Pathways into receiving a prescription for diamorphine (heroin) for the treatment of opiate dependence in the United kingdom.

Abstract:

:In the UK, few doctors prescribe diamorphine for the treatment of opiate dependence to a small number of patients. A retrospective case note review of patients receiving diamorphine in 2000 was conducted in the UK to determine how and why these patients came to receive a prescription for diamorphine. Patient eligibility criteria were examined together with doctors' stated reasons for initiating a diamorphine (heroin) prescription. Two hundred and ten sets of patients' case notes were reviewed at 27 of the 42 (64%) drug clinics in England and Wales where diamorphine was prescribed by the doctor. There appeared to be a general consensus among the few doctors who had prescribed diamorphine that it was a treatment of last resort, for those with long histories of heroin use and injecting, and those who had not responded sufficiently well to previous other treatments. However, there was also a small number of patients initiated on diamorphine without ever having previously received opiate treatments and some because they were experiencing problems injecting methadone. This reflects the UK history of the individual doctor's clinical autonomy in deciding when diamorphine is appropriate and the previous lack of nationally agreed patient eligibility criteria.

journal_name

Eur Addict Res

authors

Metrebian N,Mott J,Carnwath Z,Carnwath T,Stimson GV,Sell L

doi

10.1159/000101550

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

144-7

issue

3

eissn

1022-6877

issn

1421-9891

pii

000101550

journal_volume

13

pub_type

杂志文章
  • Fatal Overdoses of Opioids in Israel 2005-2014.

    abstract:AIMS:To explore previously unreported rates and trends in opioid-related mortality in Israel, 2005-2014. METHODS:Data was obtained from the national database on causes of death. Drug poisoning deaths were divided into opioid-related deaths and deaths related to other drugs according to International Classification of ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000485033

    authors: Feingold D,Goldberger N,Haklai Z,Lev-Ran S

    更新日期:2017-01-01 00:00:00

  • Maternal Buprenorphine Dose at Delivery and Its Relationship to Neonatal Outcomes.

    abstract:BACKGROUND/AIMS:To determine whether there is a dose-response relationship between maternal dose of buprenorphine at delivery and neonatal outcomes. METHODS:This retrospective cohort study of 155 maternal-infant dyads exposed to buprenorphine during pregnancy examines the relationship between maternal dose of buprenor...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000441220

    authors: O'Connor AB,O'Brien L,Alto WA

    更新日期:2016-01-01 00:00:00

  • The use of a symptom checklist (SCL-90-R) as an easy method to estimate the relapse risk after alcoholism detoxification.

    abstract::We tested the use of some subscales of the psychiatric symptom checklist SCL-90-R in predicting relapse within a 1-year follow-up period after a combined detoxification- and abstinence-focused day patient psychotherapy program in 20 men and 13 women with alcohol dependence. Scores of the SCL-90-R subscales interperson...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000066131

    authors: Lucht M,Jahn U,Barnow S,Freyberger HJ

    更新日期:2002-11-01 00:00:00

  • The Early Developmental Stages of Psychopathology Study (EDSP): a methodological update.

    abstract::The objectives of the community-based Early Developmental Stages of Psychopathology (EDSP) Study are described along with a detailed account of the overall design, special design features, sample characteristics and instruments used. The EDSP employed a prospective-longitudinal design to study substance use and other ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000052043

    authors: Lieb R,Isensee B,von Sydow K,Wittchen HU

    更新日期:2000-12-01 00:00:00

  • Increased S100B Levels in Cannabis Use Disorder.

    abstract:BACKGROUND:It has been determined that cannabis has adverse effects on brain tissue, and that increased S100 calcium binding protein B (S100B) blood levels are markers of neuronal damage. Therefore, the aim of this study was to evaluate the S100B levels in cannabis use disorder. METHOD:Thirty-two patients with cannabi...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000442046

    authors: Bayazit H,Cicek E,Selek S,Aksoy N,Karababa IF,Kandemir H,Basmaci Kandemir S

    更新日期:2016-01-01 00:00:00

  • Effect of methadone treatment on incarceration rates among injection drug users.

    abstract:BACKGROUND:Methadone maintenance treatment (MMT) has been shown to dramatically reduce illicit opioid use and criminal activity among injection drug users (IDU). However, questions remain concerning the effect of MMT in reducing rates of incarceration among IDU. We therefore sought to investigate the long-term effect o...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000130418

    authors: Werb D,Kerr T,Marsh D,Li K,Montaner J,Wood E

    更新日期:2008-01-01 00:00:00

  • Simultaneous versus delayed treatment of tobacco dependence in alcohol-dependent outpatients.

