Bone fractures in children undergoing orthotopic liver transplantation.

Abstract:

:This retrospective study documents the incidence and distribution of fractures in 117 children with end-stage liver disease who underwent orthotopic liver transplantation (OLT) over a 6-year period (1987-1993). Both the pre- and post-OLT phases were included. Nineteen children (16.2 %) sustained a total of 69 fractures. Age at time of fracture ranged from 3 months to 9 years 8 months (median 13.5 months). There was no documented trauma in 14/19 cases. Metabolic bone disease, assessed qualitatively on plain radiographs, was present in 17/19 children at the time of fracture. This took the form of rickets (n = 3), osteopenia (n = 12) and osteosclerosis (n = 2). Potential risk factors including pre-existing metabolic bone disease, drugs and immobilization were assessed. The findings emphasise the need for clinical and radiological awareness of the fracture risk, particularly during the peri-transplant period when this risk may be greatest.

journal_name

Pediatr Radiol

journal_title

Pediatric radiology

authors

Hill SA,Kelly DA,John PR

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

S112-7

eissn

0301-0449

issn

1432-1998

journal_volume

25 Suppl 1

pub_type

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