Abstract：
BACKGROUND:A precise understanding of anastomotic recurrence (AR) permits efficient surveillance and treatment strategies. This study aimed to evaluate the clinicopathologic characteristics of patients with AR undergoing curative resection for colorectal cancer (CRC), compare colonic with rectal tumors and investigate the risk factors related to AR. METHODS:A single-institution, retrospective cohort of 9024 patients who underwent curative surgery for CRC between 2000 and 2010 was enrolled. Patients were classified into AR group (n = 53) or non-AR group (n = 8971) and were also characterized by tumor location. RESULTS:The AR group was independently associated with old age (p = 0.046), advanced N stage (p = 0.003), the rectum (p = 0.001), a large tumor (p = 0.001) and mucinous differentiation (MU) (p = 0.026). In colon cancers, the AR group (n = 20) was independently associated with MU (p = 0.022) and lymphovascular invasion (LVI) (p = 0.001). In rectal cancers, the AR group (n = 33) was independently associated with N2 stage (p = 0.007) and a large tumor (p < 0.001). AR is a burden to patients and physicians because these tumors have a poor prognosis and more advanced pathologic stages than the primary tumors. However, N0 stage and curative resection of an AR tumor (p = 0.001 and p < 0.001, respectively) were found to be independently associated with improved survival in a Cox regression model. CONCLUSION:AR is independently associated with the rectum. In colon cancers, MU and LVI are independent risk factors for AR. In rectal cancers, a large tumor and N2 stage are independent risk factors for AR. Although AR shows a poor prognosis, early detection and curative resection may lead to an improved survival.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Jung WB,Yu CS,Lim SB,Park IJ,Yoon YS,Kim JCdoi
10.1007/s00268-016-3663-2subject
Has Abstractpub_date
2017-01-01 00:00:00pages
285-294issue
1eissn
0364-2313issn
1432-2323pii
10.1007/s00268-016-3663-2journal_volume
41pub_type
杂志文章abstract：BACKGROUND:Thoracoscopic repair of esophageal atresia is considered to be one of the more advanced pediatric surgical procedures, and it undoubtedly has a learning curve. This is a single-center study that was designed to determine the learning curve of thoracoscopic repair of esophageal atresia. METHODS:The study inv...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1651-8
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:The 'gentle' handling of tissue (i.e., 'respect for tissue') is a fundamental aspect of surgical performance and learning. To date, there have been no methodological assessments that quantitatively measure 'gentleness.' Therefore, the aims of this study were (1) to propose a novel metric for gentle surgical ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05018-7
更新日期：2019-09-01 00:00:00
abstract：:During the three decades since the recognition of the Zollinger-Ellison syndrome (ZES), major progress has been made in the diagnosis and treatment of this disease. However, the many failed operations in patients with ZES, the existence of primary lymph node gastrinomas, and the surgical approach of patients with ZES ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01655107
更新日期：1993-07-01 00:00:00
abstract：BACKGROUND:Single-incision laparoscopic cholecystectomy (SILC) has been increasingly performed recently. Although it seems plausible that SILC will be associated with less pain compared to standard 4-port laparoscopic cholecystectomy (LC), there is currently no conclusive comparative study on the postoperative pain iss...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0842-4
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Traditional perioperative care for colonic surgery in elderly patients is associated with increased morbidity and mortality compared to that of younger patients. Although multimodal perioperative rehabilitation has evolved as a valid concept to improve postoperative outcome, its use has not yet been establis...
