Abstract:
:Radiologically demonstrable pancreatic endocrine tumors are a frequent requirement for exploration in patients with multiple endocrine neoplasia type I (MEN-I). Such delayed intervention is accompanied by a 30% to 50% incidence of pancreatic endocrine metastases. This study explores biochemical tumor markers and operative findings in relation to preoperative pancreatic radiology in 25 MEN-I patients. They underwent pancreatic surgery with (n = 19) or without (n = 6) radiologic signs of primary tumor and absence of metastases upon conventional examination, including OctreoScan testing (n = 10). Biochemical diagnosis required an increasing elevation of at least two independent pancreatic tumor markers. Tumor diameters averaged 1.1 cm (0-5 cm) and 0.9 cm (0.2-1.5 cm) in the patients with and without positive preoperative radiology, respectively. These investigations never displayed more than one of the consistently multiple tumors, and the results were falsely positive in 26%. Preoperatively unidentified regional or hepatic metastases were found at surgical exploration in 26% of patients with radiologic localization and in none of the others. Limited pancreatic tumor involvement necessitated intraoperative absence of metastases and pancreatic lesions = 1 cm in diameter on palpation, intraoperative ultrasonography, and microscopy. It occurred in 37% and 50% of the patients with and without radiologic tumor localization, respectively. The number of positive tumor markers was similar for patients with limited and major disease (2.3 vs. 2.7), whereas four or more such markers were found in all those with malignancies. The mean marker level was higher in patients with radiologically demonstrable tumors and lower in those with limited disease, but with a substantial overlap. OctreoScan testing was negative in all cases with limited disease and was the single most sensitive method (75%) in the others. Limited pancreatic disease could not be identified preoperatively, and the present means of biochemical pancreatic tumor identification invariably involved the presence of at least one lesion >/= 7 mm in diameter. Conventional pancreatic imaging is insensitive and nonspecific for recognizing even substantial pancreatic tumors associated with MEN-I.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Skogseid B,Oberg K,Akerström G,Eriksson B,Westlin JE,Janson ET,Eklöf H,Elvin A,Juhlin C,Rastad Jdoi
10.1007/s002689900451subject
Has Abstractpub_date
1998-07-01 00:00:00pages
673-7; discussion 667-8issue
7eissn
0364-2313issn
1432-2323journal_volume
22pub_type
杂志文章abstract:BACKGROUND:Neurosurgical capacity is extremely deficient in East African countries where 27 neurosurgeons serve more than 250 million people. To build capacity, the Duke University Medical Center and New Mulago Hospital in Uganda applied a two-pronged twinning approach that placed usable surplus equipment in a developi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1080-0
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Roux-en-Y anastomosis is the standard of care for biliary reconstruction. Yet, a direct bilio-biliary anastomosis preserves the normal sphincter mechanism and endoscopic access to the biliary tree for diagnostic and therapeutic purposes. Duct-to-duct biliary reconstruction is widely used in liver transplanta...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1318-x
更新日期:2012-01-01 00:00:00
abstract::The aim of this study was to determine if fat absorption is better after pylorus-preserving pancreatoduodenectomy (PPPD) or duodenum-preserving pancreatic head resection (DPPHR) compared with that following pancreatoduodenectomy with gastrectomy (SPD), provided the patients have similar pancreatic exocrine function. F...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900156
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND:Perioperative blood transfusion has been shown to be associated with poor outcome in various types of malignancy. However, the relationship between the amount of blood loss and specific types of cancer recurrence has not been documented. METHODS:We retrospectively examined the amount of intraoperative blood...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-9979-4
更新日期:2009-06-01 00:00:00
abstract:INTRODUCTION:The follicular variant of papillary thyroid carcinoma (FVPTC) is the most common histologic subtype of papillary thyroid carcinoma (PTC). However, it is still controversial whether FVPTC should behave differently from classical PTC (CPTC). The present study aimed at evaluating any potential difference in c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0356-7
更新日期:2006-05-01 00:00:00
abstract::There has been a long, unresolved debate regarding the operation of choice for well differentiated carcinoma of the thyroid. We therefore analyzed the feasibility, scope, sample size, and length of follow-up required to determine the optimal operation for papillary thyroid carcinoma. A statistical approach was used to...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900016
