Abstract:
BACKGROUND:There is no clear consensus on the efficacy and safety of hyaluronate-carboxymethylcellulose membrane (Seprafilm) for preventing postoperative abdominal adhesion. This study is a meta-analysis of the available evidence. METHODS:A search of the MEDLINE, EMBASE, and the Cochrane Library identified eight studies that met the inclusion criteria for data extraction. Estimates of effectiveness were performed using fixed- and random-effects models. The effect was calculated as an odds ratio (OR) with 95% confidence intervals (CI) using the statistical software Review Manager Version 4.2. Level of significance was set at p < 0.05. RESULTS:Outcomes of 4203 patients were studied. The incidence of grade 0 adhesions among Seprafilm-treated patients was statistically significantly more than that observed among control group patients (OR 95%CI, 3.74-20.34; p < 0.01). There was no significant difference in the incidence of grade 1 adhesions between Seprafilm and control groups (OR 95%CI, 0.58-2.71; p = 0.56). The severity of grade 2 and grade 3 adhesions among Seprafilm-treated patients was significantly less than that observed among control group patients (OR 95%CI, 0.22-0.93; p = 0.03; OR 95%CI, 0.09-0.63; p < 0.01, respectively). The incidence of intestinal obstruction after abdominal surgery was not different between Seprafilm and control groups (OR 95%CI, 0.78-1.23; p = 0.84). Using Seprafilm significantly increased the incidence of abdominal abscesses (OR 95%CI, 1.06-2.54; p = 0.03) and anastomotic leaks (OR 95%CI, 1.18-3.50; p = 0.01). CONCLUSIONS:Our systematic review and meta-analysis showed that Seprafilm could decrease abdominal adhesions after general surgery, which may benefit patients, but could not reduce postoperative intestinal obstruction. At the same time, Seprafilm did increase abdominal abscesses and anastomotic leaks.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Zeng Q,Yu Z,You J,Zhang Qdoi
10.1007/s00268-007-9242-9subject
Has Abstractpub_date
2007-11-01 00:00:00pages
2125-31; discussion 2132issue
11eissn
0364-2313issn
1432-2323journal_volume
31pub_type
杂志文章,meta分析,评审abstract::Nineteen consecutive patients receiving renal transplants underwent prospective evaluation of their calcium homeostasis for 1 year after transplantation to characterize indices of hyperparathyroidism (HPT) amelioration. All but one underwent dialysis, and six had vitamin D supplementation before grafting. The rapid fa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900446
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Primary hyperparathyroidism (PHPT) is a common endocrine disorder that predominantly affects patients >60 and is increasing in prevalence. Identifying risk factors for poor outcomes after parathyroidectomy in older adults will help tailor operative decision making. The impact of frailty on surgical outcomes ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4629-3
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:The retained knife blade is an unusual and spectacular injury. The aim of this study was to review our experience with the management of such injuries. METHODS:A retrospective chart review of patients with retained knife blades treated at Groote Schuur Hospital Trauma Centre from January 1996 to December 20...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0514-4
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Utilization of breast reconstruction (BR) is low in many jurisdictions. We studied the geographical and surgical workforce factors that contribute to access and use of BR using a small area analysis approach with a geographical unit of analysis. METHODS:We linked administrative data from Ontario Canada to c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3060-2
更新日期:2015-08-01 00:00:00
abstract::The introduction of laparoscopic techniques for the management of biliary stone disease has expanded the therapeutic choices for surgeons confronted with choledocholithiasis. As new strategies emerge, the treatment of cholelithiasis and choledocholithiasis remains controversial. This paper discusses the options availa...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900531
更新日期:1998-11-01 00:00:00
abstract::Because of the rarity of adrenocortical carcinoma, survival rates and the prognosis for patients who have undergone operation are not well known. The purpose of the French Association of Endocrine Surgery was to evaluate these factors over an 18-year period. A trend study was associated to assess changes in the clinic...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0047-y
更新日期:2001-07-01 00:00:00
abstract:INTRODUCTION:Accidental intraoperative gallbladder perforation is a problem in laparoscopic surgery, especially in cases with incidental gallbladder carcinoma (IGBC). The question is whether intraoperative gallbladder perforation has a prognostic disadvantage or a retrieval bag provides protection against tumor dissemi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0163-7
更新日期:2009-10-01 00:00:00
abstract::Blood loss during liver transection and ischemia-reperfusion injury associated with hepatic inflow occlusion are significant drawbacks during liver surgery. Sixteen patients underwent liver resection using the Monopolar Floating Ball (FB) plus LigaSure (LS) diathermy without occlusion of the hepatoduodenal ligament (g...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-7167-5
