Abstract:
:The clinicopathological characteristics relevant to prognosis after surgical treatment of intrahepatic cholangiocarcinoma (ICC) remain unclear. In this study, the clinicopathological features of 19 patients with mass-forming ICC, the most common form of the disease, were reviewed to analyze prognostic determinants. Two or more segmentectomies of the liver with systematic lymphadenectomy were performed in 18 patients. Resection of the extrahepatic bile duct was performed in 14 patients, and reconstruction of the portal vein was accomplished in 5 patients. Stage IVA or IVB tumors were seen in 13 patients, and lymph node (LN) metastasis was present in 14 patients. The estimated 5-year survival rate after surgery for mass-forming ICC was 28%, with median survival time of 18 months. In univariate analysis, five variables were determined to be significantly correlated with poor survival of patients with mass-forming ICC after surgery. These variables include mass-forming ICC with periductal infiltration, perineural invasion, portal vein invasion, presence of intrahepatic metastasis, and two or more LN metastases. Survival rates of 5 patients without LN metastasis and 6 patients with a single LN metastasis were 80% and 33% at 5 years, respectively, while 8 patients with two or more LN metastasis failed to survive beyond 2 years. Multivariate analysis revealed the presence of intrahepatic metastasis to be an independent prognostic factor of poor survival. Hepatectomy with resection of the extrahepatic bile duct and systematic lymphadenectomy yields a good chance for prolonged survival for patients with mass-forming ICC when the lesion is singular and LN metastasis is limited to a regional LN. Because the presence of intrahepatic metastasis was closely related to a poor prognosis in patients with mass-forming ICC, efficacious chemotherapy would be needed to control development of the lesion.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Suzuki S,Sakaguchi T,Yokoi Y,Okamoto K,Kurachi K,Tsuchiya Y,Okumura T,Konno H,Baba S,Nakamura Sdoi
10.1007/s00268-001-0291-1keywords:
subject
Has Abstractpub_date
2002-06-01 00:00:00pages
687-93issue
6eissn
0364-2313issn
1432-2323journal_volume
26pub_type
杂志文章abstract:BACKGROUND:Pheochromocytoma with synchronous ipsilateral adrenal cortical adenoma (PSCA) may present with mixed clinical, biochemical, and radiological features characteristic to each neoplasm subtype. METHODS:All patients with a pathological diagnosis of pheochromocytoma were evaluated for an ipsilateral cortical ade...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4110-8
更新日期:2017-12-01 00:00:00
abstract::Radiation-induced proctitis with hemorrhage is not a common complication of radiotherapy to the pelvis for carcinoma. In the most severe forms, massive hemorrhage may necessitate repeated transfusions and inpatient treatment. In severe cases medical treatment has not been proved effective. Surgery may lead to serious ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900166
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND:Surgical treatment of amiodarone-associated thyrotoxicosis (AAT) is effective although fewer than 100 cases have been reported world wide. MATERIALS AND METHODS:We reviewed 14 patients treated with total thyroidectomy by a single surgeon from 1998 to 2005. RESULTS:There were 11 male and 3 female patients w...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-005-0673-x
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:The use of pulmonary artery catheter (PAC) is controversial. The purpose of this study was to document the changing pattern of PAC use and to determine its effect on outcome. METHODS:The use of PAC was analyzed in patients ≥16 years old admitted to the surgical intensive care unit (SICU) over a 9-year period...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1149-9
更新日期:2011-08-01 00:00:00
abstract::Local recurrence in differentiated and medullary thyroid carcinoma develops frequently from metastatic infiltration of cervical lymph nodes. Despite an aggressive surgical approach, postoperative calcitonin levels as biochemical evidence for residual cancer cells remain often elevated in patients with medullary thyroi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0197-y
更新日期:2002-02-01 00:00:00
abstract::Surgical exposure of the recurrent laryngeal nerve decreases the incidence of nerve injuries during thyroid surgery. Intraoperative neuromonitoring was introduced to facilitate identification and protection of the recurrent laryngeal nerve. Between February 1996 and June 2002 a total of 288 patients underwent thyroid ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7226-6
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:The histone deacetylase (HDAC) inhibitors have emerged as the useful reagents that epigenetically modulate the expression of various genes. In the present study, the effects of HDAC inhibitors on the expression of inflammation-related genes and lung injury during sepsis were investigated. METHODS:Mice were ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0493-5
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Closure of loop ileostomy can be safely performed using sutures or staplers. The aim of the present study was to compare the cost effectiveness of three different techniques. METHODS:A total of 128 consecutive patients who underwent closure of loop ileostomy between January 2002 and December 2008 were analy...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0787-7
更新日期:2010-12-01 00:00:00
abstract::Persistent pain after hernia repair is common, although it is usually mild. In 3% of patients it is severe, however, and has significant effects on work and social activities. The purpose of this review was to examine factors that affect pain after hernia repair. Although the type of anaesthetic used, local or general...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-005-7903-0
更新日期:2005-08-01 00:00:00
abstract::The phrase "outcomes studies" is usually used to describe those studies where outcome is assessed in large cohorts of patients, often using data from administrative databases. They are used to determine the role and impact of variations in the structure and process of health care delivery play in routine practice. Opt...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900651
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to assess the safety and feasibility of performing robot-assisted pediatric surgery using the da Vinci Surgical System in a variety of surgical procedures. METHODS:A retrospective review of 144 robot-assisted pediatric surgical procedures performed in our institution between Ju...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0431-6
更新日期:2010-05-01 00:00:00
abstract::Malnutrition in its various forms is without doubt the commonest disease. Acute malnutrition resulting from a total lack of ingestion clearly shows that not only are water and electrolytes a priority for survival but also energy reserves. It also shows that the maximum wasting that the lean body mass can withstand is ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/pl00012343
更新日期:1999-06-01 00:00:00
