In vitro anti-proliferative and antioxidant studies on Devil's Club Oplopanax horridus.

Abstract:

:Devil's Club, Oplopanax horridus (OH), is a widely used folk medicine in Alaska and British Columbia for treating a variety of ailments including arthritis, fever and diabetes. HPLC profiling shows that numerous compounds are present in the 70% ethanolic extract of OH dry root bark powder. OH extract inhibited K562, HL60, MCF7 and MDA-MB-468 cell growth with the 50% inhibition (IC(50)) estimated at 1/2700, 1/1700, 1/500 and 1/2500 dilutions, respectively. Non-cytotoxic concentrations (

journal_name

J Ethnopharmacol

authors

Tai J,Cheung S,Cheah S,Chan E,Hasman D

doi

10.1016/j.jep.2006.05.018

subject

Has Abstract

pub_date

2006-11-24 00:00:00

pages

228-35

issue

2

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(06)00273-X

journal_volume

108

pub_type

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