Abstract:
BACKGROUND:Complications following esophagectomy are a significant source of morbidity. The aim of this study was to investigate the utility of the neutrophil:lymphocyte ratio (NLR) in the early identification of complications following esophagectomy, as compared to other routinely available parameters. METHODS:We performed a retrospective cohort study of patients undergoing Ivor-Lewis esophagectomy at a single centre. Baseline characteristics and complications occurring within the first 30 days of surgery were recorded. White blood cell counts and C-reactive protein (CRP) levels immediately following surgery (day 0) and over the subsequent three postoperative days were analysed. RESULTS:Sixty-five patients were included, of whom 29 (45 %) developed complications. The median NLR was similar among patients with and without a complicated recovery on day 0 (12.7 vs 13.6, p = 0.70) and day 1 (10.0 vs 9.3, p = 0.29). Patients who subsequently developed complications had a higher NLR on day 2 (11.8 vs 7.5, p < 0.001) and day 3 (9.0 vs 6.5, p = 0.001) compared to those whose recovery was uncomplicated. Receiver-operating-characteristic plots for the diagnostic performance of the NLR, neutrophil count, lymphocyte count and CRP level at each time point demonstrated that the NLR on day 2 had the greatest discriminatory ability in predicting complications, with an area under the curve of 0.83 (95 % CI 0.73-0.94). An NLR of >8.3 on day 2 had a sensitivity of 93 % and a specificity of 72 % for predicting complications. CONCLUSION:The NLR is a simple and routinely available parameter which has a high sensitivity in the early detection of complications following esophagectomy.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Vulliamy P,McCluney S,Mukherjee S,Ashby L,Amalesh Tdoi
10.1007/s00268-016-3427-zsubject
Has Abstractpub_date
2016-06-01 00:00:00pages
1397-403issue
6eissn
0364-2313issn
1432-2323pii
10.1007/s00268-016-3427-zjournal_volume
40pub_type
杂志文章abstract:BACKGROUND:Gastrointestinal (GI) tract perforation during endoscopy is a rare but severe complication. The aim of this study was to determine predictors of morbidity and mortality after iatrogenic endoscopic perforation. MATERIALS AND METHODS:All cases with iatrogenic endoscopic perforation receiving surgery at a tert...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-3986-7
更新日期:2017-08-01 00:00:00
abstract::Aerodigestive tract injuries in the neck are found in about 7% of penetrating neck injuries and are very rare in blunt trauma. A combination of a good physical examination with endoscopy and esophagography can reliably diagnose all significant injuries. Airway control in laryngotracheal trauma is the most urgent prior...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-001-0057-9
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:This study is intended to ascertain if outcome of acute abdominal surgery among elderly patients with acute abdominal pain have improved. METHODS:Altogether 456 patients aged >65 years underwent emergency abdominal surgery between the years 2007 and 2009 in our hospital. After excluding emergency reoperatio...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3207-1
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Strictures at the pharyngoesophageal junction represent a subgroup of corrosive esophageal strictures requiring a specialized management approach. Non-dilatable cricopharyngeal strictures need surgical intervention. We report the use of the sternocleidomastoid muscle myocutaneous inlay flap (SCMMIF) for reco...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9120-5
更新日期:2007-08-01 00:00:00
abstract::Malignant melanoma is notoriously resistant to chemotherapy. Standard single agents include dacarbazine and the nitrosoureas, but most series treating patients with metastatic melanoma report response rates of about 20%. Occasional patients, however, achieve long term remission, amounting to cure, after such treatment...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF02071532
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND:Billions of people worldwide lack access to safe affordable surgery. Surgical missions and non-governmental organisations (NGO) are vital in meeting this need, but long-term outcomes are rarely reported. Mercy Ships is a surgical NGO, and we aimed to measure disability-free survival, impact and patient satis...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3745-1
更新日期:2017-02-01 00:00:00
abstract::Percutaneous dilatational tracheostomy (PDT) is being increasingly used. Concerns have been raised as to its safety, especially when it is done at the bedside. A prospective evaluation was conducted of 100 consecutive, unselected critically ill patients with PDT. The mean intensive care unit (ICU) stay before PDT was ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002680010180
更新日期:2000-09-01 00:00:00
abstract::Treacher Collins Syndrome is a rare bilateral congenital deformity occurring in 1 in 10,000 births. It is also known, in the European literature, as Franceschetti Syndrome, and is additionally known as mandibulofacial dysostosis. It is a syndrome with a very wide spectrum of manifestations characterized by distortions...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01660753
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND:Surgical care is emerging as a crucial issue in global public health. Methodology is needed to assess the impact of surgical care from a public health perspective. METHODS:A consensus opinion of a group of surgeons, anesthesiologists, and public health experts was established regarding the methodology for e...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0261-6
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Chronic pilonidal disease is a debilitating condition that typically affects young adults. There is a wide variety of available therapeutic strategies reflecting the inconsistent outcomes attributed to the various operative approaches. The majority involve excision of the sinus tract followed by either prima...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1138-z
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:There is a consensus on the indication of laparoscopy-assisted distal gastrectomy (LADG) for early gastric cancer that needs D1 + alpha or D1 + beta lymph node dissection. However, many gastrointestinal surgeons consider D2 lymph node dissection in LADG to be difficult, therefore, only a few medical institut...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9697-3
更新日期:2008-11-01 00:00:00
abstract::Mass screening for the purpose of detecting thyroid cancer at its earliest stage may not be recommended at the present time, but screening focused on certain risk groups is advocated. Familial nonmedullary thyroid carcinoma (FNMTC) is a distinct clinical entity with a high incidence of multifocality and association wi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7676-x
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Diabetes mellitus (DM) is a known risk factor for worse outcomes after emergency abdominal surgery (EAS). However, it is unclear if the type of diabetes treatment (insulin or oral agents) has any effect on outcomes after EAS. METHODS:Matched cohort study utilizing the ACS NSQIP database. Patients with DM un...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3469-2
