Trends in the surgical treatment of ulcerative colitis over time: increased mortality and centralization of care.

Abstract:

BACKGROUND:New medical therapies available to ulcerative colitis (UC) patients have influenced operative mortality for patients requiring colectomy. We sought to examine trends in treatment and outcome for UC patients treated surgically. METHODS:A review of 36,447 UC patients from the Nationwide Inpatient Sample was performed, comparing the pre-monoclonal antibody era (1990-1996) to the present-day era (2000-2006). Patients treated with total colectomy with ileostomy or proctocolectomy with ileal pouch were reviewed for outcome measures and practice setting (rural, urban non-teaching, urban teaching). Our main outcome measures were in-hospital mortality, length of stay, and total charges. RESULTS:Total colectomy (n = 30,362) was performed five times more often than proctocolectomy (n = 6,085). When comparing the two study periods, mortality after total colectomy increased 3.8% to 4.6% (p = 0.0003). This difference was primarily due to increasing mortality in later years; when 1995-1996 was compared to 2005-2006, mortality increased from 3.6% to 5.6% (p < 0.0001). There were no deaths in the proctocolectomy group (p < 0.0001). The distribution by practice setting shifted over the two study periods, decreasing in rural (7.0% to 4.8%) and urban non-teaching (43.7% to 28.4%) centers, and increasing in urban teaching centers (49.3% to 66.8%). The total inflation-adjusted charges per patient increased significantly ($34,638 vs. $43,621; p < 0.0001). CONCLUSIONS:The mortality rate after total colectomy is increasing, and the difference is accentuated in the years since widespread use of monoclonal antibody therapy. The care of these patients is being shifted to urban teaching centers and is becoming more expensive.

journal_name

World J Surg

journal_title

World journal of surgery

authors

Ellis MC,Diggs BS,Vetto JT,Herzig DO

doi

10.1007/s00268-010-0910-9

subject

Has Abstract

pub_date

2011-03-01 00:00:00

pages

671-6

issue

3

eissn

0364-2313

issn

1432-2323

journal_volume

35

pub_type

杂志文章
  • Burn shock resuscitation.

    abstract::The goal of fluid resuscitation in the burn patient is maintenance of vital organ function at the least immediate or delayed physiological cost. To optimize fluid resuscitation in severely burned patients, the amount of fluid should be just enough to maintain vital organ function without producing iatrogenic pathologi...

    journal_title:World journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1007/BF02067109

    authors: Warden GD

    更新日期:1992-01-01 00:00:00

  • Telesurgery: remote knowledge translation in clinical surgery.

    abstract::Dissemination of new surgical knowledge, skills, and techniques across the wide spectrum of practicing surgeons in the community is often difficult and slow. This is even more problematic in countries such as Canada, where geographic distances separate a large portion of community surgeons from the large teaching cent...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-007-9076-5

    authors: Anvari M

    更新日期:2007-08-01 00:00:00

  • Prevention of subcutaneous seroma formation in open ventral hernia repair using a new low-thrombin fibrin sealant.

    abstract:BACKGROUND:Seroma formation is a frequent postoperative complication following open ventral hernia repair (OVHR), especially in cases requiring wide subcutaneous dissection (WSD). The aim of this study was to evaluate the effectiveness of a new low-thrombin fibrin sealant for seroma prevention. METHODS:A total of 60 c...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-014-2691-z

    authors: Köhler G,Koch OO,Antoniou SA,Lechner M,Mayer F,Emmanuel K

    更新日期:2014-11-01 00:00:00

  • Incidental gallbladder cancer by the AFC-GBC-2009 Study Group.

    abstract:BACKGROUND:Incidental gallbladder cancer (GBC) is frequently discovered on the specimen when cholecystectomy for a benign disease is performed. The objective of the present study was to assess the management of incidental GBC patients in a French registry. METHODS:Data on patients with GBC treated between 1998 and 200...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-011-1134-3

    authors: Fuks D,Regimbeau JM,Le Treut YP,Bachellier P,Raventos A,Pruvot FR,Chiche L,Farges O

    更新日期:2011-08-01 00:00:00

  • Development and validation of a surgical workload measure: the surgery task load index (SURG-TLX).

    abstract:BACKGROUND:The purpose of the present study was to develop and validate a multidimensional, surgery-specific workload measure (the SURG-TLX), and to determine its utility in providing diagnostic information about the impact of various sources of stress on the perceived demands of trained surgical operators. As a wide r...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-011-1141-4

    authors: Wilson MR,Poolton JM,Malhotra N,Ngo K,Bright E,Masters RS

    更新日期:2011-09-01 00:00:00

  • Impact of recent advances in hepatobiliary imaging techniques on the preoperative diagnosis of carcinoma of the gallbladder.