    abstract:INTRODUCTION:There is a high prevalence of smoking among heavy drinkers, which is often forgotten even though it has important health consequences. AIM:To evaluate the effects that providing an intensive tobacco cessation treatment simultaneously with alcohol dependence treatment versus delayed treatment (first alcoho...

    journal_title:European addiction research

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000321256

    authors: Nieva G,Ortega LL,Mondon S,Ballbè M,Gual A

    更新日期:2011-01-01 00:00:00

  • Association between leptin levels and doses of clomethiazole during alcohol withdrawal: a pilot study.

    abstract:AIMS:The issue of leptin as a putative state marker of alcohol use and its role in craving has been raised in the last few years. Recently, a strong GABA-ergic modulation of leptin was postulated. The aim of the pilot study was to examine leptin levels in correlation with the strongly GABA-mimetic active substance clom...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000331017

    authors: Dammann G,Walter M,Gremaud-Heitz D,Wolfersdorf M,Hartmann S,Wurst FM

    更新日期:2012-01-01 00:00:00

  • Neuro-Immuno-Endocrine Interactions in Early Life Stress and Heroin Withdrawal Timeline.

    abstract::Both heroin abuse and early life stress (ELS) affect the immune system and the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, accelerated aging due to mild inflammation has been indicated in these conditions. The present study aims to compare plasma levels of apoptosis markers, inflammatory markers, and stre...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000503880

    authors: Moeini M,Esmaeil N,Mokhtari HR,Eskandari N,Banafshe HR

    更新日期:2020-01-01 00:00:00

  • Smoking habit among the relatives of patients with serious smoking-related disorders.

    abstract:OBJECTIVE:To assess smoking habit and awareness of smoking as a potential cause of disease among relatives of patients with serious smoking-related disorders. DESIGN AND SETTING:A survey using a face-to-face interview-assisted questionnaire at the Ege University Hospital between October 1998 and March 1999. SUBJECTS:...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000059380

    authors: Goksel T,Ozol D,Bayindir U,Guzelant A

    更新日期:2002-06-01 00:00:00

  • Alcohol use and hazardous drinking among medical specialists.

    abstract:BACKGROUND:Alcohol use among medical specialists remains a delicate topic. However, the number of prevalence studies remains very limited in Western European countries. AIMS:To explore alcohol use and hazardous drinking among male and female medical specialists. METHODS:All medical specialists in Belgium--a typical W...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000341993

    authors: Joos L,Glazemakers I,Dom G

    更新日期:2013-01-01 00:00:00

  • Problematic Smartphone Use, Screen Time and Chronotype Correlations in University Students.

    abstract:BACKGROUND:Besides numerous advantages and commodities offered by smartphones, there are obvious unhealthy effects. The global trend of an increase in the frequency of usage of smartphones, that is, prolonged screen time, is closely related to problematic smartphone use. The aim of our study was to measure the level of...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000506738

    authors: Randjelovic P,Stojiljkovic N,Radulovic N,Stojanovic N,Ilic I

    更新日期:2021-01-01 00:00:00

  • Sensitivity of the Addiction Severity Index physical and sexual assault items: preliminary findings on gender differences.

    abstract:OBJECTIVE:Evaluation of the Addiction Severity Index (ASI) as a screen for identifying sexual and physical assault histories. METHOD:The sensitivity and specificity of the ASI assault items were examined in 146 alcoholic patients with the assault questions of the Composite International Diagnostic Interview posttrauma...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000050740

    authors: Langeland W,van den Brink W,Draijer N,Hartgers C

    更新日期:2001-12-01 00:00:00

  • Anabolic androgenic steroids in the general population: user characteristics and associations with substance use.

    abstract:AIMS:To analyse correlates of anabolic androgenic steroids (AAS) use in the general male population. DESIGN:A national household survey. PARTICIPANTS:Individuals aged 15-64 years in Sweden. MEASUREMENTS:AAS use and potential correlates of AAS use, including demographic data, financial situation, physical training, a...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000333037

    authors: Hakansson A,Mickelsson K,Wallin C,Berglund M

    更新日期:2012-01-01 00:00:00

  • Maternal smoking and smoking in adolescents: a prospective community study of adolescents and their mothers.

