Abstract：
BACKGROUND:It has been suggested that increased hepatic and intramuscular fat is associated with insulin resistance, and that increased pancreatic fat is related to impaired insulin secretion. OBJECTIVE:We postulated that in obese nondiabetic teenagers insulin levels would be directly related to increases in intramuscular and hepatic fat and inversely related to increases in pancreatic fat. MATERIALS AND METHODS:MRI was used to assess the percentage of fat in the liver, muscle and pancreas in 15 healthy Mexican-American girls, 14-17 years old, with body mass indexes (BMIs) ranging from 17.7 kg/m(2) to 46 kg/m(2). RESULTS:Strong correlations were observed between BMI and fat content in the liver, muscle, and pancreas (r(2)s between 0.50 and 0.89; P<0.003). Serum insulin levels were closely associated with fat measures in the muscle and liver (r(2s)=0.63 and 0.29, and P=0.001 and P=0.023, respectively). In contrast to our hypothesis, fat content in the pancreas was also directly related to insulin secretion (r(2)=0.74; P=0.001). SUMMARY:We conclude that in nondiabetic teenagers, obesity is associated with an increased accumulation of fat in the pancreas without impairment of insulin secretion.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Kovanlikaya A,Mittelman SD,Ward A,Geffner ME,Dorey F,Gilsanz Vdoi
10.1007/s00247-005-1413-ykeywords:
subject
Has Abstractpub_date
2005-06-01 00:00:00pages
601-7issue
6eissn
0301-0449issn
1432-1998journal_volume
35pub_type
杂志文章abstract：:Three very low birth weight infants, treated with frusemide for broncho-pulmonary dysplasia are described. They all developed medullary nephrocalcinosis identifiable by real time ultrasound. The sonographic findings of diffuse medullary hyper-echogenicity appears to be specific for nephrocalcinosis. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02389002
更新日期：1988-01-01 00:00:00
abstract：:Ultrasound (US) has been proposed as an alternative first-line imaging modality to diagnose community-acquired pneumonia in children. Lung US has the potential benefits over chest radiography of being radiation free, subject to fewer regulatory requirements, relatively lower cost and with immediate bedside availabilit...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-017-3910-1
更新日期：2017-10-01 00:00:00
abstract：:Castleman's disease is a benign lymphoproliferative disorder characterised by enlarged hyperplastic lymph nodes. It is rare in children and usually presents as localised disease. Subpectoral involvement has not been previously described in multicentric Castleman's disease in children. We present the CT, US and Doppler...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-003-0947-0
更新日期：2003-08-01 00:00:00
abstract：:The Nuss procedure has succeeded in minimizing incisions, blood loss, sternal fracturing, operating room time, recovery time, and length of hospital stay. Knowledge of the pre- and postoperative radiologic considerations is essential in providing appropriate imaging support to the surgeons performing this innovative, ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470100455
更新日期：2001-06-01 00:00:00
abstract：BACKGROUND:Optic pathway gliomas (OPGs) are common pediatric brain tumors that pose significant clinical challenges with regard to predicting which tumors are likely to become symptomatic and require treatment. These tumors can arise sporadically or in the context of the inherited cancer predisposition syndrome neurofi...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-008-1003-x
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:Peripherally inserted central catheter (PICC) is among the most common procedures performed in children in the hospital setting. PICC insertion can be simplified with the use of a sheathed needle as an alternative to the modified Seldinger technique. OBJECTIVE:To retrospectively evaluate PICC placement for ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-016-3629-4
更新日期：2016-09-01 00:00:00
abstract：:This retrospective study documents the incidence and distribution of fractures in 117 children with end-stage liver disease who underwent orthotopic liver transplantation (OLT) over a 6-year period (1987-1993). Both the pre- and post-OLT phases were included. Nineteen children (16.2 %) sustained a total of 69 fracture...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND:The diagnosis of Hirschsprung's disease is usually made in neonates but often considered in older infants and children with constipation: these children may be referred for barium enema. Since it is widely accepted that a normal barium enema does not exclude Hirschsprung's disease, some children, after a nor...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470000298
更新日期：2000-10-01 00:00:00
abstract：:A patient with Down syndrome is presented who had hypospadias, a large low implanted prostatic utricle, and refluxing ejaculatory ducts entering the utricle. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02021709
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:Resistivity index (RI) of the pericallosal artery as is commonly measured during head ultrasound (US) examination in neonates. Some studies have shown that RI measured with gentle compression of the fontanelle provides additional information in cases of neonatal brain anomalies. OBJECTIVE:The purpose of thi...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-019-04347-y
更新日期：2019-05-01 00:00:00
abstract：BACKGROUND:Conventional MRI sequences are often affected in neuropediatric imaging by unavoidable movements. Therefore, children younger than 6 years usually have to be examined under sedation/anesthesia. A new real-time MRI technique with automatic slice advancement allows for motion-robust T2-weighted volume coverage...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-020-04771-5
更新日期：2020-11-01 00:00:00
abstract：:Shaken-baby syndrome (SBS) is a type of child abuse caused by violent shaking of an infant, with or without impact, and characterized by subdural hematomas, retinal hemorrhages, and occult bone fractures. Parenchymal brain lesions in SBS may be missed or underestimated on CT scans, but can be detected at an earlier st...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-003-1025-3
更新日期：2003-12-01 00:00:00
abstract：:Recently, the state of California enacted a law requiring radiologists to record the radiation dose that each patient receives for a CT scan. Failure to do so is penalized by law. This law becomes effective in July 2012. By July 2013, every facility that performs CT scans must become accredited by one of three profess...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-011-2105-4
更新日期：2011-09-01 00:00:00