更新日期:1996-01-01 00:00:00
abstract::The appropriate role for additional radiotherapy in patients with resectable rectal cancer is not yet settled. Irradiation has been considered by surgeons and radiotherapists as superfluous since no effect on survival has been shown. However, numerous trials have demonstrated that peri-operative radiotherapy decreases...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF02066982
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:Surgical site infection (SSI) is a common cause of major morbidity after liver resection. This study aimed to identify the risk factors for incisional and organ/space SSIs after liver resection. METHODS:Our liver surgery database was retrospectively analyzed for patients treated between January 2009 and Nov...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2922-3
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Inguinal hernia is thought to be common in rural Ghana, though no recent data exist on hernia prevalence in the country. This information is needed to guide policy and increase access to safe hernia repair in Ghana and other low-resource settings. METHODS:Adult men randomly selected from the Barekese sub-di...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3335-7
更新日期:2016-04-01 00:00:00
abstract:INTRODUCTION:Acute intestinal ischemia is in most cases a lethal condition with a low survival rate. Risk factors of perioperative mortality are poorly defined. The aim of this study was to define risk factors that predict an adverse outcome of acute mesenteric ischemia (AMI). METHODS:A total of 132 consecutive patien...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0560-5
更新日期:2006-08-01 00:00:00
abstract::The surgical morbidity, mortality, and effectiveness of a modified nonshunting operation that includes splenic artery division instead of splenectomy, devascularization, and esophageal transection (SAD group) were evaluated. Eighteen cirrhotic patients with varices who underwent this modified procedure were compared w...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF00299180
更新日期:1995-05-01 00:00:00
abstract::The clinicopathological characteristics relevant to prognosis after surgical treatment of intrahepatic cholangiocarcinoma (ICC) remain unclear. In this study, the clinicopathological features of 19 patients with mass-forming ICC, the most common form of the disease, were reviewed to analyze prognostic determinants. Tw...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0291-1
更新日期:2002-06-01 00:00:00
abstract::Parathyroid carcinoma is a rare cause of primary hyperparathyroidism. However, to our best knowledge, at least 163 cases of functioning parathyroid carcinoma appeared in the English literature from 1981 to 1989. We summarize the available information obtained from the reports of those patients and compare it with prev...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01665308
更新日期:1991-11-01 00:00:00
abstract:BACKGROUND:It is generally believed that the accompanying conditions in patients with inflammatory bowel disease (IBD) are associated with a high incidence of surgical site infection (SSI), and sometimes these patients are classified as compromised hosts without definitive clinical evidence. The aim of this study was t...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-9934-4
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Critical illness disproportionately affects people in low-income countries (LICs). Efforts to improve critical care in LICs must account for differences in demographics and infrastructure compared to high-income settings. Part of this effort includes the development and validation of intensive care unit (ICU...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05078-9
更新日期:2019-10-01 00:00:00
abstract::In some patients, bile ducts of segments 2 and 3 (B2 and B3) run caudally to the umbilical portion of the left portal vein (UP)--an infraportal course. We aimed to evaluate the frequency and clinical implications of this variation. Between January 1992 and October 2000, 108 patients underwent resection for hilar chola...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6544-9
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:The prognosis of advanced hepatocellular carcinoma (HCC) remains poor, particularly in patients with tumor thrombi (TT) in the major vessels. PATIENTS AND METHODS:From July 1992 to October 2004, 161 patients diagnosed as having advanced HCC with major vascular involvement were seen consecutively at our hosp...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0250-3
更新日期:2006-03-01 00:00:00
abstract::Secretin is a stimulator of both endocrine and exocrine secretions of the pancreas, and we aimed to evaluate its effects on splanchnic blood flow in rats with a microsphere technique. Anesthetized rats were infused with secretin (0.5 or 2.0 micrograms/kg body weight/hr) for 10 minutes. Some animals were normoglycemic,...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0037-0