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Primary hyperparathyroidism (PHPT) is a common endocrine disorder that predominantly affects patients >60 and is increasing in prevalence. Identifying risk factors for poor outcomes after parathyroidectomy in older adults will help tailor operative decision making. The impact of frailty on surgical outcomes ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4629-3
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:There have been no reports on the impact of preoperative biliary MRSA infection on the outcome of major hepatectomy. The aim of this study was to review the surgical outcome of patients who underwent hepatobiliary resection after biliary drainage and to evaluate the impact of preoperative biliary MRSA infect...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-0990-1
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Routine preoperative staging in pancreas cancer is controversial. We sought to evaluate the rates of diagnostic laparoscopy (DLAP) for pancreatic cancer. METHODS:We queried the National Surgical Quality Improvement Program for patients with pancreas cancer (2005-2013) and compared groups who underwent DLAP,...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4855-8
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:The use of pulmonary artery catheter (PAC) is controversial. The purpose of this study was to document the changing pattern of PAC use and to determine its effect on outcome. METHODS:The use of PAC was analyzed in patients ≥16 years old admitted to the surgical intensive care unit (SICU) over a 9-year period...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1149-9
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Surgical disease burden falls disproportionately on individuals in low- and middle-income countries. These populations are also the least likely to have access to surgical care. Understanding the barriers to access in these populations is therefore necessary to meet the global surgical need. METHODS:Using g...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3765-x
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Conflicting findings have been reported concerning the survival of patients treated with limb salvage and amputation for osteosarcoma. This study aimed to identify predictors associated with surgery types and survival difference. METHODS:Patients with osteosarcoma were selected from the Surveillance Epidemi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05471-9
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:The Severe Acute Respiratory Syndrome Coronavirus 2 pandemic has exposed surgeons to hazardous working conditions, imposing the need for personal protective equipment (PPE) use during surgery. The use of such equipment may affect their non-technical skills, augment fatigue, and affect performance. This study...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05648-2
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:To assess the survival outcomes among a contemporary cohort of colorectal cancer patients with isolated synchronous liver or lung metastases treated with or without surgical resection of the metastases. METHODS:Surveillance, epidemiology and end results database has been accessed and cases with isolated live...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05353-9
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Whilst injuries are a major cause of disability and death worldwide, a large proportion of people in low- and middle-income countries lack timely access to injury care. Barriers to accessing care from the point of injury to return to function have not been delineated. METHODS:A two-day workshop was held in ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05571-6
更新日期:2020-09-01 00:00:00
abstract::Distinguishing cellular follicular adenomas (FA) from minimally invasive follicular carcinomas (FC) continues to plague even experienced thyroid pathologists. DNA ploidy analysis has been promoted as a means of making this differentiation; however, the finding of DNA aneuploidy in FA has caused concern that they may d...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01658504
更新日期:1990-05-01 00:00:00
abstract::Medical errors from communication failures are enormous during the perioperative period of cardiac surgical patients. As caregivers change shifts or surgical patients change location within the hospital, key information is lost or misconstrued. After a baseline cognitive study of information need and caregiver workflo...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0319-5
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:The World Health Organization Surgical Safety Checklist (SSC) has been widely implemented in an effort to decrease surgical adverse events. METHOD:This systematic literature review examined the effects of the SSC on postoperative outcomes. The review included 25 studies: two randomised controlled trials, 13...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-016-3519-9
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Breast cancer in young women is uncommon, but when it does occur it has been reported to have aggressive biological characteristics. The incidence of breast cancer peaks at age 40 in Hong Kong Chinese women, earlier than in Caucasians. This study is the first to report the tumor characteristics and managemen...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9589-6
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Medullary thyroid carcinoma (MTC) originates from calcitonin-producing cells of the thyroid. In 2009, we published our first report on the biological characteristics and prognosis of 118 MTC patients. Herein, we enrolled a larger number of patients with longer follow-up periods to further study the biologica...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4738-z
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:The evolution of diagnostic procedures has resulted in an increase in early detection of pathologically T1 (pT1) colorectal cancer (CRC). However, the risk factors affecting long-term outcomes of patients with pT1 CRCs have been unclear. The aim of the present study was to identify risk factors for postopera...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1378-y
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Selective nonoperative management (SNOM) of penetrating neck injuries (PNI) has steadily gained favor, but indications for surgery and adjunctive diagnostic studies remain debated. The purpose of the present study is to validate a protocol of SNOM of PNI based on physical examination, which further dictates ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9766-7
更新日期:2008-12-01 00:00:00
abstract::The success of parathyroid surgery is determined by the identification and removal of all parathyroid tumors. Parathyroid tumors accumulate and retain 2-methoxyisobutylisonitrile (MIBI) labeled with technetium-99m. Intravenous injection of this radiopharmacon prior to parathyroid surgery allows identification of parat...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s002689900427
更新日期:1998-06-01 00:00:00