Evolving concepts regarding transient ischemic attacks.

abstract：PURPOSE OF REVIEW:Apolipoprotein C-III (apoC-III) is known to inhibit lipoprotein lipase (LPL) and function as an important regulator of triglyceride metabolism. In addition, apoC-III has also more recently been identified as an important risk factor for cardiovascular disease. This review summarizes the mechanisms by ...

journal_title：Current atherosclerosis reports

authors： Taskinen MR,Packard CJ,Borén J

更新日期：2019-05-20 00:00:00

abstract：:Acute coronary syndromes (ACS), such as unstable angina, acute myocardial infarction, and sudden cardiac death, are commonly associated with the presence of vulnerable plaques in coronary arteries. Rupture or erosion of vulnerable plaques results in the formation of luminal thrombi due to the physical contact between ...

journal_title：Current atherosclerosis reports

authors： Didangelos A,Simper D,Monaco C,Mayr M

更新日期：2009-05-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we describe the mechanism behind coronary artery calcification formation and detection, as well as its implication in cardiovascular disease (CVD) risk stratification, intervention, and prognosis in asymptomatic individuals. RECENT FINDINGS:Multiple cohort and population studies have ...

journal_title：Current atherosclerosis reports

authors： Nguyen HL,Liu J,Del Castillo M,Shah T

更新日期：2019-11-21 00:00:00

abstract：:Inflammation and oxidative processes are key components of atherosclerosis, from fatty streak formation to plaque rupture and thrombosis. Recent basic and clinical studies have identified a number of inflammatory and oxidative processes that appear to play a direct role in atherothrombosis and identify potentially cli...

journal_title：Current atherosclerosis reports

authors： Shishehbor MH,Hazen SL

更新日期：2004-05-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Rheumatoid arthritis (RA) is a chronic, autoimmune disease which may result in a higher risk of cardiovascular (CV) events and stroke. Tissue characterization and risk stratification of patients with rheumatoid arthritis are a challenging problem. Risk stratification of RA patients using tradition...

journal_title：Current atherosclerosis reports

authors： Khanna NN,Jamthikar AD,Gupta D,Piga M,Saba L,Carcassi C,Giannopoulos AA,Nicolaides A,Laird JR,Suri HS,Mavrogeni S,Protogerou AD,Sfikakis P,Kitas GD,Suri JS

更新日期：2019-01-25 00:00:00

abstract：PURPOSE OF REVIEW:Mutations in both nuclear and mitochondrial genes are associated with the development of atherosclerotic lesions in arteries and may provide a partial explanation to the focal nature of lesion distribution in the arterial wall. This review is aimed to discuss the genetic aspects of atherogenesis with ...

journal_title：Current atherosclerosis reports

authors： Orekhov AN,Ivanova EA,Markin AM,Nikiforov NG,Sobenin IA

更新日期：2020-08-09 00:00:00

abstract：:Recent studies confirm and extend previous evidence that lipoprotein (Lp) plays a significant role in atherosclerosis and is one of the top five or six risk factors for cardiovascular disease. In Japanese patients, Lp levels and apo phenotypes are significant predictors for myocardial infarction. Lp levels are signifi...

journal_title：Current atherosclerosis reports

authors： Morrisett JD

更新日期：2000-05-01 00:00:00

abstract：:Biologic therapies involve the utilization of proteins, DNA, antibodies, or other substances derived or synthesized from living tissue for therapeutic effects. There are several biologic therapies in clinical development for the prevention and treatment of atherosclerosis. The most advanced in human trials are apolipo...

journal_title：Current atherosclerosis reports

authors： Davidson MH

更新日期：2004-01-01 00:00:00

abstract：:The original version of this article contains errors in Table 3. "At least 1 project/publication in the year" and "> 1 publication per year" have been switched under the titles of "Clinical Track" and "Physician-Scientist track". ...

journal_title：Current atherosclerosis reports

authors： Saeed A,Dabhadkar K,Virani SS,Jones PH,Ballantyne CM,Nambi V

更新日期：2018-06-19 00:00:00

abstract：:We have developed, tested, and successfully implemented an affordable, evidence-based, comprehensive cardiovascular disease risk-reduction program for use in primary and secondary prevention settings. The program is administered at hospitals, physician practices, cardiac rehabilitation programs, work sites, shopping m...

