Abstract：
:Evaluation of prognostic factors of adenocarcinoma of Vater's ampulla is still a matter of debate. The aim of this study was to evaluate retrospectively factors that influence early and long-term outcomes in a 20-year single-institution experience on ampullary carcinoma. A total of 94 consecutive patients with ampullary carcinoma or adenoma with severe dysplasia were managed from 1981 to 2002. Among them, 64 underwent pancreatoduodenectomy, and the remaining 30 submitted to surgical (n = 5) or endoscopic (n = 25) palliative treatment. Demographic, clinical, and pathologic data were collected, and a comparison was made between patients who did or did not undergo resection. Standard statistical analyses were carried out in an attempt to establish a correlation between clinical variables, intraoperative and pathologic factors, and survival in patients with resection. A total of 85 (90.4%) patients had potentially resectable lesions due to the extent of the tumor, but only 64 (68%) underwent curative resection. The surgical morbidity rate was 34.3%. Postoperative mortality was 9.3%, with no deaths among the 38 more recently treated patients. Median survivals were 9 and 54 months for nonresected and resected patients, respectively. The overall 5-year survival was 64.4% for patients undergoing pancreatoduodenectomy. Survival was found to be significantly affected by resection, tumor size, tumor grade, and tumor infiltration. Patients with negative lymph nodes show a trend toward longer survival. In a multivariate analysis, only the depth of tumor infiltration influenced patient survival. Pancreatoduodenectomy is the treatment of choice for ampullary carcinoma and adenomas with high-grade dysplasia, with a good chance of long-term survival. Surgical resection remains the most important factor influencing outcome.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Di Giorgio A,Alfieri S,Rotondi F,Prete F,Di Miceli D,Ridolfini MP,Rosa F,Covino M,Doglietto GBdoi
10.1007/s00268-004-7498-xkeywords:
subject
Has Abstractpub_date
2005-04-01 00:00:00pages
513-8issue
4eissn
0364-2313issn
1432-2323journal_volume
29pub_type
杂志文章abstract：:The effects of pneumoperitoneum on the lower esophageal sphincter (LES) were evaluated during laparoscopic operation for esophageal achalasia. Intraoperative manometry was performed in three patients who underwent laparoscopic cardiomyectomy with Dor's fundoplication and five patients who underwent laparoscopic cholec...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900146
更新日期：1996-10-01 00:00:00
abstract：BACKGROUND:Although mortality after liver resection has declined, posthepatectomy liver failure (PHLF) remains a major cause of operative mortality. To date there is not consensus on a definition for PHLF. However, there have been many efforts to define PHLF causing operative mortality. In the present study we sought t...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-1959-z
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:Radical lymph node dissection (LND) along the bilateral recurrent laryngeal nerve (RLN) is a surgically challenging procedure with a high rate of morbidity. Here, we assessed in a retrospective manner the adequacy of LND along the RLN performed with robot-assisted thoracoscopic esophagectomy (RATE) versus vid...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4179-0
更新日期：2018-02-01 00:00:00
abstract：:The aim of this study was to identify the risk factors for bacterial translocation and to determine the clinical significance of bacterial translocation in patients with colorectal cancer. Mesenteric lymph node sampling was performed to identify the presence of bacterial translocation in 75 patients with colorectal ca...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7576-0
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND:Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic disease of the breast. Despite the various treatment approaches described for this disease, a gold standard treatment modality has not yet been defined. In this study, the effect of topical steroids was reviewed and assessed in patients w...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3147-9
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:A precise understanding of anastomotic recurrence (AR) permits efficient surveillance and treatment strategies. This study aimed to evaluate the clinicopathologic characteristics of patients with AR undergoing curative resection for colorectal cancer (CRC), compare colonic with rectal tumors and investigate ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3663-2
更新日期：2017-01-01 00:00:00
abstract：:Although emergency department thoracotomy (EDT) is often considered a controversial "last chance" method of resuscitation, we hypothesized that EDT performed in a busy urban Level I trauma center has significant salvage rates despite the absence of traditional survival predictors. A retrospective review revealed that ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9392-9
更新日期：2008-04-01 00:00:00
abstract：:A group of 105 consecutive patients with venographically proved major acute deep vein thrombosis (DVT) were randomized in an open prospective study to evaluate the comparative efficacy and safety of a fixed dose of subcutaneous low-molecular-weight heparin (LMWH) and warfarin for the prevention of recurrent venous thr...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s002689900081
更新日期：1996-06-01 00:00:00
abstract：BACKGROUND:The aim of this study was to evaluate and investigate the complications of carotid endarterectomy (CEA) and carotid artery stenting (CAS) by performing a meta-analysis based on prospective randomized controlled trials (RCTs). METHODS:We performed a search of multiple electronic databases for RCTs containing...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-008-9862-8
更新日期：2009-03-01 00:00:00
