Isolation and antimicrobial activity of two phenolic compounds from Pulicaria odora L.

Abstract:

:The essential oil of Pulicaria odora, a Moroccan medicinal plant; was analyzed by GC-MS, and subjected to column chromatography on silica gel. Two major constituents were isolated and identified as 2-isopropyl-4-methylphenol (1) and isobutyric acid 2-isopropyl-4-methylphenylester (2), by analysis of spectroscopic data (MS, 1H NMR, 13C NMR, DEPT, COSY, HMQC and HMBC experiments). The isolated compounds are reported for the first time from Pulicaria genus. The essential oil and its major constituents (compounds 1 and 2) were examined for antibacterial and antifungal activity in vitro using the diffusion and dilution methods. Results showed that the essential oil and the 2-isopropyl-4-methylphenol (1) exhibited a very significant antibacterial and antifungal activity, while the isobutyric acid 2-isopropyl-4-methylphenylester (2) was inactive for all tested strains.

journal_name

J Ethnopharmacol

authors

Ezoubeiri A,Gadhi CA,Fdil N,Benharref A,Jana M,Vanhaelen M

doi

10.1016/j.jep.2005.02.015

keywords:

subject

Has Abstract

pub_date

2005-06-03 00:00:00

pages

287-92

issue

2

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(05)00165-0

journal_volume

99

pub_type

杂志文章
  • An ethnopharmacological survey of the traditional medicine utilized in the community of Porvenir, Bajo Paraguá Indian Reservation, Bolivia.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Porvenir is a semi-isolated Indian community in the Bajo Paraguá Indian Reservation in Bolivian Amazon, one of the two communities of people from the Guarasug'we indigenous nation now close to extinction. The aim of our study was the collection of data on the traditional medicine utilized...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2011.12.029

    authors: Hajdu Z,Hohmann J

    更新日期:2012-02-15 00:00:00

  • Jodina rhombifolia leaves lyophilized aqueous extract decreases ethanol intake and preference in adolescent male Wistar rats.

    abstract::The leaves of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) are utilized as anti-alcoholic in Argentine folk medicine. This study was designed to investigate the anti-alcohol properties in adolescent male Wistar rats (postnatal day 29; 83-105 g of weight). We utilized the "self-administration model", which e...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2015.07.046

    authors: Roberto Teves M,Wendel GH,Pelzer LE

    更新日期:2015-11-04 00:00:00

  • Evaluation of the protective potential of Artemisia maritima extract on acetaminophen- and CCl4-induced liver damage.

    abstract::The hepatoprotective activity of the aqueous-methanolic extract of Artemisia maritima was investigated against acetaminophen (paracetamol, 4-hydroxy acetanilide)- and carbon tetrachloride (CCl4)-induced hepatic damage. Acetaminophen produced 100% mortality at the dose of 1 g/kg in mice, while pretreatment of animals w...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(95)01252-9

    authors: Janbaz KH,Gilani AH

    更新日期:1995-06-23 00:00:00

  • Muscarinic-dependent inhibition of gastric emptying and intestinal motility by fractions of Maytenus ilicifolia Mart ex. Reissek.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Maytenus ilicifolia Mart. ex. Reissek (Celastraceae) is widely used in Brazilian folk medicine to treat gastric disturbances. AIM OF THE STUDY:This work intended to characterize the effects of Maytenus ilicifolia on gastrointestinal motility. MATERIALS AND METHODS:Gastric emptying and i...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2009.03.037

    authors: Baggio CH,Freitas CS,Mayer B,Dos Santos AC,Twardowschy A,Potrich FB,Cipriani TR,de Souza LM,Sassaki GL,Iacomini M,Marques MC,Mesia-Vela S

    更新日期:2009-06-25 00:00:00

  • Enhancement of wound healing by topical application of Scorzonera species: determination of the constituents by HPLC with new validated reverse phase method.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Scorzonera species are mainly used against arteriosclerosis, kidney diseases, hypertension, diabetes mellitus and rheumatism, as well as for pain relief and wound healing in Turkish folk medicine. In the current study, aerial parts and roots of Scorzonera cinerea, Scorzonera incisa, Scorz...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2011.07.029

    authors: Küpeli Akkol E,Acıkara OB,Süntar I,Citoğlu GS,Keleş H,Ergene B

    更新日期:2011-09-02 00:00:00

  • Antithrombocytopenic activity of carpaine and alkaloidal extract of Carica papaya Linn. leaves in busulfan induced thrombocytopenic Wistar rats.