abstract：:Chylopericardium rarely occurs in pediatric patients, but when it does it is most often a result of lymphatic injury during cardiothoracic surgery. Primary idiopathic chylopericardium is especially rare, with few cases in the pediatric literature. We report a 10-year-old boy who presented with primary idiopathic chylo...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-014-3182-y
更新日期：2015-06-01 00:00:00
abstract：:We present a case of herpes simplex encephalitis in an 8-year-old girl, in whom hyperintensity was detected on diffusion-weighted imaging (DWI) while conventional MRI sequences were normal 1 week after the onset of neurological symptoms. This case is rare in that a child beyond the neonatal period with focal herpes si...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-007-0577-z
更新日期：2007-11-01 00:00:00
abstract：:Deep venous thrombosis (DVT) is being increasingly recognized as a significant issue in children. Despite the low incidence of DVT, the risks of pulmonary embolism and death in children are significant. Post-thrombotic syndrome, a syndrome of chronic venous insufficiency, can have long-term adverse consequences in chi...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-013-2634-0
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Shielding of the gonads is a dose-saving strategy in pediatric radiography and its use is the law in New York and the majority of other states. However, routine use of gonadal shields is controversial because of concerns that important diagnostic information can be obscured. OBJECTIVE:The purpose of this st...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-013-2700-7
更新日期：2013-10-01 00:00:00
abstract：:Eosinophilic cystitis is a rare inflammatory condition of the urinary bladder of unknown aetiology and characterized by eosinophilic infiltration of the bladder wall. We report the unique MR findings of eosinophilic cystitis in an 8-year-old girl who presented with peripheral eosinophilia. MR imaging revealed smooth a...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-007-0511-4
更新日期：2007-08-01 00:00:00
abstract：:Gonadal dysgenesis and coarctation of the aorta were found in four patients to be associated with premature sternal fusion but possible etiologic relationship to shield chest deformity in suggested. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02386775
更新日期：1985-01-01 00:00:00
abstract：:Radiographic differentiation between cystic fibrosis and asthma presenting in teenagers and young adults can be difficult. Many patients with a late presentation of cystic fibrosis display minimal changes on a chest radiograph. However, a large majority (90%) of cystic fibrosis patients with an essentially normal PA c...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02388758
更新日期：1985-01-01 00:00:00
abstract：:beta-Thalassaemia major is a hereditary haemolytic anaemia that is treated with multiple blood transfusions. A major complication of this treatment is iron overload, which leads to cell death and organ dysfunction. Chelation therapy, used for iron elimination, requires effective monitoring of the body burden of iron, ...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-007-0567-1
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:When administered to an immune-compromised patient, BCG (Bacille Calmette-Guérin) can cause disseminated and life-threatening infections. OBJECTIVE:To describe the imaging findings in children with primary immunodeficiency and BCG-related infections. MATERIALS AND METHODS:We reviewed the imaging findings o...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-015-3464-z
更新日期：2016-02-01 00:00:00
abstract：:We report a case of perforation, fistula formation, and small bowel obstruction in a 2-year-old child who had ingested 32 small magnets. Multiple magnets will attract one another through the bowel wall and lead to pressure necrosis with complications. We recommend early surgical intervention before the onset of gastro...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-005-0056-3
更新日期：2006-03-01 00:00:00
abstract：BACKGROUND:Hepatic involvement is frequent in patients with cystic fibrosis (CF), with focal biliary cirrhosis being the pathognomonic hepatic manifestation. In around one-quarter of CF patients, it results in CF-associated liver disease (CFLD). This occurs as a relatively early complication with the majority of patien...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-009-1531-z
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Keutel syndrome is a rare autosomal-recessive condition characterized by abnormal cartilage calcification. Neuroimaging findings associated with this condition have been randomly described in the literature. OBJECTIVE:To systematically evaluate the neuroimaging findings in a series of children with Keutel s...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-013-2768-0
更新日期：2014-01-01 00:00:00
abstract：:Kidney length (KL), renal area and renal parenchymal area were measured on i.v. urograms of 255 children without apparent kidney disease age 0 to 14 years. These parameters were compared with age, body height, body surface area and the distance between the 1st and 4th lumbar vertebral body. In addition, renal parenchy...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF01464310
更新日期：1980-04-01 00:00:00
abstract：BACKGROUND:Fetal MRI at 3 T is associated with increased acoustic noise relative to 1.5 T. OBJECTIVE:The goal of this study is to determine if there is an increased prevalence of congenital hearing loss in neonates who had a 3-T prenatal MR vs. those who had it at 1.5 T. MATERIALS AND METHODS:We retrospectively ident...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-018-4261-2
更新日期：2019-01-01 00:00:00
abstract：:Osteoporosis is a generalised disorder of the skeleton with reduced bone density and abnormal bone architecture. It increases bone fragility and renders the individual susceptible to fractures. Fractures of the vertebrae are common osteoporotic fractures. Vertebral fractures may result in scoliosis or kyphosis and, be...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-018-4279-5
更新日期：2019-03-01 00:00:00
abstract：:Sonographic examination of the adrenal glands of three newborns with congenital adrenal hyperplasia demonstrated a cerebriform pattern. This is introduced as a sonographic feature specific to the disease. This finding in patients with ambiguous genitalia should suggest the diagnosis even if the adrenals are not signif...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02012391
更新日期：1993-01-01 00:00:00
abstract：:Gallbladder volvulus in children is rare. Pre-operative diagnosis is considered difficult because of the nonspecific symptoms and inflammatory blood analysis findings. Sometimes diagnosis is confirmed at laparotomy. Many reports mention that the chief complaints of this disease are sudden and severe abdominal pain. We...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-010-1753-0
更新日期：2011-01-01 00:00:00