journal_title：Current atherosclerosis reports

authors： Gordon NF,Salmon RD,Mitchell BS,Faircloth GC,Levinrad LI,Salmon S,Saxon WE,Reid KS

更新日期：2001-11-01 00:00:00

abstract：:Effective prevention of the current annual $400 billion losses from atherosclerosis and cardiovascular disease (CVD) will require preventing primary causes rather than just decreasing signs and symptoms (risk factors) produced by those causes. All CVD risk factors predict a likelihood of CVD, but not all are causes of...

journal_title：Current atherosclerosis reports

authors： Lands B

更新日期：2009-07-01 00:00:00

abstract：:Spontaneous intracerebral hemorrhage (ICH) is a devastating disease with high morbidity and mortality. Acutely, ICH is associated with a sudden surge in intracranial pressure (ICP), as the volume of hematoma increases the pressure in the closed head, leading to non-specific symptoms of ICP: headache, nausea, vomiting,...

journal_title：Current atherosclerosis reports

authors： Ko SB,Choi HA,Lee K

更新日期：2012-08-01 00:00:00

abstract：:We briefly and comprehensively present some of the novel findings in the field of revascularization therapy and management of ST-segment-elevation myocardial infarction (STEMI). We highlight the latest evidence-based advancements in the pharmacological and mechanical treatment of patients who presented with STEMI. Sin...

journal_title：Current atherosclerosis reports

authors： Prodanov P,Widimsky P

更新日期：2014-06-01 00:00:00

abstract：:Few principles in medicine today are as well accepted as the benefits of using statins to reduce cardiovascular risk factors and to prevent cardiovascular disease. The recent withdrawal of a statin (cerivastatin) has lead to a re-examination of all statins, and an attempt to better assess the risk-benefit ratio of thi...

journal_title：Current atherosclerosis reports

authors： Black DM

更新日期：2002-01-01 00:00:00

abstract：:There is a significant prevalence (20%-80% depending on the population and the study) of lipid disorders and other cardiovascular risk factors in people living with HIV infection. This review focuses on HIV and HIV treatment-associated metabolic and cardiovascular concerns, including dyslipidemias, lipodystrophy syndr...

journal_title：Current atherosclerosis reports

authors： Troll JG

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The review aims to describe the differences between men and women in those factors that can influence a worse prognosis in women after an acute cardiovascular event. RECENT FINDINGS:Women adequately treated with current evidence-based medications for acute myocardial infarction and for conventional c...

journal_title：Current atherosclerosis reports

authors： Manfrini O,Cenko E,Bugiardini R

更新日期：2020-09-03 00:00:00

abstract：:The ability for statins to reduce major cardiovascular events and mortality has lead to this drug class being the most commonly prescribed in the world. In particular, the benefit of these drugs in type 2 diabetes (T2D) is well established. In February 2012, the Food and Drug Administration released changes to statin ...

journal_title：Current atherosclerosis reports

authors： Axsom K,Berger JS,Schwartzbard AZ

更新日期：2013-02-01 00:00:00

abstract：:Despite the recent decline in mortality from coronary heart disease (CHD), this disease remains the leading killer of US adults of all ages. CHD in young adults is not as well characterized as CHD in older individuals because it occurs less frequently, but this disease can have devastating consequences for young patie...

journal_title：Current atherosclerosis reports

authors： Rubin JB,Borden WB

更新日期：2012-04-01 00:00:00

abstract：:Dyslipidemia is central to the process of atherosclerosis. Modification of the lipid profile by diet, exercise, or pharmacologic therapy has been demonstrated to reduce the risk from atherosclerosis in clinical studies in primary and secondary prevention. Nicotinic acid has been in clinical use for over 50 years. The ...

journal_title：Current atherosclerosis reports

authors： Farmer JA

更新日期：2009-03-01 00:00:00

abstract：:With each passing year, the evidence linking an increased risk for coronary heart disease (CHD) death with a chronic dietary deficiency in long-chain omega-3 (n-3) fatty acids (FAs) grows stronger. Recently, a federally mandated evidence-based review in the United States concluded that n-3 FAs, especially eicosapentae...

