Abstract:
BACKGROUND:The diagnosis of Hirschsprung's disease is usually made in neonates but often considered in older infants and children with constipation: these children may be referred for barium enema. Since it is widely accepted that a normal barium enema does not exclude Hirschsprung's disease, some children, after a normal enema, undergo more invasive procedures such as rectal manometry or biopsy. Our study asked how frequently a diagnosis of Hirschsprung's disease was made by biopsy or manometry in children who had normal barium enema. MATERIALS AND METHODS:We reviewed the medical records and barium enemas of 54 patients older than 28 days with constipation or difficulty passing stool who had a barium enema followed by manometry and/or biopsy. RESULTS:Forty-eight patients had normal enemas: 24 of those patients had biopsies, 16 had manometry, and 8 both manometry and biopsy. Only 1 had manometry suggestive of Hirschsprung's disease, confirmed by biopsy. Six patients had abnormal enemas. Five had biopsy and manometry compatible with Hirschsprung's disease; one had a normal biopsy and manometry study. CONCLUSION:The barium enema is a good initial screening test for Hirschsprung's disease in severely constipated children since it correlates well with manometry and biopsy. The enema is particularly useful in centers without easy access to pediatric gastroenterology services, and a normal enema in this setting allows the continuation of medical therapy with further evaluation only if there is a lack of response. An abnormal enema, however, requires referral to a facility equipped to perform confirmatory manometry or biopsy.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Reid JR,Buonomo C,Moreira C,Kozakevich H,Nurko SJdoi
10.1007/s002470000298keywords:
subject
Has Abstractpub_date
2000-10-01 00:00:00pages
681-4issue
10eissn
0301-0449issn
1432-1998journal_volume
30pub_type
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journal_title:Pediatric radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s002470050754
更新日期:2000-05-01 00:00:00
abstract::Gorham's disease may develop in any region of the skeleton, but shows a predilection for the bones of the shoulders and pelvic girdles. Less frequently, the disease may involve the spine, and it is the proximity to the spinal cord which may worsen the patient's outcome. We report the clinical outcomes of two children ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012113
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journal_title:Pediatric radiology
pub_type: 杂志文章
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更新日期:2004-12-01 00:00:00
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更新日期:2020-02-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
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更新日期:1989-01-01 00:00:00
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更新日期:2005-02-01 00:00:00
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journal_title:Pediatric radiology
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更新日期:2017-02-01 00:00:00
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pub_type: 杂志文章
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journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF00973535
更新日期:1977-09-01 00:00:00
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更新日期:1978-12-04 00:00:00
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更新日期:1985-01-01 00:00:00
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更新日期:1986-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2004-09-01 00:00:00
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更新日期:1995-01-01 00:00:00
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更新日期:2018-12-01 00:00:00
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更新日期:1988-01-01 00:00:00
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更新日期:2005-06-01 00:00:00
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