Pylorus-preserving pancreaticoduodenectomy in the treatment of chronic pancreatitis.

Abstract:

:The pylorus-preserving pancreaticoduodenectomy (PPPD) is an alternative to the standard Whipple resection in the treatment of chronic pancreatitis. The operation is safe and can be performed with a low mortality rate. The most common early complication is delayed gastric emptying, which occurs in 25% to 30% of patients, and generally results in longer hospital stays than the standard Whipple procedure. Follow-up studies show that both operations are equally effective in relieving pain in approximately 75% of selected patients. In the long term, the PPPD successfully preserves physiologic gastric emptying, but at the cost of a higher marginal ulceration rate. The purported nutritional advantages of the PPPD over the classic Whipple resection have not been clearly established. At present, the PPPD is the procedure of choice for patients with chronic pancreatitis requiring panceraticoduodenectomy. Based on available information, this recommendation appears to arise form the fact that the PPPD is less radical than the regular Whipple procedure, and some surgeons find it technically easier. Our experience fails to show a distinct superiority of the PPPD over the Whipple operation.

journal_name

World J Surg

journal_title

World journal of surgery

authors

Jimenez RE,Fernandez-Del Castillo C,Rattner DW,Warshaw AL

doi

10.1007/s00268-003-7240-0

keywords:

subject

Has Abstract

pub_date

2003-11-01 00:00:00

pages

1211-6

issue

11

eissn

0364-2313

issn

1432-2323

journal_volume

27

pub_type

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