abstract::Surgical oncology is one of the most frequently studied surgical specialties with regard to disparities in quality of care. There is variation in the care received according to nonclinical factors such as age, race and ethnicity, education, income, and even geographic region. Differences exist with regard to who gets ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9383-x
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Papillary thyroid carcinoma (PTC) frequently recurs to the lymph nodes, which may not be fatal immediately but is a stressor for physicians and patients. Recurrence to the distant organs, although less frequent, is often life-threatening, and the lung and bone are organs to which PTC is likely to recur. In t...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1423-5
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:The survival impact of distal pancreatectomy (DP) with celiac axis resection for locally advanced pancreatic body/tail cancer remains unclear. METHODS:A total of 16 patients underwent DP with celiac axis resection, while 76 underwent standard DP for pancreatic body/tail cancer. The indications for DP with c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3670-3
更新日期:2017-01-01 00:00:00
abstract::Transsphenoidal pituitary surgery has radically modified the management of pituitary-dependent hypercortisolism (Cushing's disease). Bilateral adrenalectomy may, however, represent the ultimate treatment in some cases of hypercortisolism. In the present study we report our experience of bilateral adrenalectomy in 82 p...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900118
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:The present study was designed to evaluate the impact of the tyrosine kinase ligands VEGF-A/C/D, PDGF-A/B on tumor dissemination and survival in gastric cancer. This is the first study analyzing all these parameters in a homogeneous patient population undergoing surgery. METHODS:The expression pattern of VE...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1041-7
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:We reported phonatory recovery in the majority of 88 patients after recurrent laryngeal nerve (RLN) reconstruction. Here we analyzed factors that might influence the recovery, in a larger patient series. METHODS:At Kuma Hospital, 449 patients (354 females and 95 males) underwent RLN reconstruction with dire...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3634-7
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Stapled anopexia was introduced as a surgical method in 1993. Long-term data with special interest in functional results and relapse symptoms are rarely presented. Urinary discomfort and problems with fecal urge incontinence are addressed as severe side effects. We present our long-term results (using data f...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9818-z
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Unilateral vocal fold paralysis (UVFP) may present as an uncommon complication of extralaryngeal neoplasms, requiring diagnostic scrutiny to seek occult tumors or diseases. The aim of this study was to examine the utility of computed tomography (CT) in evaluating adult UVFP of unknown etiology. METHODS:From...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-1991-z
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Utilization of breast reconstruction (BR) is low in many jurisdictions. We studied the geographical and surgical workforce factors that contribute to access and use of BR using a small area analysis approach with a geographical unit of analysis. METHODS:We linked administrative data from Ontario Canada to c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3060-2
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Anastomotic leakage is a serious clinical problem after colorectal resections and is associated with a significantly increased length of stay, morbidity and mortality. The aim of the present study was to evaluate the effect of changes in clinical practice on anastomotic leakage rate after colorectal resectio...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4423-7
更新日期:2018-07-01 00:00:00
abstract::Surgical resection is the treatment of choice for patients with stage I and stage II non-small-cell lung cancer (NSCLC--squamous cell, adenocarcinoma, and large-cell carcinoma). Distant recurrence is an important cause of death after complete surgical resection, occurring in 30-60% of patients. Postoperative adjuvant ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01659083
更新日期:1993-11-01 00:00:00
abstract:PURPOSE:Recurrent laryngeal nerve (RLN) palsy is the major concern of reoperative thyroid surgery, and the introduction of neuromonitoring could reduce the rate of this complication. The present study is a retrospective analysis of the experience with completion thyroidectomy with and without neuromonitoring in a refer...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1548-6
更新日期:2012-06-01 00:00:00
abstract::Hepatoblastoma is a rare pediatric malignancy that frequently appears in an advanced unresectable stage. Improved resectability and survival rate have been reported with the help of neoadjuvant chemotherapy. Between January 1987 and June 1995 a series of 20 patients were managed with a diagnosis of hepatoblastoma. The...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002680020052
更新日期:2001-02-01 00:00:00
abstract::Congenital diaphragmatic hernia (CDH) is one of the most common causes of neonatal morbidity and mortality. The clinical spectrum of CDH ranges from minimally affected infants who do well with modern neonatal care to severely affected infants who die despite all interventions. Two decades of research have led to advan...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-002-6739-0
更新日期:2003-01-01 00:00:00
abstract::Mesosigmoidoplasty is a nonresective procedure for nongangrenous sigmoid volvulus. It aims to correct the main pathogenetic factor of this condition, the narrow but long mesosigmoid. Although it had been demonstrated by intraoperative measurements that this has indeed achieved its purpose, recurrent volvulus has been ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-7010-z
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Vibrio vulnificus infection can progress rapidly in skin or soft tissue, and it is potentially life-threatening. The purpose of the present study was to explore the predictors of mortality in patients with V. vulnificus infections of skin or soft tissue. METHODS:The medical records of 119 consecutive patien...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0455-y
更新日期:2010-07-01 00:00:00
abstract:INTRODUCTION:Preventing secondary insult to the brain is imperative following traumatic brain injury (TBI). Although TBI does not preclude nonoperative management (NOM) of splenic injuries, development of hypotension in this setting may be detrimental and could therefore lead trauma surgeons to a lower threshold for op...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4494-0
更新日期:2018-08-01 00:00:00
abstract::The purpose of this study was to evaluate the pattern of recovery of intestinal motility using manometric and clinical assessment in the postoperative ileus following abdominal surgery. We reviewed the charts of 18 patients who underwent partial colectomy for colon cancer (group A, without vagotomy) and compared them ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900310
更新日期:1997-10-01 00:00:00