Application of formaldehyde for treatment of hemorrhagic radiation-induced proctitis.

Abstract:

:Radiation-induced proctitis with hemorrhage is not a common complication of radiotherapy to the pelvis for carcinoma. In the most severe forms, massive hemorrhage may necessitate repeated transfusions and inpatient treatment. In severe cases medical treatment has not been proved effective. Surgery may lead to serious complications and is technically difficult. Six patients who showed a hemorrhagic radiation-induced proctitis have been treated as outpatients with application of formaldehyde 4%. In four cases the bleeding ceased after the first formaldehyde application; two patients continued to bleed, but another application of formaldehyde 3 weeks later definitively controlled the hemorrhage. Follow-up evaluation at 12 months showed in each case that the hemorrhage was controlled and treated. There were no complications, such as burns or late stenoses of the deep layers of the rectum. This inexpensive technique is well tolerated by the patient, gives good long-term results, and is available at every hospital. Local application of formaldehyde 4% to the rectum may be the treatment of choice for hemorrhagic radiation-induced proctitis.

journal_name

World J Surg

journal_title

World journal of surgery

authors

Roche B,Chautems R,Marti MC

doi

10.1007/s002689900166

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

1092-4; discussion 1094-5

issue

8

eissn

0364-2313

issn

1432-2323

journal_volume

20

pub_type

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