Abstract:
:Lipodystrophies are a group of heterogeneous diseases characterized by the loss of adipose tissue and by abnormalities of carbohydrate and lipid metabolism, including insulin resistance, diabetes, and hyperlipidemia. In this review, we describe several mouse models that recapitulate various aspects of the lipodystrophy syndrome, offering insights into the etiology of this condition and potential therapeutic approaches. Studies on these mice suggest that adipose is the primary tissue affected in lipodystrophy, and that secondary leptin deficiency may be responsible for the associated insulin resistance.
journal_name
Curr Atheroscler Repjournal_title
Current atherosclerosis reportsauthors
Reue K,Péterfy Mdoi
10.1007/s11883-000-0077-1keywords:
subject
Has Abstractpub_date
2000-09-01 00:00:00pages
390-6issue
5eissn
1523-3804issn
1534-6242journal_volume
2pub_type
杂志文章,评审abstract::Augmentative and alternative communication (AAC) strategies traditionally have been designed for individuals for whom oral speech is not a viable option. Common clinical practice has expanded AAC use to a tool for cognitive retraining or remediation. Although technologic developments offer the potential for vastly imp...
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pub_type: 杂志文章,评审
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abstract:PURPOSE OF REVIEW:Lipoprotein apheresis is a very efficient but time-consuming and expensive method of lowering levels of low-density lipoprotein cholesterol, lipoprotein(a)) and other apoB containing lipoproteins, including triglyceride-rich lipoproteins. First introduced almost 45 years ago, it has long been a therap...
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pub_type: 杂志文章,评审
doi:10.1007/s11883-019-0787-5
更新日期:2019-05-01 00:00:00
abstract::Atherosclerosis is a complex disease associated with aberrant lipoprotein metabolism and leukocyte infiltration into arterial tissue that leads to cardiovascular diseases. Statins have emerged as among the most effective means of reducing the risk of cardiovascular disease in both primary and secondary prevention sett...
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pub_type: 杂志文章,评审
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更新日期:2013-01-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-014-0408-2
更新日期:2014-05-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-016-0607-0
更新日期:2016-09-01 00:00:00
abstract:PURPOSE OF REVIEW:This review summarizes the pathophysiology of calcific aortic valve stenosis (CAVS) and surveys relevant clinical data and basic research that explain how CAVS arises. RECENT FINDINGS:Lipoprotein(a) [Lp(a)], lipoprotein-associated phospholipase A2 (Lp-PLA2), oxidized phospholipids (OxPL), autotaxin, ...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-020-0821-7
更新日期:2020-01-07 00:00:00
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journal_title:Current atherosclerosis reports
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更新日期:2004-11-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-020-00892-2
更新日期:2020-10-16 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2015-12-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2009-03-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2000-01-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-004-0104-8
更新日期:2004-03-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-011-0201-4
更新日期:2011-12-01 00:00:00
abstract::Atherosclerosis remains the major cause of morbidity and mortality in Western countries. Atherothrombotic complications, including vascular occlusions and severe narrowing of nutrient blood vessels in the cerebral, coronary, or peripheral circulation, usually require invasive revascularization strategies. As molecular...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-003-0022-1
更新日期:2003-05-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章
doi:10.1007/s11883-010-0114-7
更新日期:2010-07-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-001-0077-9
更新日期:2001-09-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2005-09-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-017-0638-1
更新日期:2017-01-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-000-0065-5
更新日期:2000-07-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2016-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Coronary artery no-reflow phenomenon is an incidental outcome of percutaneous coronary intervention in patients presenting with acute myocardial infarction. Despite advances in pharmacologic and non-pharmacologic therapies, coronary no-reflow phenomenon occurs more commonly than desired. It often resu...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章
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更新日期:2018-07-05 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2020-05-26 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2014-04-01 00:00:00
abstract::The original version of this article contains errors in Table 3. "At least 1 project/publication in the year" and "> 1 publication per year" have been switched under the titles of "Clinical Track" and "Physician-Scientist track". ...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章,已发布勘误
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更新日期:2018-06-19 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章
doi:10.1007/s11883-007-0066-8
更新日期:2007-12-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2012-06-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-018-0721-2
更新日期:2018-03-07 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2014-04-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章
doi:10.1007/s11883-019-0767-9
更新日期:2019-02-02 00:00:00
abstract::Due to typesetting mistake, an unknown image was accidentally captured as graphical abstract. This should be removed. ...
journal_title:Current atherosclerosis reports
pub_type: 已发布勘误
doi:10.1007/s11883-020-00868-2
更新日期:2020-07-07 00:00:00