journal_title：World journal of surgery
pub_type： 杂志文章,多中心研究
doi：10.1007/s00268-009-0018-2
更新日期：2009-08-01 00:00:00
abstract：BACKGROUND:Continuous vagal intraoperative neuromonitoring (CIONM) of the recurrent laryngeal nerve (RLN) may reduce the risk of RLN lesions during high-risk endocrine neck surgery such as operation for large goiter potentially requiring transsternal surgery, advanced thyroid cancer, and recurrence. METHODS:Fifty-five...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3368-y
更新日期：2016-03-01 00:00:00
abstract：:Necrotizing lesions of the soft tissues are grave entities not infrequently seen in daily surgical practice. They may occur with epidemic proportions after natural disasters, representing a serious challenge to the surgeon since they are characteristically associated with high mortality rates unless an early diagnosis...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01659058
更新日期：1991-03-01 00:00:00
abstract：BACKGROUND:Medullary thyroid carcinoma (MTC) originates from calcitonin-producing cells of the thyroid. In 2009, we published our first report on the biological characteristics and prognosis of 118 MTC patients. Herein, we enrolled a larger number of patients with longer follow-up periods to further study the biologica...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4738-z
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Laparoscopic incisional and ventral hernia repair (LIVHR) is an alternative approach to conventional open incisional and ventral hernia repair (OIVHR). A consensus on outcomes of LIVHR when compared with OIVHR has not been reached. METHODS:As the basis for the present study, we performed a systematic review...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-014-2578-z
更新日期：2014-09-01 00:00:00
abstract：:Unquestionably, progress has been made in the early detection and early treatment of primary liver cancers (PLCs), although most remain unresectable, mainly because the cancer is advanced and coexists with liver cirrhosis, particularly in Oriental patients. Thanks to the progress of regional cancer therapy, a multidis...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00316979
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:Medullary thyroid carcinoma (MTC) accounts only for 1.4% of all thyroid malignancies in Japan. Since 1996, we have performed hemithyroidectomy, instead of total thyroidectomy, for sporadic nonhereditary MTC when the primary lesion is located in only one lobe. Regarding lymph node dissection, modified radical...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9795-2
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:Ultrasound (US) and sestamibi (MIBI) are traditionally considered positive or negative. The purpose of this study was to define and test a new scoring system for MIBI and US and to determine whether this can improve their accuracy for primary hyperparathyroidism. METHODS:This is a prospective study of 200 c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1666-1
更新日期：2012-10-01 00:00:00
abstract：:The safe and permissible limits of hepatectomy in obstructive jaundice patients and the usefulness of preoperative portal embolization (PE) for increasing the limit for safe hepatectomy were examined. We classified 416 patients with hepatectomy performed over 9 years under the following headings: normal liver function...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7128-7
更新日期：2004-05-01 00:00:00
abstract：:Intraabdominal bleeding, the most life-threatening complication following pancreaticoduodenectomy (PD), most often is associated with failure of a pancreaticojejunostomy anastomosis or with intraabdominal infection. We investigated whether placement of an omental flap around the splanchnic vessels in PD could reduce t...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7900-3
更新日期：2005-09-01 00:00:00
abstract：:The pylorus-preserving pancreaticoduodenectomy (PPPD) is an alternative to the standard Whipple resection in the treatment of chronic pancreatitis. The operation is safe and can be performed with a low mortality rate. The most common early complication is delayed gastric emptying, which occurs in 25% to 30% of patient...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-003-7240-0
更新日期：2003-11-01 00:00:00
abstract：INTRODUCTION:Mechanical bowel obstruction cases constitute an important place in emergency health care services. In this study, bowel obstructions caused by intra-abdominal tumors were compared with those without tumoral causes. PATIENTS AND METHODS:A total of 155 cases of mechanical bowel obstruction diagnosed were r...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0440-z
更新日期：2006-07-01 00:00:00
abstract：:A wide range of clinical symptoms and signs are observed with venous thrombosis. Nonetheless, clinical diagnosis has been found to be unreliable and accurate diagnostic methods must be used before potent therapy such as anticoagulation is instituted, since the complications of treatment themselves can be life-threaten...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658825
更新日期：1990-09-01 00:00:00
