Abstract:
:We investigated the effect of radiofrequency ablation (RFA) of the liver on cell-mediated immunity in rats. Sprague-Dawley rats were divided into five groups: control group that did not have any procedure, a sham-operation group that underwent laparotomy, a lobectomy group that had left lateral lobectomy of the liver, a one-lobe RFA group that had RFA on the left lateral lobe of the liver, and a two-lobe RFA group that had RFA on the left lateral and left median lobe of the liver. Delayed-type hypersensitivity (DTH) was induced by challenging the ears of previously sensitized rats with 2,4-dinitro-1-fluorobenzene. Cell-mediated immunity was evaluated by direct measurement of the ear thickness and quantitative analysis of leukocytic infiltration of the tissue. The increased ear thickness was 42.0%, 69.2%, 61.8%, 46.7%, and 39.8% from the baseline one day after each procedure, and the mean leukocytic infiltration into the ear tissue was 3136.7, 3895.0, 3913.3, 2803.3, and 2316.7/mm(2) seven days after each procedure in the control, sham-operation, lobectomy, one-lobe RFA, and two-lobe RFA groups, respectively. In conclusion, RFA of the liver tissue can partially abolish the augmentation of DTH and leukocytic infiltration those were seen in the hepatic lobectomy and sham-operation groups. The procedure had a negative effect on cell-mediated immunity in rats, and the intensity of RFA showed a reverse correlation with cell-mediated immunity.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Yu HC,Moon JI,Jin ZW,Lee DY,Kim CY,Song CH,Cho BHdoi
10.1007/s00268-005-7728-xkeywords:
subject
Has Abstractpub_date
2005-06-01 00:00:00pages
739-43issue
6eissn
0364-2313issn
1432-2323journal_volume
29pub_type
杂志文章abstract::The development of laparoscopic surgery has provided minimally invasive surgeons with advanced laparoscopic instrumentation and high definition imaging. The resulting surgical expertise and technology has now been extended to gastric endoluminal surgery. Laboratory and clinical investigations have been initiated for v...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/pl00012311
更新日期:1999-04-01 00:00:00
abstract::The effect of a treatment versus controls may be expressed in relative or absolute terms. For rational decision-making, absolute measures are more meaningful. The number needed to treat, the reciprocal of the absolute risk reduction, is a powerful estimate of the effect of a treatment. It is particularly useful becaus...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7916-8
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:The aim of this work was to study the impact of anemia on surgical outcomes and the impact of instituting appropriate workup and treatment of anemia on surgical outcomes. METHODS:We conducted a case-control retrospective chart review of all hernia repair, hydrocele repair, and hysterectomy cases at the SEAR...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1615-z
更新日期:2012-09-01 00:00:00
abstract::Despite careful selection of cirrhotic patients with hepatocellular carcinoma (HCC), liver resection remains associated with a greater risk than in patients without underlying liver disease. In this study we assessed by multivariate analysis parameters associated with in-hospital mortality and morbidity in a selected ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/pl00012259
更新日期:1997-05-01 00:00:00
abstract::Eighty patients undergoing cholecystectomy were either assigned deliberately (n = 30) or randomized (n = 50) to drainage (n = 38) or nondrainage (n = 42). Subhepatic collections were seen on ultrasonography (US) after 48 to 72 hours in 12 of 35 patients with drainage and 24 of 42 patients without drainage (p < 0.05). ...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01655718
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Efficient DNA damage repair by MutL-homolog DNA mismatch repair (MMR) enzymes, MLH1, MLH3, PMS1 and PMS2, are required to maintain thyrocyte genomic integrity. We hypothesized that persistent oxidative stress and consequent transcriptional dysregulation observed in thyroid follicles will lead to MMR deficien...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4299-6
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Lymph node metastasis is important when evaluating the prognosis of patients with differentiated thyroid cancer (DTC). However, the current N-staging system cannot fully reflect the clinical significance of cervical lymph node metastasis in DTC. In this study, we employed Surveillance, Epidemiology, and End ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4343-6
更新日期:2018-06-01 00:00:00
abstract::The effects of splenectomy in 41 patients managed from 1982 to 1995 at Sher-i-Kashmir Institute of Medical Sciences, Srinagar (Jammu and Kashmir), India, were studied. Immune thrombocytopenic purpura (ITP) was the main indication for therapeutic splenectomy among all the hematologic disorders. The mean age was 30 year...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689910017
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Surgical disease burden falls disproportionately on individuals in low- and middle-income countries. These populations are also the least likely to have access to surgical care. Understanding the barriers to access in these populations is therefore necessary to meet the global surgical need. METHODS:Using g...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3765-x
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Midgut malrotation most commonly presents in young children. This diagnosis is not often entertained in the adolescent or adult with abdominal complaints. We reviewed our experience with this subset of malrotation patients. METHODS:A retrospective review of medical records from adolescent or adult patients ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9490-3
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:The role of lymphadenectomy in adrenocortical carcinoma resection is controversial. Therefore, we conducted a population-based study to assess the association between positive lymph nodes (LN) and survival. METHODS:The Surveillance, Epidemiology, and End Results set of cancer registries were utilized. The a...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05801-x
更新日期:2021-01-01 00:00:00
abstract::Knowledge of how factors related to esophageal cancer resection affect long-term quality of life after surgery is scarce, and no population-based studies are available. Therefore, we conducted a Swedish nationwide, prospective, population-based study of how esophageal surgery-related factors influence quality of life ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7887-9
更新日期:2005-07-01 00:00:00
abstract::Two-hundred and fifty patients undergoing initial exploration for primary hyperparathyroidism were analyzed for differences in clinical presentation, biochemical status, pathology, and outcome of surgery. In patients less than 60 years of age (younger patients, n = 119) the most common preoperative symptoms and signs ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF02067389
更新日期:1992-07-01 00:00:00
