Abstract：
BACKGROUND:In uremic patients, metabolism of 1-84 parathyroid hormone (PTH) and fragments are delayed, and in these patients, the usefulness of intraoperative PTH assay may be problematic. We evaluated the usefulness of the QuiCk-IntraOperative Bio-Intact PTH (QPTH) assay for uremic patients with secondary hyperparathyroidism who required total parathyroidectomy (PTx) with forearm autograft. The purpose of our study was to recognize whether QPTH in uremic patients was useful to determine during operation whether complete PTx had been achieved. METHODS:Forty-four patients who underwent initial PTx were enrolled in this study. Blood samples were drawn just after induction of general anesthesia (basal samples), immediately after removal of the last gland, and at 5, 10, 15, and 30 minutes, and at the first morning after PTx. The assay was performed immediately after sample collection. Reductions of PTH levels were evaluated and expressed in percentage of basal levels. RESULTS:The mean PTH levels in 41 patients, excluding 3 in whom the PTH level did not drop significantly (>60 pg/ml), measured by QPTH at anesthesia, 0, 5, 10, 15, and 30 minutes were 734.3, 104.7, 58.8, 37.4, 27.0, 16.3 pg/ml, corresponding to 100%, 17.1%, 9.3%, 5.8%, 4.1%, 2.4% of the preexcision values, respectively. If the cutoff value was defined as 10.8% at 10 minutes, the sensitivity was 100% and specificity 90%. When the QPTH level dropped to under 10.8% at 10 minutes, we could consider that all glands were removed. CONCLUSIONS:QPTH in uremic patients is very useful to determine whether complete PTx is achieved during operation.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Matsuoka S,Tominaga Y,Sato T,Uno N,Goto N,Katayama A,Uchida K,Takami Hdoi
10.1007/s00268-006-0601-8subject
Has Abstractpub_date
2007-04-01 00:00:00pages
824-31issue
4eissn
0364-2313issn
1432-2323journal_volume
31pub_type
杂志文章abstract：:The hospital records of 639 patients affected by primary gastric cancer who were consecutively admitted to our unit during the period 1981-1995 were reviewed. Overall 220 underwent total gastrectomy (38 palliative), 12 had resection of the gastric stump, 195 had distal subtotal gastrectomy (55 palliative), 78 had bypa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689910073
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND:Strong evidence has confirmed the benefit of laparoscopy in colorectal cancer resection but remains a challenging procedure. It is not clear that such promising results in selected patients translate into a favorable risk-benefit balance in real practice. We conducted a multicenter national observational reg...
journal_title：World journal of surgery
pub_type： 杂志文章,多中心研究
doi：10.1007/s00268-015-3050-4
更新日期：2015-08-01 00:00:00
abstract：:The most common causes of variceal bleeding are cirrhosis, schistosomiasis, and extrahepatic portal venous obstruction. The prognosis for an individual patient depends on the severity of the bleeding episode and the underlying liver function. Liver function is determined to a large extent by the underlying liver patho...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF00294397
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND:Surgical resection remains the treatment of choice for carotid body tumors (CBTs). Although perioperative complications such as carotid artery injury and neurological deficits occur infrequently, they can be devastating. The aim of this study was to evaluate whether clinical factors or preoperative imaging f...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3058-9
更新日期：2015-08-01 00:00:00
abstract：:Chondrosarcomas of the head and neck are uncommon. Over a 35-year period (1950-1985) at our institution, 557 patients had an established diagnosis of chondrosarcoma. In 28 (5%) of these patients, the tumor was located in the head and neck region. A retrospective analysis was performed in an attempt to accurately defin...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067021
更新日期：1992-09-01 00:00:00
abstract：BACKGROUND:The open surgical wound is exposed to cold dry ambient air, resulting in substantial heat loss through radiation, evaporation, and convection. At the same time, anesthesia decreases the patient's core temperature. Despite preventive measures, mild intraoperative hypothermia has been associated with postopera...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-012-1735-5
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:Exact tissue identification during parathyroidectomy is essential to successfully cure hyperparathyroidism. PTH level determination from tissue aspirates has been advocated as a "biochemical frozen section" for parathyroid tissue identification. We investigated the sensitivity and specificity of this method ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0351-5
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:Below knee amputation (BKA) is often required in patients with critical limb ischemia. When such a procedure fails, an above knee revision (AKA) is required. This can cause further complications in this group of patients, who already have a high incidence of medical co-morbidities. METHODS:Case records of 4...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0737-y
更新日期：2006-06-01 00:00:00
abstract：:The present prospective clinical study was carried out to investigate the effect of age on mortality, morbidity, and readmission rates after coronary artery bypass grafting (CABG). Data on 1131 consecutive CABG patients were collected in a surgical center and in all 18 secondary referral hospitals up to 3 months after...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7033-5
更新日期：2003-12-01 00:00:00
abstract：:This study assessed the results of surgical treatment for Graves' disease in our hospital and examined the relationship between the values of thyroid stimulating hormone (TSH) receptor antibodies and postoperative thyroid function. From 1983 to 1988, subtotal thyroidectomy was performed in 313 patients with Graves' di...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067345
更新日期：1992-07-01 00:00:00
abstract：BACKGROUND:A PubMed search of the biomedical literature was carried out to systematically review the role of laparoscopy in colonic diverticular disease. All original reports comparing elective laparoscopic, hand-assisted, and open colon resection for diverticular disease of the colon, as well as original reports evalu...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-012-1872-x
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:The purpose of the present study was to develop and validate a multidimensional, surgery-specific workload measure (the SURG-TLX), and to determine its utility in providing diagnostic information about the impact of various sources of stress on the perceived demands of trained surgical operators. As a wide r...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1141-4
更新日期：2011-09-01 00:00:00
abstract：:This prospective study was instituted to assess whether the use of the on-pump method or the off-pump method affects changes in health-related quality of life (QOL) as evaluated a year after coronary artery bypass graft (CABG) surgery. Data including preoperative risk factors and postoperative morbidity up to discharg...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7486-1