abstract：:One hundred years ago, Edoardo Bassini said: "L'ernia é una malattia meccanica." Before that, Ambroise Paré (1598) and Joseph-Pierre Desault (1798) asserted the mechanical nature of strangulation. Beside strangulation, the most serious of all complications even today, I have studied huge hernias, which are natural com...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658869
更新日期：1989-09-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2634-8
更新日期：2014-10-01 00:00:00
abstract：:Mesosigmoidoplasty is a nonresective procedure for nongangrenous sigmoid volvulus. It aims to correct the main pathogenetic factor of this condition, the narrow but long mesosigmoid. Although it had been demonstrated by intraoperative measurements that this has indeed achieved its purpose, recurrent volvulus has been ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7010-z
更新日期：2003-12-01 00:00:00
abstract：:The most appropriate approach to treating hepatocellular carcinoma (HCC) in the caudate lobe has not yet been determined. A series of 197 patients who had undergone curative hepatic resection for HCC were analyzed. Fifteen patients had HCC in the caudate lobe: three in the Spiegel lobe (SP), three in the caudate proce...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7341-4
更新日期：2004-07-01 00:00:00
abstract：:This study compares the findings of conventional computed tomography (CT) and ultrasound (US) imaging in the preoperative evaluation of patients with abdominal aortic aneurysm (AAA). It also assesses the impact of preoperative CT-derived information on operative strategy. A prospective study was conducted of 96 patien...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900626
更新日期：1999-10-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05177-7
更新日期：2020-02-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0601-8
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:The role of neutrophil-to-lymphocyte ratio (NLR) and preoperative prediction model in gastric cancer is controversial, while postoperative prognostic models are available. This study investigated NLR as a preoperative prognostic indicator in gastric cancer. METHODS:We reviewed patients with primary gastric ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4510-4
更新日期：2018-08-01 00:00:00
abstract：:We have evaluated survival and tumor-related symptoms in the presence of mesenteric lymph node and liver metastases in relation to surgical procedures in 314 patients (148 women, mean age at diagnosis 61 years; 249 with liver metastases) treated for midgut carcinoid tumors. Of the operated patients, 46% presented with...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6630-z
更新日期：2002-08-01 00:00:00
abstract：BACKGROUND:Medullary thyroid carcinoma (MTC) accounts only for 1.4% of all thyroid malignancies in Japan. Since 1996, we have performed hemithyroidectomy, instead of total thyroidectomy, for sporadic nonhereditary MTC when the primary lesion is located in only one lobe. Regarding lymph node dissection, modified radical...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9795-2
更新日期：2009-01-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7887-9
更新日期：2005-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7728-x
更新日期：2005-06-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9285-y
更新日期：2008-01-01 00:00:00
abstract：:Variceal bleeding remains an important complication in extrahepatic portal vein thrombosis (EPVT). As for portal hypertension due to other etiologies, an elective treatment to decrease the risk of subsequent rebleeding is warranted. The results of the Sugiura-Futagawa procedure (SP) in 38 patients with variceal bleedi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00294409
更新日期：1994-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-007-9242-9
更新日期：2007-11-01 00:00:00
abstract：:Surgical innovation relies on patient safety and quality of life, which require a drastic iatrogenic impact reduction. A parallel development toward less invasive approaches has occurred in the field of surgery, interventional radiology, and endoscopy. Minimally invasive techniques provide unquestionable benefits to p...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2879-2
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with poor prognosis, as a majority of patients present with advanced disease. Current adjuvant strategies for metastatic patients include mitotane or other cytotoxic agents and carry a significant morbidity as well as a low (<10 %) 5-year sur...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2532-0
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:Primary hyperparathyroidism (PHPT) is a common endocrine disorder that predominantly affects patients >60 and is increasing in prevalence. Identifying risk factors for poor outcomes after parathyroidectomy in older adults will help tailor operative decision making. The impact of frailty on surgical outcomes ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4629-3
更新日期：2018-10-01 00:00:00
abstract：:The post-Soviet calamities of East European cardiac surgery highlight the spectrum of marked differences in overall operative capacities among individual post-Communist countries. A comparison with the level of cardiac surgery in Western Europe reveals the importance of continuing relief, comprising both educational a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7103-8
更新日期：2003-08-01 00:00:00
abstract：INTRODUCTION:Unilateral adrenal hyperplasia (UAH) is a rare, surgically correctable cause of primary hyperaldosteronism (PH). We report 2 cases and review the literature for cases of PH secondary to UAH successfully treated via surgery. METHODS:Two cases of UAH treated at our institution were retrospectively reviewed....
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-0594-8
更新日期：2007-01-01 00:00:00
abstract：:The rectal electrical activity recorded by electrorectogram (ERG) was studied in 22 chronically constipated subjects and 16 healthy volunteers. The latter had a mean (+/- SD) age of 42.6 +/- 8.5 years; 10 were men and 6 women. Of the 22 constipated patients, 14 had inertia-type constipation (IC; age 44.6 +/- 10.2 year...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00295930
更新日期：1995-09-01 00:00:00
