Abstract:
:While the role of C2-ceramide in the induction of programmed cell death (PCD) in animal systems has been well documented, little is known of its role in plant cells. Here we show that C2-ceramide induces PCD in Arabidopsis suspension cultures, which is preceded by the generation of a calcium transient and an increase in reactive oxygen species (ROS). Inhibition of the calcium transient prevented cell death, whereas inhibition of ROS had no effect on cell survival. These observations suggest that calcium signalling plays a role in ceramide-induced PCD but is independent of the generation of ROS.
journal_name
Biol Chemjournal_title
Biological chemistryauthors
Townley HE,McDonald K,Jenkins GI,Knight MR,Leaver CJdoi
10.1515/BC.2005.020keywords:
subject
Has Abstractpub_date
2005-02-01 00:00:00pages
161-6issue
2eissn
1431-6730issn
1437-4315journal_volume
386pub_type
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