    abstract::Among 26 patients with gallbladder carcinoma, 11 resected cases were studied retrospectively with respect to the preoperative imaging techniques and the operative procedures employed. Ultrasonography, endoscopic ultrasonography, and computed tomography were valuable in detecting gallbladder carcinoma preoperatively wh...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/BF01658723

    authors: Chijiiwa K,Sumiyoshi K,Nakayama F

    更新日期:1991-05-01 00:00:00

  • Ethical and Surgical Dilemmas in Patients with Neglected Surgical Diseases Visiting a Field Hospital in a Zone of Recent Disaster.

    abstract:OBJECT:The massive typhoon Haiyan (Yolanda) ripped across the central Philippines on November 8, 2013, and damaged infrastructure including hospitals. The Israeli Defense Forces field hospital was directed by the Philippine authorities to Bogo City in the northern part of the island of Cebu, to assist the damaged local...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-016-3692-x

    authors: Lin G,Marom T,Dagan D,Merin O

    更新日期:2017-02-01 00:00:00

  • Evaluation of office ultrasound usage among Australian and New Zealand breast surgeons.

    abstract:BACKGROUND:Surgeon performed ultrasound (US) is being increasingly embraced by breast surgeons worldwide as an integral part of patient assessment. The extent of its application within Australia and New Zealand is not well documented. The present study aimed to evaluate its current usage patterns and to determine suita...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-013-2076-8

    authors: Law MT,Kollias J,Bennett I

    更新日期:2013-09-01 00:00:00

  • Impact of Personal Protective Equipment on Surgical Performance During the COVID-19 Pandemic.

    abstract:BACKGROUND:The Severe Acute Respiratory Syndrome Coronavirus 2 pandemic has exposed surgeons to hazardous working conditions, imposing the need for personal protective equipment (PPE) use during surgery. The use of such equipment may affect their non-technical skills, augment fatigue, and affect performance. This study...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-020-05648-2

    authors: Yánez Benítez C,Güemes A,Aranda J,Ribeiro M,Ottolino P,Di Saverio S,Alexandrino H,Ponchietti L,Blas JL,International Cooperation Group on PPE and Emergency Surgery.,Ramos JP,Rangelova E,Muñoz M,Yánez C Sr

    更新日期:2020-09-01 00:00:00

  • Surgical Management of Iatrogenic Perforation of the Gastrointestinal Tract: 15 Years of Experience in a Single Center.

    abstract:BACKGROUND:Gastrointestinal (GI) tract perforation during endoscopy is a rare but severe complication. The aim of this study was to determine predictors of morbidity and mortality after iatrogenic endoscopic perforation. MATERIALS AND METHODS:All cases with iatrogenic endoscopic perforation receiving surgery at a tert...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-017-3986-7

    authors: Holmer C,Mallmann CA,Musch MA,Kreis ME,Gröne J

    更新日期:2017-08-01 00:00:00

  • Assessment of Capacity to Meet Lancet Commission on Global Surgery Indicators in the Federal Capital Territory, Abuja, Nigeria.

    abstract:BACKGROUND:This is a baseline assessment of surgical capacity in the Federal Capital Territory (FCT), in preparation for the creation of a National Surgical, Obstetric, Anesthesia, and Nursing Plan. METHODS:In October 2017, all 10 of the 11 secondary hospitals in FCT that provide surgical and/or obstetric care were su...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-018-4835-z

    authors: Anderson JE,Ndajiwo AB,Nuhu SA,Lawal OA,Amedu JO,Ameh EA

    更新日期:2019-03-01 00:00:00

  • Out-of-Pocket and Catastrophic Expenses Incurred by Seeking Pediatric and Adult Surgical Care at a Public, Tertiary Care Centre in Uganda.

    abstract:BACKGROUND:Surgical care is critical to establish effective healthcare systems in low- and middle-income countries, yet the unmet need for surgical conditions is as high as 65% in Ugandan children. Financial burden and geographical distance are common barriers to help-seeking in adult populations and are unmeasured in ...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-018-4691-x

    authors: MacKinnon N,St-Louis E,Yousef Y,Situma M,Poenaru D

    更新日期:2018-11-01 00:00:00

  • Effect of radiofrequency ablation of the liver on cell-mediated immunity in rats.

    abstract::We investigated the effect of radiofrequency ablation (RFA) of the liver on cell-mediated immunity in rats. Sprague-Dawley rats were divided into five groups: control group that did not have any procedure, a sham-operation group that underwent laparotomy, a lobectomy group that had left lateral lobectomy of the liver,...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-005-7728-x

    authors: Yu HC,Moon JI,Jin ZW,Lee DY,Kim CY,Song CH,Cho BH

    更新日期:2005-06-01 00:00:00

  • Correction to: Effectiveness of Topical Insulin Dressings in Management of Diabetic Foot Ulcers.