    abstract:ETHNOPHARMACOLOGICAL RELAVANCE:The decoction of Carica papaya Linn. leaves is used in folklore medicine in certain parts of Malaysia and Indonesia for the treatment of different types of thrombocytopenia associated with diseases and drugs. There are several scientific studies carried out on humans and animal models to ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2016.01.035

    authors: Zunjar V,Dash RP,Jivrajani M,Trivedi B,Nivsarkar M

    更新日期:2016-04-02 00:00:00

  • Salvia miltiorrhiza causes tonic contraction in rat ileum through Ca²⁺-calmodulin pathway.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Danshen, root of Salvia miltiorrhiza (SM), has been traditionally used in Chinese medicine for the treatment of heart, abdomen, gurgling in the intestines, and relieving fullness. However, the effects of SM on intestine have rarely been done to date. AIM OF THE STUDY:To investigate the c...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2012.05.041

    authors: Tsai CC,Huang SC,Liu JK,Wang HC,Tsai TR,Tsai PJ,Liu CW,Chang LC

    更新日期:2012-08-01 00:00:00

  • Hepatoprotective effects of rubiadin, a major constituent of Rubia cordifolia Linn.

    abstract::The hepatoprotective effects of rubiadin, a major constituent isolated from Rubia cordifolia Linn., were evaluated against carbon tetrachloride (CCl4)-induced hepatic damage in rats. Rubiadin at a dose of 50, 100 and 200 mg/kg was administered orally once daily for 14 days. The substantially elevated serum enzymatic a...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2005.08.073

    authors: Rao GM,Rao CV,Pushpangadan P,Shirwaikar A

    更新日期:2006-02-20 00:00:00

  • Antinociceptive, anti-inflammatory and acute toxicity effects of Zataria multiflora Boiss extracts in mice and rats.

    abstract::Antinociceptive, anti-inflammatory and acute toxicity of the aqueous infusion and ethanolic maceration extracts of the aerial parts of Zataria multiflora Boiss were studied in mice and rats. Antinociceptive activity was done using hot-plate and writhing tests. The effect of the extracts against acute inflammation was ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(00)00238-5

    authors: Hosseinzadeh H,Ramezani M,Salmani G

    更新日期:2000-12-01 00:00:00

  • Protection of mouse brain from paracetamol-induced stress by Centella asiatica methanol extract.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Centella asiatica (CA) is a medicinal herb traditionally used as a brain tonic in Ayurvedic medicine. Various ethnomedical leads revealed the effective use of CA in the treatment of symptoms associated to oxidative stress and inflammation. AIM OF THE STUDY:The aim of this study was to ev...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.03.017

    authors: Viswanathan G,Dan VM,Radhakrishnan N,Nair AS,Rajendran Nair AP,Baby S

    更新日期:2019-05-23 00:00:00

  • Apigenin attenuates TGF-β1-stimulated cardiac fibroblast differentiation and extracellular matrix production by targeting miR-155-5p/c-Ski/Smad pathway.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Apigenin is a natural flavonoid compound present in chamomile (Matricaia chamomilla L.) from the Asteraceae family, which is used in the treatment of cardiovascular diseases by traditional healers, but its effects on differentiation and extracellular matrix (ECM) production of cardiac fib...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113195

    authors: Wang F,Fan K,Zhao Y,Xie ML

    更新日期:2021-01-30 00:00:00

  • Preliminary evaluation: the effects of Aloe ferox Miller and Aloe arborescens Miller on wound healing.

    abstract:AIM OF THE STUDY:Genus Aloe has been traditionally utilized for medicinal purpose for decades. Compared with Aloe vera gel, the qualitative assessment for the therapeutic effects of the other two Aloe species, Aloe ferox Miller and Aloe arborescens Miller, for their topical wound healing was less addressed. Therefore, ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2008.08.008

    authors: Jia Y,Zhao G,Jia J

    更新日期:2008-11-20 00:00:00

  • The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In traditional Chinese medicine, processed aconite root (lateral root of Aconitum carmichaelii Debx.) is used as the principle herb of the Si-Ni decoction (SND) formula due to its cardiotonic effect, while its cardiotoxicity and neurotoxicity caused by diester and monoester diterpenoid al...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2018.09.022

    authors: Zhang M,Peng Y,Wang M,Gao B,Zhao L,Li X

    更新日期:2019-01-10 00:00:00

  • The taste of heat: How humoral qualities act as a cultural filter for chemosensory properties guiding herbal medicine.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Organoleptic properties, and more specifically chemosensory cues, have been shown to guide therapeutic applications of medicinal plants. Humoral qualities, on the other hand, are widely believed to be an abstract concept, mainly applied post hoc to validate therapy. However, the nexus bet...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.01.027

    authors: Geck MS,Cabras S,Casu L,Reyes García AJ,Leonti M

    更新日期:2017-02-23 00:00:00

  • Reduced system exposures of total rhein and baicalin after combinatory oral administration of rhein, baicalin and berberine to beagle dogs and rats.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Rhein (Rh), baicalin (BG) and berberine (Be) are important coexisted constituents of San-Huang-Xie-Xin-Tang, which was widely used in traditional Chinese medicine for the treatment of gastritis, hypertension, gastric bleeding and peptic ulcers, etc. AIM OF THE STUDY:Based on the extensiv...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2012.11.008

    authors: Wang Z,Hu H,Chen F,Lan K,Wang A

    更新日期:2013-01-30 00:00:00

  • In vitro immunomodulating properties of selected Sudanese medicinal plants.

