Abstract:
BACKGROUND:Laparoscopic intersphincteric resection (ISR) after neoadjuvant chemoradiation is helpful in the management of patients with low rectal cancer. With the advent of this technique, the need for performance of abdominoperineal resection seems to have decreased in patients with very low rectal tumors. The aim of the present study was to evaluate the feasibility, the functional outcome, and the short-term oncologic outcomes of laparoscopic ISR for low rectal adenocarcinoma at our institution. METHODS:We retrospectively reviewed the data of 111 consecutive patients who underwent laparoscopic ISR for low rectal adenocarcinoma between July 2005 and December 2009. Demographic status, surgical outcomes, functional outcome data, and oncologic outcome data were collected. RESULTS:The mean distance of the tumor from the anal verge was 3.4 cm (range: 1-5 cm). The mean operative time was 214.7 min (range, 150-450 min). The mean distal resection margin was 1.3 ± 1.1 cm. Morbidity occurred in 24 patients (21.6%), including anastomotic leakage in 2 patients (1.8%). The mean Wexner continence score after stoma repair was 7.5 ± 2.7 (range: 2 ~ 19), and 9.8 in total ISR, 7.3 in partial ISR (P = 0.071). The 3-year overall survival rate was 92.8%, and the 3-year disease-free survival rate was 73.0%. Local recurrence was noted in 6 of the 111 patients with TNM stage I to III (5.4%). The patients with lesions at 2 cm to the dentate line had a 7.07-fold greater risk of local recurrence, including a 13.42-fold greater risk of lateral pelvic wall recurrence and perineal recurrence (95% Confidence interval [CI], 1.141-158.006; P = 0.009) than in those who had lesions more than 2 cm from the anal verge (95% CI, 1.290-38.832; P = 0.011). CONCLUSIONS:Laparoscopic ISR after neoadjuvant chemoradiation can be recommended as a technically feasible, minimally invasive, and a sphincter-saving procedure with acceptable functional and short-term oncologic outcomes in patients with very low rectal cancer.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Lim SW,Huh JW,Kim YJ,Kim HRdoi
10.1007/s00268-011-1277-2subject
Has Abstractpub_date
2011-12-01 00:00:00pages
2811-7issue
12eissn
0364-2313issn
1432-2323journal_volume
35pub_type
杂志文章abstract::Quality of life is an important outcome measure following surgery for ulcerative colitis. Quality of life incorporates not only the physical or functional outcome; it also considers the emotional and social well-being of patients. Quality of life may be measured using disease-specific or generic quality of life measur...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900400
更新日期:1998-04-01 00:00:00
abstract:BACKGROUND:Nodal involvement of papillary thyroid carcinoma (PTC) commonly occurs in the paratracheal region and the internal jugular chain. Lymph node metastasis in the parapharyngeal space (PPS) is rare. In this report, we describe our experience and surgical outcomes of patients with PPS metastasis of PTC. METHODS:...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3321-0
更新日期:2016-02-01 00:00:00
abstract:IMPORTANCE:In resource-limited settings, identification of successful and sustainable task-shifting interventions is important for improving care. OBJECTIVE:To determine whether the training of lay people to take vital signs as trauma clerks is an effective and sustainable method to increase availability of vital sign...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4121-5
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Breast cancer in young women is uncommon, but when it does occur it has been reported to have aggressive biological characteristics. The incidence of breast cancer peaks at age 40 in Hong Kong Chinese women, earlier than in Caucasians. This study is the first to report the tumor characteristics and managemen...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9589-6
更新日期:2008-12-01 00:00:00
abstract::The release of the neuronal protein S-100B into the circulation has been suggested as an early indication of cellular brain damage. The objective of this prospective pilot study was to determine S-100B serum levels in patients undergoing cross-clamping during carotid endarterectomy (CEA) and to correlate the results w...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6547-6
更新日期:2002-10-01 00:00:00
abstract::A variety of techniques have been used for surgical treatment of hepatic hydatid cysts. The objective of this study is to describe the technique of diaphragm myoplasty, and to present our experience in the treatment of selected patients with hydatid disease of the liver by means of this alternative surgical technique....