    abstract::In the original article, Mehreen K. Bhettani's last name and Mubarik Rehman's first name are misspelled. ...

    journal_title:World journal of surgery

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s00268-019-05334-y

    authors: Bhettani MK,Rehman M,Altaf HN,Altaf OS

    更新日期:2020-06-01 00:00:00

  • Intraoperative neuromonitoring does not reduce the incidence of recurrent laryngeal nerve palsy in thyroid reoperations: results of a retrospective comparative analysis.

    abstract:PURPOSE:Recurrent laryngeal nerve (RLN) palsy is the major concern of reoperative thyroid surgery, and the introduction of neuromonitoring could reduce the rate of this complication. The present study is a retrospective analysis of the experience with completion thyroidectomy with and without neuromonitoring in a refer...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-012-1548-6

    authors: Alesina PF,Rolfs T,Hommeltenberg S,Hinrichs J,Meier B,Mohmand W,Hofmeister S,Walz MK

    更新日期:2012-06-01 00:00:00

  • Clinicoanatomical study on the infraportal bile ducts of segment 3.

    abstract::In some patients, bile ducts of segments 2 and 3 (B2 and B3) run caudally to the umbilical portion of the left portal vein (UP)--an infraportal course. We aimed to evaluate the frequency and clinical implications of this variation. Between January 1992 and October 2000, 108 patients underwent resection for hilar chola...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-002-6544-9

    authors: Ozden I,Kamiya J,Nagino M,Uesaka K,Sano T,Nimura Y

    更新日期:2002-12-01 00:00:00

  • Long-Term Outcomes After Open Repair for Ruptured Abdominal Aortic Aneurysm.

    abstract:BACKGROUND:Early mortality in ruptured abdominal aneurysm (rAAA) is high, but data on long-term outcome are scarce. The aim of this study was to investigate the long-term outcome in survivors after open surgery for rAAA in well-defined population. METHODS:This is a population-based, observational long-term follow-up (...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-020-05457-7

    authors: Reite A,Søreide K,Kvaløy JT,Vetrhus M

    更新日期:2020-06-01 00:00:00

  • Malignant nonfunctioning endocrine tumors of the pancreas: predictive factors for survival after surgical treatment.

    abstract:BACKGROUND:There are scant studies that have analyzed the prognostic factors for malignant nonfunctioning endocrine tumors of the pancreas. We identified the predictive factors associated with long-term survival after surgical resection for malignant nonfunctioning endocrine tumors. METHODS:Among the 25 patients seen ...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-006-0585-4

    authors: Chung JC,Choi DW,Jo SH,Heo JS,Choi SH,Kim YI

    更新日期:2007-03-01 00:00:00

  • Early predictor of mortality due to irreversible posthepatectomy liver failure in patients with hepatocellular carcinoma.

    abstract:BACKGROUND:Although mortality after liver resection has declined, posthepatectomy liver failure (PHLF) remains a major cause of operative mortality. To date there is not consensus on a definition for PHLF. However, there have been many efforts to define PHLF causing operative mortality. In the present study we sought t...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-013-1959-z

    authors: Kim SH,Kang DR,Lee JG,Kim DY,Ahn SH,Han KH,Chon CY,Kim KS

    更新日期:2013-05-01 00:00:00

  • Quality of life of patients with inflammatory bowel disease after surgery.

    abstract::Quality of life is an important outcome measure following surgery for ulcerative colitis. Quality of life incorporates not only the physical or functional outcome; it also considers the emotional and social well-being of patients. Quality of life may be measured using disease-specific or generic quality of life measur...

    journal_title:World journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1007/s002689900400

    authors: McLeod RS,Baxter NN

    更新日期:1998-04-01 00:00:00

  • Outcomes research in surgery.

    abstract::The phrase "outcomes studies" is usually used to describe those studies where outcome is assessed in large cohorts of patients, often using data from administrative databases. They are used to determine the role and impact of variations in the structure and process of health care delivery play in routine practice. Opt...

    journal_title:World journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1007/s002689900651

    authors: Brenneman FD,Wright JG,Kennedy ED,McLeod RS

    更新日期:1999-12-01 00:00:00

  • Pancreatoduodenectomy in the treatment of chronic pancreatitis.

    abstract::The value of surgical resection for patients with chronic pancreatitis has been debated on account of persistent symptoms and the morbidity of the operative procedure, both immediate and delayed. This paper explores the consequence of pancreatoduodenectomy in 175 patients with chronic pancreatitis who were operated on...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-003-7239-6

    authors: Russell RC,Theis BA

    更新日期:2003-11-01 00:00:00

  • Key aspects of health policy development to improve surgical services in Uganda.

