dandiya PC

doi

10.1016/0378-8741(90)90065-2

subject

Has Abstract

pub_date

1990-02-01 00:00:00

pages

53-62

issue

1

eissn

0378-8741

issn

1872-7573

pii

0378-8741(90)90065-2

journal_volume

28

pub_type

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