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Although laparoscopic appendectomy (LA) is widely performed in many countries, LA for complicated appendicitis, which includes perforated or gangrenous appendicitis with or without localized or disseminated peritonitis, has not become a common practice yet. METHODS:We retrospectively analyzed the clinical r...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9843-y
更新日期:2009-02-01 00:00:00
abstract::The purpose of this study was to elucidate the function of the sphincter of Oddi (SO) in patients with juxtapapillary duodenal diverticula (JDDs). The SO function was evaluated by intraoperative biliary manometry in three groups of patients. Group 1 consisted of nine patients with JDDs and a dilated common bile duct (...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF00308647
更新日期:1995-03-01 00:00:00
abstract::A new technique utilizing miniaturized (2 mm) instrumentation to perform laparoscopic cholecystectomy (LC) is introduced. The safety and efficacy of this mini-LC were assessed. Fifty consecutive mini-LCs were performed using one 10-mm port and three 2-mm ports (cumulative port size 16 mm). A 2-mm fiberoptic video-lapa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/pl00013163
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:This study reviews the 15 year program of our Department of Pediatric Surgery for the treatment and follow-up of children born with a cleft in Benin and Togo. METHODS:We analyzed files of children born in Africa with a cleft. They were referred to us through a nongovernmental organization (NGO) between 1993...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1607-z
更新日期:2012-08-01 00:00:00
abstract::Although pancreatectomy is still performed in a few patients with pancreatic cancer, and nearly all patients who develop pancreatic cancer eventually die of their disease, significant improvements have been made recently. Pancreatectomy is now safer, with major morbidity (hemorrhage, pancreatic anastomotic leak, intra...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900599
更新日期:1999-09-01 00:00:00
abstract::Multiple organ failure (MOF) is considered to be the leading cause of death after severe trauma. Although there is extensive literature on MOF, little is known about the pattern, sequence, and onset of this clinical syndrome. The first goal of this clinical study was to define MOF; the second was to assess the typical...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900067
更新日期:1996-05-01 00:00:00
abstract:INTRODUCTION:Hypocalcemia is a well-known complication after total thyroidectomy. Studies have indicated that the presence of low postoperative parathyroid hormone (PTH) levels can predict hypocalcemia. However, definitive study designs are lacking. The aim of this study was to determine whether postoperative PTH alone...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4444-2
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma (HCC) is the most common primary liver cancer, causing approximately 660,000 deaths worldwide annually. The preferred treatment of HCC is surgical resection or orthotopic liver transplantation (OLT) for patients meeting specific criteria. For patients outside these criteria, options ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0954-x
更新日期:2011-08-01 00:00:00
abstract::The aim of the present study was to determine whether patients with the incident hospital diagnosis of primary hyperparathyroidism (PHPT) in Denmark during the period 1977-1993 had an increased mortality from cardiovascular disease and cancer compared to the rest of the Danish population. In a random sample of half of...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-7046-0
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:The follicular variant of papillary thyroid carcinoma (FVPTC) is the most common histologic subtype of papillary thyroid carcinoma (PTC). However, it is still controversial whether FVPTC should behave differently from classical PTC (CPTC). The present study aimed at evaluating any potential difference in c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0356-7
更新日期:2006-05-01 00:00:00
abstract::Over the past three decades Canada has developed an exemplary system of universal health care. However, current financial constraints threaten to undermine the very foundation of the system that represents Canada's respect for social justice. The first of these two articles (Part 1) discusses the unique characteristic...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00298897
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:Pheochromocytoma with synchronous ipsilateral adrenal cortical adenoma (PSCA) may present with mixed clinical, biochemical, and radiological features characteristic to each neoplasm subtype. METHODS:All patients with a pathological diagnosis of pheochromocytoma were evaluated for an ipsilateral cortical ade...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4110-8
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Little is known about the changes in prognostic factors after adjuvant S-1 monotherapy has become widespread as a standard of care for patients with gastric cancer (GC) in East Asia. The present study compared prognostic factors of patients with stage II/III GC treated with or without S-1 adjuvant to formula...
journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s00268-019-05198-2
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Nasogastric decompression has been routinely used in most major abdominal operations to prevent the consequences of postoperative ileus. The aim of the present study was to assess the necessity for routine prophylactic nasogastric or nasojejunal decompression after gastrectomy. METHODS:A prospective randomi...
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-006-0430-9
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Only few studies have compared laparoscopic total mesorectal excision (LTME) and open total mesorectal excision (OTME) for rectal cancer with follow-up longer than 5 years. The aim of this study was to compare 10-year oncologic outcomes after LTME and OTME for nonmetastatic rectal cancer. METHODS:We conduct...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3631-x
更新日期:2016-12-01 00:00:00
abstract::Acute acalculous cholecystitis (AAC) is a well known complication in severely traumatized patients. Existing data of AAC originate from retrospective analyses and episodic case reports. In a prospective study 45 polytraumatized patients admitted to our intensive care unit from January 1989 to June 1990 were clinically...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02067089
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:Treatment of peripherally located liver tumors with diaphragmatic invasion is technically demanding but does not preclude resection for cure. The aim of the present study was to compare patients undergoing combined liver and diaphragmatic resection with those submitted to hepatectomy alone so as to evaluate ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2083-9
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION:Sentinel lymph node biopsy (SLNB) is the standard of care for staging N0 primary early breast cancers (EBC). Patients in developing countries mostly present with large (LOBC) or locally advanced cancers (LABC) and are treated with neo-adjuvant chemotherapy (NACT). Accuracy of SLNB in staging stage III N0 a...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3222-2
更新日期:2016-07-01 00:00:00
abstract::Surgical treatment of adenomas may become necessary when the base of the polyp is too wide for snaring, increasing the risk of incomplete removal or perforation of the bowel wall. Suspicion of malignancy may also indicate surgery. Multiple adenomas not controlled by snare polypectomy can be treated by colectomy. The d...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01658955
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Macroscopic extrathyroidal extension (ETE) is a poor prognostic factor in papillary thyroid carcinoma (PTC). However, intraoperative inspection for ETE is often inaccurate and could lead the surgeon to misconstrue simple adhesion as gross ETE. Such confusion could result in more aggressive treatment than nec...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2034-5
更新日期:2013-07-01 00:00:00
abstract::We have evaluated survival and tumor-related symptoms in the presence of mesenteric lymph node and liver metastases in relation to surgical procedures in 314 patients (148 women, mean age at diagnosis 61 years; 249 with liver metastases) treated for midgut carcinoid tumors. Of the operated patients, 46% presented with...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6630-z
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:Patients with renal hyperparathyroidism (RHPT) are susceptible to major electrolyte fluctuations following parathyroidectomy, which may predispose them to early readmission. The purpose of this study is to evaluate risk factors for readmission in patients undergoing parathyroidectomy for RHPT. METHODS:Patie...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4823-3
更新日期:2019-02-01 00:00:00