    abstract::Ethanolic extracts of 23 medicinal plants, commonly used in Sudanese folk medicines against infectious diseases, were investigated for their immunomodulating activity using luminol/lucigenin-based chemiluminescence assay. Preliminary screenings on whole blood oxidative burst activity showed inhibitory activities of 14...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2008.03.007

    authors: Koko WS,Mesaik MA,Yousaf S,Galal M,Choudhary MI

    更新日期:2008-06-19 00:00:00

  • Antihyperglycemic, antihyperlipidemic and antioxidant effects of ethanol and aqueous extracts of Cyclocarya paliurus leaves in type 2 diabetic rats.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Cyclocarya paliurus (CP) Batal., the sole species in its genus and native to China, is a herbal tea, which has been traditionally used in the folk medicine for the treatment of diabetes and hyperlipidemia in China. To evaluate the antihyperglycemic, antihyperlipidemic and antioxidant effe...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2013.10.040

    authors: Wang Q,Jiang C,Fang S,Wang J,Ji Y,Shang X,Ni Y,Yin Z,Zhang J

    更新日期:2013-12-12 00:00:00

  • Antibacterial activity and in vitro anti-tumor activity of the extract of the larvae of the housefly (Musca domestica).

    abstract::One of the significant characteristics of traditional Chinese medicine is the use of insects, other terrestrial arthropods and their products as drugs. In the present work, the extract of housefly (Musca domestica) larvae was studied by an agar well diffusion assay and minimum bactericidal concentration (MBC) determin...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2006.11.015

    authors: Hou L,Shi Y,Zhai P,Le G

    更新日期:2007-05-04 00:00:00

  • Cytotoxic ethnic Yao medicine Baizuan, leaves of Schisandra viridis A. C. Smith.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The ethnic Chinese Yao medicine Baizuan, which are the leaves of Schisandra viridis A. C. Smith, is traditionally used, in combination with other herbs, to soften hard lumps and dispel nodes in the treatment of cancer, however, this property has not been well studied with a clear indicati...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2016.09.016

    authors: Hou X,Deng J,Zhang Q,Wang D,Kennedy D,Quinn RJ,Feng Y

    更新日期:2016-12-24 00:00:00

  • Anti-inflammatory and anti-pyretic activities of earthworm extract-Lampito mauritii (Kinberg).

    abstract:AIM OF THE STUDY:Experiments were conducted to understand the therapeutic properties such as anti-inflammatory and anti-pyretic activities of biologically active extract isolated from whole earthworm (Lampito mauritii, Kinberg). MATERIALS AND METHODS:Inflammation in the hind paw of Wistar albino rat, Rattus norvegicus...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2008.10.021

    authors: Balamurugan M,Parthasarathi K,Cooper EL,Ranganathan LS

    更新日期:2009-01-21 00:00:00

  • Bu-Shen-Fang-Chuan formula attenuates cigarette smoke-induced inflammation by modulating the PI3K/Akt-Nrf2 and NF-κB signalling pathways.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Chronic obstructive pulmonary disease (COPD) is a respiratory inflammatory disease. Unlike asthma, COPD is insensitive to glucocorticoid treatment; thus, it is of great importance to find alternative medications, including Chinese medicine, to suppress inflammation. Bu-Shen-Fang-Chuan for...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113095

    authors: Li Q,Wang G,Xiong SH,Cao Y,Liu B,Sun J,Li L,Mohammadtursun N,Yu H,Dong J,Wu J

    更新日期:2020-10-28 00:00:00

  • Investigation of antihypertensive mechanism of garlic in 2K1C hypertensive rat.