abstract::The management of metastatic neuroendocrine tumors incorporates multimodal therapy with surgery, biotherapy, and chemotherapy. Tumor-targeted therapies using radiolabeled octreotide and metaiodobenzylguanidine (mIBG) represent a novel treatment approach. The aim of this study was to evaluate the effectiveness of 131I-...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7603-1
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Video-assisted thoracoscopic surgery (VATS) is a new area of exploration and evolution in thoracic minimal invasive surgery. The uniportal VATS approach has become popular during lung resection for small nodules and ground glass lesions. Our objective is to investigate the efficacy, availability and safety o...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05781-y
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Recent studies have shown a 7-15% lymph node (LN) metastasis rate in submucosal invasive colorectal cancer (SICC). Identifying risk factors for LN metastasis is crucial in selecting therapeutic modalities for SICC. We assessed the possibility of and the risk factors for LN metastasis in SICC. METHODS:We per...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9628-3
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Papillary thyroid carcinoma (PTC) frequently recurs to the lymph nodes, which may not be fatal immediately but is a stressor for physicians and patients. Recurrence to the distant organs, although less frequent, is often life-threatening, and the lung and bone are organs to which PTC is likely to recur. In t...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1423-5
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:The Institute of Medicine has identified atrial fibrillation (AF) among national priorities for research. We examine the incidence of AF and its association with outcomes of patients undergoing abdominal surgery. METHODS:Patients ≥ 55 years who underwent abdominal surgery captured in a State Inpatient Datab...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2777-7
更新日期:2015-01-01 00:00:00
abstract::Subfascial elimination of incompetent perforating veins is the most effective therapeutic principle in the treatment of trophic skin disorders associated with varicosis. A recently developed endoscopic technique allows accurate sectioning of perforating veins with direct observation of the veins and minor trauma. From...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02067007
更新日期:1992-09-01 00:00:00
abstract::In the Surgical Department of the University of Erlangen, 307 reconstructions in all areas of the arterial tree were performed with PTFE (GORE-TEX) grafts, of which 188 were performed in the femoral-popliteal and femoral-crural areas. Femoral-popliteal bypass grafts above the knee joint remained patent in 93% of the p...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02393582
更新日期:1980-01-01 00:00:00
abstract::We determined the relative value of the metastatic colorectal cancer doubling time as a predictor of recurrence and survival after hepatectomy in comparison with other established predictors. Consecutive patients who underwent hepatic resection ( n = 144) for colorectal cancer liver metastases were studied retrospecti...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-7088-3
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:Appendiceal neuroendocrine tumors (aNET) are a common entity in routine medical care, with a rate per appendectomy as high as 0.3-0.9 %. Considering the relatively young age at diagnosis for these patients, exact information about the long-term prognosis of aNET is required. Survival rates vary substantially...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3164-8
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Obesity and rapid weight loss after bariatric surgery are risk factors for gallstone disease. OBJECTIVES:The present study sought to evaluate the feasibility of selective concomitant cholecystectomy only in patients with symptomatic disease and study risk factors for the development of symptomatic gallstone...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3639-2
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Accurate presurgical assessment is important to anticipate postoperative complications, especially in the growing proportion of elderly cancer patients. We designed a study to define which comorbid conditions at the time of diagnosis predict complications after surgery for colorectal cancer. PATIENTS:A rand...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0711-8
更新日期:2007-01-01 00:00:00
abstract::Radiation-induced proctitis with hemorrhage is not a common complication of radiotherapy to the pelvis for carcinoma. In the most severe forms, massive hemorrhage may necessitate repeated transfusions and inpatient treatment. In severe cases medical treatment has not been proved effective. Surgery may lead to serious ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900166
更新日期:1996-10-01 00:00:00
abstract::We reviewed our experience with 34 patients with metastatic endocrine tumors (METs) who were treated by different modalities. Eight patients were treated by chemotherapy or chemoembolization because of stable disease or surgical contraindications. Seventeen patients underwent curative or cytoreductive surgical resecti...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900138
更新日期:1996-09-01 00:00:00
abstract::Neoadjuvant therapy for locally advanced breast cancer improves disease control, but the complications of treatment are not well established. The aim of this study was to assess the operative morbidity in 20 consecutive patients with locally advanced, noninflammatory breast cancer treated with preoperative chemotherap...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01658934
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:The goal of the present study was to critically review and identify the strength of available evidence in the literature on the use of laparoscopic appendectomy (LA) in complicated appendicitis (CA). METHODS:The Cochrane Library and Controlled Trials Registry, MEDLINE (Ovid), PubMed, Web of knowledge, and S...
journal_title:World journal of surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00268-010-0669-z
更新日期:2010-09-01 00:00:00
abstract::In a retrospective study the clinical course of 40 patients with symptomatic persistent or recurrent parathyroid cancer was analyzed in order to assess the value of aggressive surgical intervention. Recurrence was diagnosed after a median period of 33 months (1-228 months). Twenty-two patients had locoregional disease...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF00353773
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:Open surgical cricopharyngeal myotomy(CM) is considered standard of care for Zenker's diverticulum(ZD). Trans-oral CM has been described using a rigid stapling device for two decades; however, this remains problematic for severely kyphotic patients. This problem can be overcome with flexible endoscopy utiliz...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3442-0
更新日期:2016-06-01 00:00:00