Abstract：
:Corynebacterium glutamicum, a Gram-positive soil bacterium belonging to the mycolic acids-containing actinomycetes, is able to use the lignin degradation products ferulate, vanillate, and protocatechuate as sole carbon sources. The gene cluster responsible for vanillate catabolism was identified and characterized. The vanAB genes encoding vanillate demethylase are organized in an operon together with the vanK gene, coding for a transport system most likely responsible for protocatechuate uptake. While gene disruption mutagenesis revealed that vanillate demethylase is indispensable for ferulate and vanillate utilization, a vanK mutation does not lead to a complete growth arrest but to a decreased growth rate on protocatechuate, indicating that one or more additional protocatechuate transporter(s) are present in C. glutamicum.
journal_name
Curr Microbioljournal_title
Current microbiologyauthors
Merkens H,Beckers G,Wirtz A,Burkovski Adoi
10.1007/s00284-005-4531-8keywords:
subject
Has Abstractpub_date
2005-07-01 00:00:00pages
59-65issue
1eissn
0343-8651issn
1432-0991journal_volume
51pub_type
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