    abstract::This study sought to examine the antihypertensive mechanism of garlic in two-kidney-one-clip (2K1C) hypertensive rat. In this study, the effect of garlic on serum and tissue including: aorta, heart, kidney, lung as well as circulatory (serum) ACE activity in 2K1C rats were examined. Four groups of rats were selected: ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(03)00080-1

    authors: Sharifi AM,Darabi R,Akbarloo N

    更新日期:2003-06-01 00:00:00

  • A comprehensive quality evaluation of Fuzi and its processed product through integration of UPLC-QTOF/MS combined MS/MS-based mass spectral molecular networking with multivariate statistical analysis and HPLC-MS/MS.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Aconiti Lateralis Radix Praeparata (the Chinese name is Fuzi, FZ), the lateral or daughter root of Aconitum carmichaelii Debx. (Ranunculaceae), is a controversial traditional Chinese medicine (TCM) that is universally distributed and applied in many countries, such as China, Japan, Korea,...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113455

    authors: Lei H,Zhang Y,Ye J,Cheng T,Liang Y,Zu X,Zhang W

    更新日期:2021-02-10 00:00:00

  • Antinociceptive effect of extract of Emilia sonchifolia in mice.

    abstract:AIM OF THE STUDY:Emilia sonchifolia (L.) DC. (Asteraceae) is a medicinal plant traditionally used in Brazilian folk medicine to treat asthma, fever, cuts, wounds and rheumatism. This study was conducted to establish the antinociceptive properties of hydroethanolic extract from aerial parts of Emilia sonchifolia in mice...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2010.12.028

    authors: Couto VM,Vilela FC,Dias DF,Dos Santos MH,Soncini R,Nascimento CG,Giusti-Paiva A

    更新日期:2011-03-24 00:00:00

  • Gynura procumbens ethanol extract and its fractions inhibit macrophage derived foam cell formation.

    abstract:ETHNOPHARMACOLOGY RELEVANCE:Gynura procumbens (Lour.) Merr. displayed cardio-protective effect that may prevent atherogenesis. The primary underlying pathological process of cardiovascular disease is atherosclerosis. Atherosclerotic lesion composed of macrophages, T cells and other immune cells which incorporated with ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.112410

    authors: Manogaran M,Vuanghao L,Mohamed R

    更新日期:2020-03-01 00:00:00

  • Piscicidal properties of piperovatine from Piper piscatorum (Piperaceae).

    abstract::Extraction of the roots of the Amazonian medicinal plant, Piper piscatorum Trelease and Yuncker, with MeOH and subsequent bioassay guided fractionation using the guppy, Girardina guppii yielded the active amide, N-isobutyl-6-(p-methoxyphenyl) 2E, 4E-hexadieneamide (piperovatine) and a second inactive amide, N-isobutyl...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(97)00154-2

    authors: McFerren MA,Rodriguez E

    更新日期:1998-03-01 00:00:00

  • Anti-melanoma activity of Cynanchi atrati Radix is mediated by regulation of NF-kappa B activity and pro-apoptotic proteins.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Cynanchi atrati Radix has been traditionally prescribed for patients with inflammatory fever or chronic tumoral disorders. Melanoma is one of the most devastating cancer types, in which overexpression of nuclear factor kappa B (NF-κB) enables the cancer to survive without apoptosis. To id...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.02.037

    authors: Son SW,Kim HG,Han JM,Lee JS,Choi MK,Lee JS,Son CG

    更新日期:2014-04-11 00:00:00

  • Chemical composition and antifungal activity of essential oils of seven Moroccan Labiatae against Botrytis cinerea Pers: Fr.

    abstract::Essential oils of seven Moroccan Labiatae were chemically analysed by GC-MS and evaluated for their in vitro antifungal activity against Botrytis cinerea. Among them, Origanum compactum and Thymus glandulosus greatly inhibited the growth of the mycelium. The inhibition of Botrytis cinerea was 100% for both oils at 100...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(03)00275-7

    authors: Bouchra C,Achouri M,Idrissi Hassani LM,Hmamouchi M

    更新日期:2003-11-01 00:00:00

  • Effect of the flavonoid fraction of Lithocarpus polystachyus Rehd. on spontaneously hypertensive and normotensive rats.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Lilhocarpus polystachys Rehd. (Sweet Tea, ST) is a folk herbal medicine that has been traditionally used as a natural remedy for hypertension in China, whose mechanism remains unveiled. Flavonoid fraction is considered as the major active components in ST. This study aimed to provide expe...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2012.06.016

    authors: Hou SZ,Xu SJ,Jiang DX,Chen SX,Wang LL,Huang S,Lai XP

    更新日期:2012-09-28 00:00:00

  • In vivo disposition and metabolism of madecassoside, a major bioactive constituent in Centella asiatica (L.) Urb.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Centella asiatica (L.) Urb. herb is frequently used in traditional Chinese medicine for many indications, such as traumatic injuries, keloid and scar. Madecassoside is the main active ingredient of this herb drug with higher content than other triterpenoid constituents. Understandings of ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2013.09.004

    authors: Leng DD,Han WJ,Rui Y,Dai Y,Xia YF

    更新日期:2013-11-25 00:00:00