    abstract::Recently, surgical services have been gaining greater attention as an integral part of public health in low-income countries due to the significant volume and burden of surgical conditions, growing evidence of the cost-effectiveness of surgical intervention, and global disparities in surgical care. Nonetheless, there ...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-010-0585-2

    authors: Luboga S,Galukande M,Mabweijano J,Ozgediz D,Jayaraman S

    更新日期:2010-11-01 00:00:00

  • The optimal surgical treatment for primary hyperparathyroidism in MEN1 patients: a systematic review.

    abstract:BACKGROUND:The optimal surgical approach for patients with primary hyperparathyroidism (pHPT) and multiple endocrine neoplasia 1 (MEN1) is controversial. We sought to determine the optimal type of surgery for pHPT in MEN1. METHODS:We collected data on clinical presentation, surgery, and follow-up for MEN1 patients wit...

    journal_title:World journal of surgery

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00268-011-1068-9

    authors: Schreinemakers JM,Pieterman CR,Scholten A,Vriens MR,Valk GD,Rinkes IH

    更新日期:2011-09-01 00:00:00

  • The Importance of Abdominal Wall Closure After Definitive Surgery for Enterocutaneous Fistula.

    abstract:INTRODUCTION:The coexistence of an enterocutaneous fistula (ECF) with large abdominal wall defects represent one of the most demanding situations seen by a surgeon. Simultaneous treatment of ECF closure with abdominal wall defect closure has been widely debated. Our objective was to determine if the type of abdominal w...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-020-05635-7

    authors: Martinez JL,Souza-Gallardo LM,Ferat-Osorio E

    更新日期:2020-10-01 00:00:00

  • Segment III cholangiojejunostomy for carcinoma of the gallbladder.

    abstract::Jaundice in patients of advanced carcinoma of the gallbladder requires palliation for the distressing symptoms of pruritus and cholangitis. Intrahepatic segment III duct cholangiojejunostomy is a means for alleviating the obstruction with malignant porta block. The authors reviewed their experience with this procedure...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s002689900319

    authors: Chaudhary A,Dhar P,Tomey S,Sachdev A,Agarwal A

    更新日期:1997-10-01 00:00:00

  • Postoperative Adverse Events Inconsistently Improved by the World Health Organization Surgical Safety Checklist: A Systematic Literature Review of 25 Studies.

    abstract:BACKGROUND:The World Health Organization Surgical Safety Checklist (SSC) has been widely implemented in an effort to decrease surgical adverse events. METHOD:This systematic literature review examined the effects of the SSC on postoperative outcomes. The review included 25 studies: two randomised controlled trials, 13...

    journal_title:World journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1007/s00268-016-3519-9

    authors: de Jager E,McKenna C,Bartlett L,Gunnarsson R,Ho YH

    更新日期:2016-08-01 00:00:00

  • Gallstones and Bariatric Surgery: To Treat or Not to Treat?

    abstract:BACKGROUND:Obesity and rapid weight loss after bariatric surgery are risk factors for gallstone disease. OBJECTIVES:The present study sought to evaluate the feasibility of selective concomitant cholecystectomy only in patients with symptomatic disease and study risk factors for the development of symptomatic gallstone...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-016-3639-2

    authors: Morais M,Faria G,Preto J,Costa-Maia J

    更新日期:2016-12-01 00:00:00

  • Postoperative Elevation of the Neutrophil: Lymphocyte Ratio Predicts Complications Following Esophageal Resection.

    abstract:BACKGROUND:Complications following esophagectomy are a significant source of morbidity. The aim of this study was to investigate the utility of the neutrophil:lymphocyte ratio (NLR) in the early identification of complications following esophagectomy, as compared to other routinely available parameters. METHODS:We per...

    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-016-3427-z

    authors: Vulliamy P,McCluney S,Mukherjee S,Ashby L,Amalesh T

    更新日期:2016-06-01 00:00:00

  • 30-Day In-hospital Trauma Mortality in Four Urban University Hospitals Using an Indian Trauma Registry.

    abstract:INTRODUCTION:In India, half of the annual 200,000 road traffic deaths occur in hospitals, but the exact in-hospital trauma mortality rate remains unknown. A research consortium of universities, with a mandate to reduce trauma mortality, measured the baseline 30-day in-hospital mortality rate. METHODS:Between September...

    journal_title:World journal of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00268-016-3452-y

    authors: Roy N,Gerdin M,Ghosh S,Gupta A,Kumar V,Khajanchi M,Schneider EB,Gruen R,Tomson G,von Schreeb J

    更新日期:2016-06-01 00:00:00