更新日期:2001-07-01 00:00:00
abstract::The aim of this study was to evaluate prognostic factors after the recurrence of hepatocellular carcinoma (HCC) in patients who had undergone hepatic resection. We used univariate and multivariate retrospective analyses of 29 clinicopathologic factors in 143 patients with recurrent HCC. Patients were classified into f...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7205-y
更新日期:2004-07-01 00:00:00
abstract::This article presents an analysis of acute gastroduodenal mucosal lesions (AGML) based on a review of current literature and the personal experience of the authors. The pathology of AGML involes two distinct types of lesions, namely, superficial erosions confined to the acid-secreting gastric mucosa and presenting as ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01654729
更新日期:1977-01-01 00:00:00
abstract::The current clinical applications of ultrasonography (US) of soft tissue masses are discussed. These include the detection of occult masses, the characterization of palpable masses, tumor surveillance, and US guided percutaneous aspirations/biopsies of soft tissue masses. ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689910036
更新日期:2000-02-01 00:00:00
abstract:OBJECT:The massive typhoon Haiyan (Yolanda) ripped across the central Philippines on November 8, 2013, and damaged infrastructure including hospitals. The Israeli Defense Forces field hospital was directed by the Philippine authorities to Bogo City in the northern part of the island of Cebu, to assist the damaged local...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3692-x
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the factors for considering surgery on thyroid nodules that had non-diagnostic results on two consecutive cytology examinations. METHODS:A total of 104 thyroid nodules with two consecutive non-diagnostic cytology examinations in 104 patients were investigated. Nodule...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1397-8
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Chagas disease is a serious public health issue in South and Central America due to its high prevalence, morbidity, and mortality. The esophageal form of the disease leads to achalasia and consequent megaesophagus. In advanced or recurrent cases of megaesophagus, there is no consensus for which of three esta...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2445-3
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:The prognosis of Fournier's gangrene (FG) depends on early diagnosis and management. In this study, our objective was to identify the distinct features of FG that may influence the clinical outcome. METHODS:A retrospective chart review was performed in patients with a diagnosis of FG between January 1999 and...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0777-3
更新日期:2006-09-01 00:00:00
abstract::The aim of this study was to clarify the role of ganglion cells in the development and recurrence of sigmoid volvulus. We analyzed 9 samples obtained from 9 patients who had undergone sigmoidectomy for sigmoid volvulus, and, for comparison, 18 samples from 18 patients who had undergone sigmoidectomy or low anterior re...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7462-9
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Right hepatectomy with caudate lobectomy (RHx) is considered an appropriate procedure for Bismuth type I/II perihilar cholangiocarcinoma in terms of its anatomical and oncological aspect. However, validity of left hepatectomy with caudate lobectomy (LHx) concomitant with arterial resection and reconstruction...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4833-1
更新日期:2019-03-01 00:00:00
abstract::In spite of recent therapeutic advances, severe overt secondary hyperparathyroidism due to chronic renal failure necessitates parathyroidectomy and recurrent hyperparathyroidism is one of the most significant problems in this patient population. In the present study, the incidence of recurrent hyperparathyroidism was ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02067331
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:The importance of safe anesthesia for the best possible surgical outcomes in every patient is not disputed in high resource settings. Low-income countries lag far behind in the provision of, and training for, safe anesthesia practice. Too little is known about numbers and types of providers in a majority of ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2775-9
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:Gastroesophageal reflux disease is common in Western societies, although the prevalence of reflux symptoms in the community is not well described. In this study we determined the prevalence of symptoms of gastroesophageal reflux and other "esophageal" symptoms, and the consumption of medication for reflux ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9780-9
更新日期:2009-01-01 00:00:00