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6558-3
更新日期:2003-02-01 00:00:00
abstract::Intraabdominal hypertension (IAH) and abdominal compartment syndrome (ACS) have detrimental effects on all organ systems and are associated with significant morbidity and mortality. In recent years, the diagnosis and management of these syndromes has evolved tremendously, and the importance of comprehensive strategies...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0003-9
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:The present study is designed to determine the feasibility and impact of the introduction of laparoscopic wedge resection as a surgical option for the treatment of suspected small/medium-sized (<7 cm) gastric gastrointestinal stromal tumors (GISTs). METHODS:The study involved a retrospective review of 53 co...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0590-5
更新日期:2010-08-01 00:00:00
abstract::Lower esophageal sphincter pressure has been assessed pre-operatively, intra-operatively,and more than 6 months postoperatively in 34 patients having antireflux surgery for gastro-esophageal reflux disease. The sphincter pressures associated with the outcome in relation to pH measured reflux and the symptoms of recurr...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02071543
更新日期:1992-03-01 00:00:00
abstract::Adenocarcinomas of the esophagogastric junction (AEG) are now recognized as a separate tumor entity with increasing incidence. The aim of the present study was to evaluate whether positron emission tomography (PET) using the glucose analog F-18-fluorodeoxyglucose (FDG) can be used for metabolic characterization of thi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-7058-9
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Team familiarity has been shown to be important for operative efficiency and number of complications, but it is unclear for which types of operations and for which team members familiarity matters the most. The objective of this study is to further our understanding of familiarity in the OR by quantifying th...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05657-1
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:It is now generally believed that regulatory T cells (Tregs) play an important role in peripheral tolerance, and a defect in Tregs is considered one of the most important factors in the induction of various kinds of autoimmune disease including ulcerative colitis (UC). Here, we examined the change in frequen...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0301-9
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:This study evaluated the impact of tumor regression grading (TRG) and other pathologic variates in a cohort of rectal carcinoma patients treated with neoadjuvant chemoradiotherapy (CRT). The value of a grading less than pCR for predicting survival is unknown. Tumor budding has not been systematically studied...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1409-8
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Accurate presurgical assessment is important to anticipate postoperative complications, especially in the growing proportion of elderly cancer patients. We designed a study to define which comorbid conditions at the time of diagnosis predict complications after surgery for colorectal cancer. PATIENTS:A rand...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0711-8
更新日期:2007-01-01 00:00:00
abstract::Telomerase adds hexameric repeats of 5'-TTAGGG-3' to the ends of chromosomal DNA (telomere) and has been implicated in cell immortalization and cellular senescence. The aim of this study was to measure quantitatively the telomerase activity and human telomerase RNA component (hTR) content in gastric cancer and to exam...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002680010246
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:It has been thirty years since Bianchi introduced the technique that made intestinal lengthening possible. The last three decades have seen lengthening procedures established as vital components of intestinal rehabilitation programs. The goal of the present study was to use a systematic literature review to ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-012-1879-3
更新日期:2013-03-01 00:00:00
abstract::Experience with the use of nylon fishing line for surgical sutures has been reported from several African countries. A recent publication suggested that fishing line and an injection needle may provide an atraumatic suture that is especially suitable for intracutaneous skin closures. This article provides further empi...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00268-003-7323-y
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:New medical therapies available to ulcerative colitis (UC) patients have influenced operative mortality for patients requiring colectomy. We sought to examine trends in treatment and outcome for UC patients treated surgically. METHODS:A review of 36,447 UC patients from the Nationwide Inpatient Sample was p...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0910-9
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:The extent to which obesity and genetics determine postoperative complications is incompletely understood. METHODS:We performed a retrospective study using two population cohorts with electronic health record (EHR) data. The first included 736,726 adults with body mass index (BMI) recorded between 1990 and ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05202-9
更新日期:2020-01-01 00:00:00
abstract::The angiogenic factor called vascular endothelial growth factor (VEGF)-D is a ligand for VEGF receptor-2 (VEGFR-2/KDR) and receptor-3 (VEGFR-3/Flt-4). It is implicated in the development of lymphatic vessels and promotion of lymphatic metastasis. The purpose of this study was to investigate the prognostic significance...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0076-z
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Surgical care is critical to establish effective healthcare systems in low- and middle-income countries, yet the unmet need for surgical conditions is as high as 65% in Ugandan children. Financial burden and geographical distance are common barriers to help-seeking in adult populations and are unmeasured in ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4691-x
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:The aim of this study was to report on the application of a minimally invasive technique to the radical extirpation of primary and recurrent pilonidal disease. This technique does not require specific equipments, is ordinarily performed under local anesthesia on an outpatient basis, and provides optimal cosm...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05313-3
更新日期:2020-04-01 00:00:00
abstract::This retrospective study reports our experience managing 78 patients with adenocarcinoma of the esophagus and gastroesophageal junction operated between January 1982 and December 1996. Altogether 18 patients presented with stage I and II disease, and 60 patients had stage III and IV disease at presentation; 56 patient...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/pl00013179
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:The splintering of general surgery into subspecialties in the past decade has brought into question the relevance of a continued emphasis on traditional general surgical training. With the majority of trainees now expressing a preference to subspecialise early, this study sought to identify if the requiremen...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2890-7
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:The venous vascular anatomy of the caudate lobe is exceptional. The purpose of this study was to assess portal inflow and venous outflow volumes of the caudate lobe. METHODS:Extrahepatic (provided by the first-order branches) versus intrahepatic (provided by the second- to third-order branches) portal inflow...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3791-8
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Right hepatectomy with caudate lobectomy (RHx) is considered an appropriate procedure for Bismuth type I/II perihilar cholangiocarcinoma in terms of its anatomical and oncological aspect. However, validity of left hepatectomy with caudate lobectomy (LHx) concomitant with arterial resection and reconstruction...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4833-1
更新日期:2019-03-01 00:00:00
abstract::Intraabdominal bleeding, the most life-threatening complication following pancreaticoduodenectomy (PD), most often is associated with failure of a pancreaticojejunostomy anastomosis or with intraabdominal infection. We investigated whether placement of an omental flap around the splanchnic vessels in PD could reduce t...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7900-3
更新日期:2005-09-01 00:00:00
abstract::Innovation is responsible for most advances in the field of surgery. Innovative approaches to solving clinical problems have significantly decreased morbidity and mortality for many surgical procedures, and have led to improved patient outcomes. While innovation is motivated by the surgeon's expectation that the new a...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2568-1
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:The Acute Care Surgery (ACS) model was developed as a dedicated service for the provision of 24/7 nontrauma emergency surgical care. This systematic review investigated which components are essential in an ACS model and the state of implementation of ACS models worldwide. METHODS:A literature search was con...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-020-05536-9
更新日期:2020-08-01 00:00:00
abstract::Although peptic gastroduodenal ulcers are rarely treated surgically today, when surgery is required a laparoscopic approach is possible with its well known advantages. The most widely used technique is vagotomy by various modalities. Training in laparoscopy requires good instrumentation to avoid complications. Vagotom...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689910044
更新日期:2000-03-01 00:00:00