    abstract::The associations between maternal smoking and nicotine dependence and patterns of smoking and nicotine dependence in offspring were examined in a large community-based sample of adolescents. Data were derived from baseline and 4-year follow-up assessments of 938 respondents aged 14-17 years at the outset of the Early ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000070980

    authors: Lieb R,Schreier A,Pfister H,Wittchen HU

    更新日期:2003-07-01 00:00:00

  • The relation of a family history of alcoholism, obstetric complications and family environment to behavioral problems among 154 adolescents in Germany: results from the children of alcoholics study in Pomerania.

    abstract:BACKGROUND:Behavioral problems in adolescence have been shown to be associated with the presence of a positive family history of alcoholism (FH+), obstetric complications (OCs), and negative parenting practices. METHOD:This study tested the relation of these factors to aggression/delinquency and attention problems in ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000073721

    authors: Barnow S,Lucht M,Hamm A,John U,Freyberger HJ

    更新日期:2004-01-01 00:00:00

  • Clinical manifestation of alcohol withdrawal symptoms related to genetic polymorphisms of two serotonin receptors and serotonin transporter.

    abstract:AIM:The purpose of this study was to investigate the role of serotonergic genes in the development of alcohol dependence. The manifestation of alcohol withdrawal symptoms related to serotonergic polymorphisms in alcoholics was also examined. METHODS:The role of polymorphisms in the serotonin receptor 1A (5-HT1A), sero...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000173008

    authors: Lee YS,Choi SW,Han DH,Kim DJ,Joe KH

    更新日期:2009-01-01 00:00:00

  • Investigating risk factors for Internet gaming disorder: a comparison of patients with addictive gaming, pathological gamblers and healthy controls regarding the big five personality traits.

    abstract::Engaging in online games has become increasingly important as a part of leisure activity in adolescents and adults. While the majority of people use these games in a healthy way, epidemiological studies show that some develop excessive use and symptoms that are related to those of substance-related addictions. Despite...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000355832

    authors: Müller KW,Beutel ME,Egloff B,Wölfling K

    更新日期:2014-01-01 00:00:00

  • Buprenorphine maintenance: office-based treatment with addiction clinic support.

    abstract:INTRODUCTION:Buprenorphine has already been registered in 27 European countries for maintenance therapy in opioid-dependent patients. In our office-based prescription study we applied sublingual buprenorphine, initiating the treatment at the addiction clinic with subsequent treatment at the offices of general practitio...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000077698

    authors: Ortner R,Jagsch R,Schindler SD,Primorac A,Fischer G,General Practitioner Addiction Team.

    更新日期:2004-01-01 00:00:00

  • Influence of personality disorder features on social functioning in substance-abusing women five years after compulsive residential treatment.

    abstract:BACKGROUND:Personality disorders (PD) are related to negative outcome in substance abuse treatment, and in the general population, personality disorders are related to negative outcome in overall functioning. Little is known about the impact of PD on adjustment following substance abuse treatment. METHODS:A cohort of ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000173006

    authors: Jansson I,Hesse M,Fridell M

    更新日期:2009-01-01 00:00:00

  • Socioeconomic differences in alcohol-specific parenting practices and adolescents' drinking patterns.

    abstract::The aim of this study was to investigate to what extent alcohol-specific parenting practices relate to adolescents' alcohol use, binge drinking, and alcohol-related problems, and whether these associations are moderated by socioeconomic status (SES), i.e. parents' education level and family income. The present data we...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000110408

    authors: Spijkerman R,van den Eijnden RJ,Huiberts A

    更新日期:2008-01-01 00:00:00

  • Cannabis use patterns and their association with DSM-IV cannabis dependence and gender.

    abstract:AIMS:To investigate the gender differences in the patterns of cannabis use (CU), namely frequency, times of day, social context and methods and in their association with DSM-IV cannabis dependence. METHODS:A sample of 3,904 students from German universities was recruited via an internet survey. Logistic regressions an...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000333338

    authors: Noack R,Höfler M,Lueken U

    更新日期:2011-01-01 00:00:00

  • Association between early onset of cigarette, alcohol and cannabis use and later drug use patterns: an analysis of a survey in European metropolises.