journal_title：Current atherosclerosis reports

authors： Harris WS

更新日期：2004-11-01 00:00:00

abstract：:There has been increasing interest in the health benefits of supplemental and/or dietary omega-3 polyunsaturated fatty acids (PUFAs), particularly in their role in disease prevention. This interest escalated once their effects on cardiovascular health were observed from numerous observational studies in populations wh...

journal_title：Current atherosclerosis reports

authors： Fares H,Lavie CJ,DiNicolantonio JJ,O'Keefe JH,Milani RV

更新日期：2014-02-01 00:00:00

abstract：:Lipid-lowering medications, particularly statins, have been a popular target for pharmacogenetic studies. A handful of genes have shown promise for predicting response to therapy from the perspective of lipid lowering, as well as myopathy. A number of genes have been implicated and have biological plausibility based o...

journal_title：Current atherosclerosis reports

authors： Alfonsi JE,Hegele RA,Gryn SE

更新日期：2016-05-01 00:00:00

abstract：:The matrix metalloproteinase (MMP) family of enzymes is involved in arterial wall extracellular matrix degradation and remodeling. The latter activities have been implicated in a number of normal and pathologic processes, such as atherosclerotic lesion formation and progression, plaque destabilization and rupture, but...

journal_title：Current atherosclerosis reports

authors： Ketelhuth DF,Bäck M

更新日期：2011-04-01 00:00:00

abstract：:Lipodystrophies are a group of heterogeneous diseases characterized by the loss of adipose tissue and by abnormalities of carbohydrate and lipid metabolism, including insulin resistance, diabetes, and hyperlipidemia. In this review, we describe several mouse models that recapitulate various aspects of the lipodystroph...

journal_title：Current atherosclerosis reports

authors： Reue K,Péterfy M

更新日期：2000-09-01 00:00:00

abstract：:Plant-derived alpha-linolenic acid has been studied in a limited number of investigations. So far, some epidemiologic and a few mechanistic studies suggest a potential of protection from cardiovascular disease, but this potential remains to be proven in intervention studies. In contrast, eicosapentaenoic acid (EPA) an...

journal_title：Current atherosclerosis reports

authors： von Schacky C

更新日期：2003-03-01 00:00:00

abstract：:High-density lipoprotein cholesterol (HDL-C) levels are inversely related to risk of atherosclerotic cardiovascular disease (ASCVD). However, the simplistic assumption that HDL-C levels directly and causally impact atherogenesis has been challenged in recent years. The purpose of this article is to review the current ...

journal_title：Current atherosclerosis reports

authors： Brunham LR

更新日期：2016-12-01 00:00:00

abstract：:Pharmacotherapies with agents that inhibit platelet function have proven to be effective in the treatment of acute coronary syndromes, and in the prevention of complications during and after percutaneous coronary intervention. Because of multiple synergetic pathways of platelet activation and their close interplay wit...

journal_title：Current atherosclerosis reports

authors： Kalra K,Franzese CJ,Gesheff MG,Lev EI,Pandya S,Bliden KP,Tantry US,Gurbel PA

更新日期：2013-12-01 00:00:00

abstract：:Preliminary evidence demonstrating that adding 0.5 mg of colchicine per day to statin and antiplatelet therapy reduced the risk of acute coronary events in patients with stable coronary artery disease has raised the hope that it may prove effective for the long-term secondary prevention of cardiovascular disease. The ...

journal_title：Current atherosclerosis reports

authors： Nidorf SM,Eikelboom JW,Thompson PL

更新日期：2014-03-01 00:00:00

abstract：:Lipoprotein apheresis is an extracorporeal therapy whereby apo B-containing lipoproteins (LDL, vLDL, and Lp(a)) are selectively removed from the plasma of a patient. It is a variation of plasma exchange, which non-selectively removes all plasma proteins. Lipoprotein apheresis is most commonly used to treat patients wi...

journal_title：Current atherosclerosis reports

authors： Bhoj VG,Sachais BS

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Coronary artery disease (CAD) is a major cause of morbidity and mortality globally and poses a threat to both men and women across their lifespans. There is accumulating evidence to support that CAD may present differently in women and men, ranging from the clinical presentation, diagnosis, and manage...

journal_title：Current atherosclerosis reports

authors： Madan N,Gajo E,Sanghani RM,Volgman AS

更新日期：2020-06-23 00:00:00