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Fasciolicidal efficacy of Albizia anthelmintica and Balanites aegyptiaca compared with albendazole.

Abstract：

:An attempt was made to evaluate the oral doses of 9 g/kg-body weight of Albizzia anthelmintica Brong. Mimoaseae stem bark water extract and 9 g/kg body weight of B. aegyptiaca (L) Del. (Balanitaceae) fruit mesocarp water extract (traditionally used as an anthelmintic in the Sudan) compared with 20 mg/kg body weight (recommended dose) of albendazole against Fasciola gigantica adult worm (12 weeks old) in five groups each of three goats (6 month old). Group (I) uninfected control, group (II) infected untreated control, group (III, IV and V) infected and treated as mentioned above respectively. Based on the percentage reduction in fluke counts from the liver post mortum 2 weeks after treatment, the efficacy of the mentioned therapeutics was 95.5, 93.2 and 97.7%, respectively. The characteristic lesions of liver fasciolosis, egg/gm of faeces (EPG), packed cell volume (PCV), haemoglobin concentration, total red blood cells count (RBC), total white blood cells count (WBC) and oesinophil% were significantly different from control and treated groups (P<0.05).

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Koko WS,Galal M,Khalid HS

doi

10.1016/s0378-8741(00)00172-0

keywords:

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

247-52

issue

1-2

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(00)00172-0

journal_volume

71

pub_type

杂志文章

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