Abstract：
:Treatment of alcohol-dependent patients was primarily focused on inpatient settings in the past decades. The efficacy of these treatment programs has been evaluated in several studies and proven to be sufficient. However, with regard to the increasing costs in public healthcare systems, questions about alternative treatment strategies have been raised. Meanwhile, there is growing evidence that outpatient treatment might be comparably effective as inpatient treatment, at least for subgroups of alcohol dependents. On that background, the present study aimed to evaluate the efficacy of a high-structured outpatient treatment program in 103 alcohol-dependent patients. 74 patients (72%) terminated the outpatient treatment regularly. At 6 months' follow-up, 95% patients were successfully located and personally re-interviewed. Analyses revealed that 65 patients (64%) were abstinent at the 6-month follow-up evaluation and 37 patients (36%) were judged to be non-abstinent. Pre-treatment variables which were found to have a negative impact (non-abstinence) on the 6-month outcome after treatment were a higher severity of alcohol dependence measured by a longer duration of alcohol dependence, a higher number of prior treatments and a stronger alcohol craving (measured by the Obsessive Compulsive Drinking Scale). Further patients with a higher degree of psychopathology measured by the Beck Depression Inventory (depression) and State-Trait Anxiety Inventory (anxiety) relapsed more often. In summary, results of this study indicate a favorable outcome of socially stable alcohol-dependent patients and patients with a lower degree of depression, anxiety and craving in an intensive outpatient rehabilitation program.
journal_name
Eur Addict Resjournal_title
European addiction researchauthors
Bottlender M,Soyka Mdoi
10.1159/000085548keywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
132-7issue
3eissn
1022-6877issn
1421-9891pii
EAR2005011003132journal_volume
11pub_type
杂志文章abstract：:Data were collected on 1,074 opiate detoxifications conducted with lofexidine, from 40 drug dependency units in the United Kingdom. 671 patients (62.5%) attempted a detoxification in the community, with the remainder attempting an inpatient detoxification. Patients completing the detoxification started on a mean dose ...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000018962
更新日期：1999-03-01 00:00:00
abstract：AIM:The aim of this study was to evaluate the role of the glutamate receptor subunit-7 (GluR7, GRIK 3) rs6691840 (Ser310Ala, T928G) in the pathogenesis of alcohol dependence (AD). METHODS:DNA was provided from AD patients (n = 209) and healthy control subjects (n = 308) all of Polish descent. The history of alcoholism...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000341714
更新日期：2013-01-01 00:00:00
abstract：:Adult attention deficit/hyperactivity disorder (ADHD) often co-occurs with substance use disorders (SUD) and is associated with early onset and more severe development of SUD and with reduced treatment effectiveness. Screening tools allow for a good recognition of possible ADHD in adults with SUD and should be used ro...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000487767
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:Smoking is a highly prevalent addictive behavior with severe and life-shortening health consequences. This is the first study to evaluate the efficacy of a newly developed imaginal variant of approach bias modification (ABM) (i.e., imaginal retraining) for the reduction of craving for tobacco and actual smok...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000509823
更新日期：2020-01-01 00:00:00
abstract：:The current study examined the independent effects of parents' educational attainment and occupational status on adolescent smoking and mediation of smoking-specific communication and parents' smoking behaviours on this link. Data were collected in a multi-informant, full-family design in two sampling waves separated ...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000321258
更新日期：2011-01-01 00:00:00
abstract：:The associations between maternal smoking and nicotine dependence and patterns of smoking and nicotine dependence in offspring were examined in a large community-based sample of adolescents. Data were derived from baseline and 4-year follow-up assessments of 938 respondents aged 14-17 years at the outset of the Early ...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000070980
更新日期：2003-07-01 00:00:00
abstract：OBJECTIVE:Evaluation of the Addiction Severity Index (ASI) as a screen for identifying sexual and physical assault histories. METHOD:The sensitivity and specificity of the ASI assault items were examined in 146 alcoholic patients with the assault questions of the Composite International Diagnostic Interview posttrauma...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000050740
更新日期：2001-12-01 00:00:00
abstract：:The programme of prescribing amphetamines and opiates to drug users in Stockholm carried out from 1965 to 1967 has frequently been referred to in the European drug policy debate. In this article, originally presented at the Conference on Drug Use and Drug Policy in Amsterdam in September 1996, the programme is describ...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000018951
更新日期：1998-12-01 00:00:00
abstract：:We tested the use of some subscales of the psychiatric symptom checklist SCL-90-R in predicting relapse within a 1-year follow-up period after a combined detoxification- and abstinence-focused day patient psychotherapy program in 20 men and 13 women with alcohol dependence. Scores of the SCL-90-R subscales interperson...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000066131
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND:Quality of life (QOL) of patients in opioid substitution treatment (OST) is increasingly being addressed in research. However, no disease- or treatment-specific instrument is available to assess the QOL of this target population. The purpose of this project was to develop the first QOL instrument for OST pat...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000484239
更新日期：2017-01-01 00:00:00
abstract：INTRODUCTION:Buprenorphine has already been registered in 27 European countries for maintenance therapy in opioid-dependent patients. In our office-based prescription study we applied sublingual buprenorphine, initiating the treatment at the addiction clinic with subsequent treatment at the offices of general practitio...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000077698
更新日期：2004-01-01 00:00:00
abstract：AIMS:To describe and assess trends in the use of hallucinogens and other adjunct drugs over a 5-year period. DESIGN:Repeated-measures cross-sectional survey. SETTING AND PARTICIPANTS:Annual magazine-based survey targeting people who use drugs in dance contexts. MEASUREMENTS:Lifetime use prevalence (ever used); age o...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000095816
更新日期：2007-01-01 00:00:00
abstract：:The primary source for evaluating treatment outcome in alcoholism is usually verbal self-report. Because the validity of self-report is often doubted, more objective markers for treatment outcome are needed. In this study, we compared self-report data from 238 male alcohol-dependent patients participating in a combine...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000018972
更新日期：1999-06-01 00:00:00
abstract：BACKGROUND:It has been determined that cannabis has adverse effects on brain tissue, and that increased S100 calcium binding protein B (S100B) blood levels are markers of neuronal damage. Therefore, the aim of this study was to evaluate the S100B levels in cannabis use disorder. METHOD:Thirty-two patients with cannabi...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000442046
更新日期：2016-01-01 00:00:00
abstract：:γ-Butyrolactone (GBL) is a popular drug of abuse which is easily available over the internet. Following a UK classification change to a class C drug in January 2010, internet supply has become difficult. Some of the effects have resulted in sourcing GBL from industrial solvents. We report a case of a 24-year-old man w...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000324343
更新日期：2011-01-01 00:00:00
abstract：:This study investigates whether antismoking peer pressure and/or nonsmoking peers are protective factors and decrease young adults' likelihood to smoke. An experiment was conducted among 59 daily-smoking young adults aged 16-24 years. The experiment consisted of four conditions. During the session, the confederate and...