更新日期：2004-10-01 00:00:00
abstract：BACKGROUND:In the past decade, Enhanced Recovery after Surgery (ERAS) protocols have been implemented in several fields of surgery. With these protocols, a faster recovery and shorter hospital stay can be accomplished without an increase in morbidity or mortality. The purpose of this study was to review systematically ...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-013-2044-3
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Donor variational arteries often require complex reconstruction. METHODS:We analysed the incidence of different variations, types of arterial reconstructions and their impact on post-operative results from 409 patients undergoing liver transplantation at Karolinska Institute between 2007 and 2015. RESULTS:...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05406-4
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:This is a baseline assessment of surgical capacity in the Federal Capital Territory (FCT), in preparation for the creation of a National Surgical, Obstetric, Anesthesia, and Nursing Plan. METHODS:In October 2017, all 10 of the 11 secondary hospitals in FCT that provide surgical and/or obstetric care were su...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4835-z
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:The aim of the present study was to determine whether early oral feeding after curative resection for gastric cancer can be tolerated and whether it has an effect on recovery. METHODS:From September 2007 to January 2008, we provided early postoperative oral feeding for 35 patients who underwent curative dis...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0009-3
更新日期：2009-07-01 00:00:00
abstract：:We have previously demonstrated that one dimensional (1D) proton (1H) magnetic resonance spectroscopy (MRS) can distinguish normal thyroid tissue from thyroid carcinoma using a spectral ratio of peak intensity at 1.7 ppm/0.9 ppm. Two dimensional (2D) 1H-MRS allows identification of specific molecules that have overlap...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900128
更新日期：1996-09-01 00:00:00
abstract：BACKGROUND:Despite wide acknowledgement of the importance of sarcopenia and prognostic markers such as the neutrophil-to-lymphocyte ratio, the impact on cancer patient survival of the timing of sarcopenia's emergence and its severity is not well understood, nor is the association between sarcopenia and prognostic marke...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05344-w
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:Unilateral vocal fold paralysis (UVFP) may present as an uncommon complication of extralaryngeal neoplasms, requiring diagnostic scrutiny to seek occult tumors or diseases. The aim of this study was to examine the utility of computed tomography (CT) in evaluating adult UVFP of unknown etiology. METHODS:From...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-1991-z
更新日期：2013-06-01 00:00:00
abstract：:Jejunostomy is a surgical procedure by which a tube is situated in the lumen of the proximal jejunum, primarily to administer nutrition. There are many techniques used for jejunostomy: longitudinal Witzel, transverse Witzel, open gastrojejunostomy, needle catheter technique, percutaneous endoscopy, and laparoscopy. Th...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/pl00012353
更新日期：1999-06-01 00:00:00
abstract：BACKGROUND:Pain syndromes of somatic and neuropathic origin are considered to be the main causes of chronic pain after open inguinal hernia repair. Nerve-identification during open hernia repair is suggested to be associated with less postoperative chronic pain. The aim of this study was to define clinically relevant s...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0376-y
更新日期：2007-02-01 00:00:00
abstract：BACKGROUND:Parathyroid glands (PGs) can be particularly hard to distinguish from surrounding tissue and thus can be damaged or removed during thyroidectomy. Postoperative hypoparathyroidism is the most common complication after thyroidectomy. Very recently, it has been found that the parathyroid tissue shows near-infra...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3571-5
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:Ultrasound (US) and sestamibi (MIBI) are traditionally considered positive or negative. The purpose of this study was to define and test a new scoring system for MIBI and US and to determine whether this can improve their accuracy for primary hyperparathyroidism. METHODS:This is a prospective study of 200 c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1666-1
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:A precise understanding of anastomotic recurrence (AR) permits efficient surveillance and treatment strategies. This study aimed to evaluate the clinicopathologic characteristics of patients with AR undergoing curative resection for colorectal cancer (CRC), compare colonic with rectal tumors and investigate ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3663-2
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Measurement of the parathyroid hormone (PTH) level following total thyroidectomy (TTx) may allow prediction of postoperative hypocalcemia. We present an algorithmic method of managing hypocalcemia pre-emptively, based on the PTH level 1 h after operation. MATERIALS AND METHODS:We examined 423 consecutive pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0348-0
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:The incidence, pattern, and severity of sleep disturbance and cognitive dysfunction has not been well characterized for patients with primary hyperparathyroidism (PHPT). There is no agreement on the mechanism of the development or resolution of such symptoms, and in no previous study has cerebral activity be...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0361-x
更新日期：2006-05-01 00:00:00
abstract：BACKGROUND:Treatment of peripherally located liver tumors with diaphragmatic invasion is technically demanding but does not preclude resection for cure. The aim of the present study was to compare patients undergoing combined liver and diaphragmatic resection with those submitted to hepatectomy alone so as to evaluate ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2083-9
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Fast-track surgery (FTS) is a promising program for surgical patients and has been applied to several surgical diseases. FTS is much superior to conventional perioperative care. Our aim was to evaluate and compare the safety and efficacy of FTS and conventional perioperative care for patients undergoing gast...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-014-2690-0
更新日期：2014-12-01 00:00:00
abstract：:The moral dilemmas faced by surgeons worldwide who treat patients infected with the human immunodeficiency virus (HIV) can be viewed against the background of experience in sub-Saharan countries, where the community prevalence is in excess of 25% (90% of hospital inpatients). When seeking consent for an HIV test befor...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7101-x
更新日期：2003-08-01 00:00:00