    abstract:OBJECTIVES:The study presents data about age of onset of alcohol, cigarette and cannabis use and investigates the association between age of onset and later drug use patterns. METHODS:Using a sample from a cross-sectional multi-site study, personal interviews were conducted with 3,503 individuals aged 12-49 years. Las...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000083038

    authors: Baumeister SE,Tossmann P

    更新日期:2005-01-01 00:00:00

  • Is the use of ecstasy and hallucinogens increasing? Results from a community study.

    abstract:UNLABELLED:This report presents findings of a community survey of 3,021 adolescents and young adults aged 14-24 years in Munich, Germany, carried out to determine the prevalence of use and abuse of and dependence on ecstasy, amphetamines and hallucinogens. The response rate was 71%. RESULTS:(1) In 1995, 4% of the male...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000018925

    authors: Schuster P,Lieb R,Lamertz C,Wittchen HU

    更新日期:1998-03-01 00:00:00

  • Can heroin-dependent individuals benefit from a methadone maintenance treatment program before they drop out against medical advice? A 12-month follow-up study.

    abstract:AIM:Little is known about whether heroin-dependent individuals receiving methadone maintenance treatment (MMT) who were discharged involuntarily and against medical advice (DAMA) get benefits before they left. The aims of this 12-month follow-up study were to examine whether the effects of MMT on depressive symptoms, h...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000342309

    authors: Wang PW,Wu HC,Lin HC,Yen CN,Yeh YC,Chung KS,Chang HC,Yen CF

    更新日期:2013-01-01 00:00:00

  • Feasibility and Acceptability of an Intervention Providing Computer-Generated Tailored Feedback to Target Alcohol Consumption and Depressive Symptoms in Proactively Recruited Health Care Patients and Reactively Recruited Media Volunteers: Results of a Pil

    abstract:BACKGROUND:A pre-post pilot study was conducted to test the feasibility, acceptability, and potential effectiveness of a fully automatized computer-based intervention targeting hazardous drinking and depressiveness in proactively recruited health care patients (HCPs). To address the importance of the sample selection w...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000499040

    authors: Krause K,Guertler D,Moehring A,Batra A,Eck S,Rumpf HJ,Bischof G,Lucht M,Freyer-Adam J,Ulbricht S,John U,Meyer C

    更新日期:2019-01-01 00:00:00

  • Treatment outcome in alcoholism - a comparison of self-report and the biological markers carbohydrate-deficient transferrin and gamma-glutamyl transferase.

    abstract::The primary source for evaluating treatment outcome in alcoholism is usually verbal self-report. Because the validity of self-report is often doubted, more objective markers for treatment outcome are needed. In this study, we compared self-report data from 238 male alcohol-dependent patients participating in a combine...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000018972

    authors: Mundle G,Ackermann K,Günthner A,Munkes J,Mann K

    更新日期:1999-06-01 00:00:00

  • A predictive microsimulation model to estimate the clinical relevance of reducing alcohol consumption in alcohol dependence.

    abstract:BACKGROUND:Alcohol consumption is one of the most important factors for disease and disability in Europe. In clinical trials, nalmefene has resulted in a significant reduction in the number of heavy-drinking days (HDDs) per month and total alcohol consumption (TAC) among alcohol-dependent patients versus placebo. METH...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000362408

    authors: François C,Laramée P,Rahhali N,Chalem Y,Aballéa S,Millier A,Bineau S,Toumi M,Rehm J

    更新日期:2014-01-01 00:00:00

  • Quality of life in patients receiving opioid maintenance therapy. A comparative study of slow-release morphine versus methadone treatment.

    abstract:BACKGROUND/AIMS:In recent years, quality of life (QoL) assessments have proved useful for evaluating and comparing drug treatment programs. To compare QoL of patients maintained on methadone versus slow-release morphine, a prospective, randomized, double-blind, double-dummy, cross-over study was conducted. METHODS:Ove...

    journal_title:European addiction research

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000113724

    authors: Winklbaur B,Jagsch R,Ebner N,Thau K,Fischer G

    更新日期:2008-01-01 00:00:00

  • Effects of parents' education and occupation on adolescent smoking and the mediating role of smoking-specific parenting and parent smoking.

    abstract::The current study examined the independent effects of parents' educational attainment and occupational status on adolescent smoking and mediation of smoking-specific communication and parents' smoking behaviours on this link. Data were collected in a multi-informant, full-family design in two sampling waves separated ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000321258

    authors: Ringlever L,Otten R,de Leeuw RN,Engels RC

    更新日期:2011-01-01 00:00:00