journal_title：European addiction research
pub_type： 杂志文章,随机对照试验
doi：10.1159/000330318
更新日期：2011-01-01 00:00:00
abstract：AIMS:The aim of this paper is to illustrate how Switzerland was able to play such a pioneering role in the field of addiction treatment, in creating a drug policy that includes the medical prescription of diacetylmorphine (heroin). The paper will also describe the role of knowledge brokering processes and coalition bui...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000357234
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Personality disorders (PD) are related to negative outcome in substance abuse treatment, and in the general population, personality disorders are related to negative outcome in overall functioning. Little is known about the impact of PD on adjustment following substance abuse treatment. METHODS:A cohort of ...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000173006
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associated with psychotic disorders. We compared the prevalence of use, consumer profiles, and psychosis-inducing potential of NC and SCs in a specific high-risk population. METHODS:This prospective pilot study included 332 patie...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000479554
更新日期：2017-01-01 00:00:00
abstract：AIM:The purpose of this study was to investigate the role of serotonergic genes in the development of alcohol dependence. The manifestation of alcohol withdrawal symptoms related to serotonergic polymorphisms in alcoholics was also examined. METHODS:The role of polymorphisms in the serotonin receptor 1A (5-HT1A), sero...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000173008
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:A pre-post pilot study was conducted to test the feasibility, acceptability, and potential effectiveness of a fully automatized computer-based intervention targeting hazardous drinking and depressiveness in proactively recruited health care patients (HCPs). To address the importance of the sample selection w...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000499040
更新日期：2019-01-01 00:00:00
abstract：AIMS:There is a scarcity of clinical trials on psychological treatments for concurrent borderline personality disorder (BPD) and substance use disorder (SUD). Mentalization-based treatment (MBT) have shown efficacy in several trials on BPD. The aim of the present study was to examine the feasibility and effectiveness o...
journal_title：European addiction research
pub_type： 杂志文章,随机对照试验
doi：10.1159/000485564
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:To assess smoking habit and awareness of smoking as a potential cause of disease among relatives of patients with serious smoking-related disorders. DESIGN AND SETTING:A survey using a face-to-face interview-assisted questionnaire at the Ege University Hospital between October 1998 and March 1999. SUBJECTS:...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000059380
更新日期：2002-06-01 00:00:00
abstract：:Both heroin abuse and early life stress (ELS) affect the immune system and the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, accelerated aging due to mild inflammation has been indicated in these conditions. The present study aims to compare plasma levels of apoptosis markers, inflammatory markers, and stre...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000503880
更新日期：2020-01-01 00:00:00
abstract：:There is a long-recognized association between alcohol consumption and aggressive behavior. This study was designed to examine aggression in a group of socially well-adapted recovered alcoholics (RA). The question addressed was whether the treatment, together with long-term abstinence from alcohol, could reduce aggres...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000097938
更新日期：2007-01-01 00:00:00
abstract：:In the UK, few doctors prescribe diamorphine for the treatment of opiate dependence to a small number of patients. A retrospective case note review of patients receiving diamorphine in 2000 was conducted in the UK to determine how and why these patients came to receive a prescription for diamorphine. Patient eligibili...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000101550
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:In 2003, Denmark lowered its tax on spirits, and in 2004, Sweden increased its traveller import quotas. AIM:The aim of the study was to determine whether these two changes increased self-reported alcohol consumption in southern Sweden, which is located near Denmark. METHOD:Data were collected through telep...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000314358
更新日期：2010-01-01 00:00:00
abstract：AIMS:The issue of leptin as a putative state marker of alcohol use and its role in craving has been raised in the last few years. Recently, a strong GABA-ergic modulation of leptin was postulated. The aim of the pilot study was to examine leptin levels in correlation with the strongly GABA-mimetic active substance clom...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000331017
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND/AIMS:To determine whether there is a dose-response relationship between maternal dose of buprenorphine at delivery and neonatal outcomes. METHODS:This retrospective cohort study of 155 maternal-infant dyads exposed to buprenorphine during pregnancy examines the relationship between maternal dose of buprenor...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000441220
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Tobacco product warning labels are a key health communication medium with plain packaging noted as the next step in the evolution of tobacco packaging. We assessed the self-reported impact of text versus pictorial health warnings and the determinants of support for plain packaging of tobacco products in the ...
journal_title：European addiction research
pub_type： 杂志文章
doi：10.1159/000366019
更新日期：2015-01-01 00:00:00