abstract：BACKGROUND:Strictures at the pharyngoesophageal junction represent a subgroup of corrosive esophageal strictures requiring a specialized management approach. Non-dilatable cricopharyngeal strictures need surgical intervention. We report the use of the sternocleidomastoid muscle myocutaneous inlay flap (SCMMIF) for reco...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9120-5
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Chagas disease is a serious public health issue in South and Central America due to its high prevalence, morbidity, and mortality. The esophageal form of the disease leads to achalasia and consequent megaesophagus. In advanced or recurrent cases of megaesophagus, there is no consensus for which of three esta...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2445-3
更新日期：2014-06-01 00:00:00
abstract：:A large number of families with familial isolated hyperparathyroidism (FIHP) have been reported. We wanted to determine if some of these families represent early manifestations of full-blown syndromes such as multiple endocrine neoplasia type 1 (MEN-1), as early identification may alter surgical and medical management...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6617-9
更新日期：2002-08-01 00:00:00
abstract：BACKGROUND:Pain syndromes of somatic and neuropathic origin are considered to be the main causes of chronic pain after open inguinal hernia repair. Nerve-identification during open hernia repair is suggested to be associated with less postoperative chronic pain. The aim of this study was to define clinically relevant s...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0376-y
更新日期：2007-02-01 00:00:00
abstract：:The well-known poor prognosis of proximal bile duct cancer is due to its unfortunate anatomical location and its late diagnosis. Successful tumor resection, which is considered to be optimal treatment, depends on many factors. Eighty-eight patients suffering from proximal bile duct cancer underwent surgical exploratio...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-6656-x
更新日期：2003-06-01 00:00:00
abstract：:Surgery is the main modality in the treatment of hepatic hydatid disease. In this report, a laparoscopic surgical method is described, and the results in the first 16 cases are presented. The method involves the use of an aspirator-grinder apparatus that achieves effective evacuation of viable cyst contents with the p...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00295914
更新日期：1995-09-01 00:00:00
abstract：:Individuals in clinical training programs concerned with critical medical care must learn to manage clinical cases effectively as a member of a team. However, practice on live patients is often unpredictable and frequently repetitive. The widely substituted alternative for real patients-high-fidelity, manikin-based si...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9354-2
更新日期：2008-02-01 00:00:00
abstract：:The acid-base balance from the postoperative day (POD) 1 to POD 3 after cirrhotic liver resection was investigated in relation to operative outcome by conducting a retrospective study on the changes in arterial ketone body ratio (AKBR), which reflects the hepatic mitochondrial redox state, and arterial blood gas analy...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01655722
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Sepsis is common in surgical patients, and its presence influences the outcomes in those to undergo surgery. Factors such as advanced age, presence of comorbidities and many other conditions increase mortality in surgical patients with sepsis. The sequential organ failure assessment (SOFA) score simplified i...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05708-7
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:This is the fourth updated Enhanced Recovery After Surgery (ERAS®) Society guideline presenting a consensus for optimal perioperative care in colorectal surgery and providing graded recommendations for each ERAS item within the ERAS® protocol. METHODS:A wide database search on English literature publication...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-018-4844-y
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Finnmark County is the northernmost county in Norway. For several decades, the rate of mortality after injury in this sparsely inhabited region has remained above the national average. Following documentation of this discrepancy for the period 1991-1995, improvements to the trauma system were implemented. Th...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1102-y
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:We determined the rates of initial lymph node metastasis following curative resection of mass-forming type-intrahepatic cholangiocarcinoma (ICC) in patients with and without hepatitis virus infection. METHODS:We enrolled 87 patients between January 2000 and December 2013 with ICC without preo...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3843-0
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:Nasogastric decompression has been routinely used in most major abdominal operations to prevent the consequences of postoperative ileus. The aim of the present study was to assess the necessity for routine prophylactic nasogastric or nasojejunal decompression after gastrectomy. METHODS:A prospective randomi...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-006-0430-9
更新日期：2007-01-01 00:00:00
