Abstract:
:The appropriate role for additional radiotherapy in patients with resectable rectal cancer is not yet settled. Irradiation has been considered by surgeons and radiotherapists as superfluous since no effect on survival has been shown. However, numerous trials have demonstrated that peri-operative radiotherapy decreases an often high local recurrence rate while others believe it has a definite place in routine management. Several surgeons have, on the contrary, claimed that a skilled surgeon compared to a less skilled surgeon, will get the same acceptably low local recurrence rates. Since we will probably never have a randomized trial comparing "good" and "bad" surgeons, this argument cannot be settled. A further obstacle arises in the difficulty of persuading surgeons to organize their routine work so that it is performed in an optimal way by those specializing in this field. The question also arises whether radiotherapy should be delivered pre-operatively, postoperatively or as a "sandwich" technique, i.e., both pre-operatively and postoperatively. According to radio-biological considerations and results from reported trials, the best effect on local tumor control has been achieved using pre-operative radiotherapy.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Påhlman L,Glimelius Bdoi
10.1007/BF02066982keywords:
subject
Has Abstractpub_date
1992-09-01 00:00:00pages
858-65issue
5eissn
0364-2313issn
1432-2323journal_volume
16pub_type
杂志文章,评审abstract:BACKGROUND:The aim of this study was to evaluate the therapeutic efficacy of two surgical procedures used to treat middle thoracic esophageal squamous cell carcinoma and compare the results. METHODS:A total of 167 patients with middle thoracic esophageal squamous cell carcinoma were included in the study, including 10...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0341-7
更新日期:2010-02-01 00:00:00
abstract::Left untreated, aneurysmal disease of the abdominal aorta is a highly lethal condition. Standard transabdominal repair of aortic aneurysm, although successful and durable, continues to be plagued by significant morbidity, mortality, and cost. Placement of an endovascular graft through a femoral arteriotomy is a new te...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900101
更新日期:1996-07-01 00:00:00
abstract::The surgical treatment of groin hernias continues to undergo technical modifications. The introduction of minimally invasive surgery had added a possible new dimension, replacing an inguinal approach by laparoscopy. Conceived some 15 years ago, the thesis was subjected to a clinical trial where coincidental abdominal ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01655704
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Although ultrasonographic (US) evaluation is currently recommended for the workup of all palpable thyroid nodules, little guidance exists regarding the manner in which US data are to be used. Herein, we examine the available evidence and recommend how US can be used most effectively to predict malignancy. We...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-008-9494-z
更新日期:2008-07-01 00:00:00
abstract:INTRODUCTION:The role for diverting ostomy as a method to help reduce morbidity and mortality has been well established in the combat trauma population. However, factors that influence the type of ostomy used and which ostomies become permanent are poorly studied. We examine patterns of ostomy usage and reversal in a l...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4759-7
更新日期:2019-01-01 00:00:00
abstract:AIM:To evaluate the application value of a three-dimensional (3D) printing model in the training of choledochoscopy techniques. MATERIALS AND METHODS:Imaging data from two patients with biliary dilatation were used to produce two 3D reconstruction models which were subsequently constructed into 3D printing models (No....
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-018-4731-6
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:The use of pulmonary artery catheter (PAC) is controversial. The purpose of this study was to document the changing pattern of PAC use and to determine its effect on outcome. METHODS:The use of PAC was analyzed in patients ≥16 years old admitted to the surgical intensive care unit (SICU) over a 9-year period...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1149-9
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Enhanced recovery (ERAS) guidelines do not differentiate between left- and right-sided colectomies, but differences in recovery have been reported for the two procedure types. We aimed to compare compliance with the ERAS protocol and outcomes after right versus left colectomy. METHODS:Between June 2011 and ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3563-5
更新日期:2016-10-01 00:00:00
abstract::Subfascial elimination of incompetent perforating veins is the most effective therapeutic principle in the treatment of trophic skin disorders associated with varicosis. A recently developed endoscopic technique allows accurate sectioning of perforating veins with direct observation of the veins and minor trauma. From...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02067007
更新日期:1992-09-01 00:00:00
abstract:INTRODUCTION TO THE PROBLEM:Though declining in the recent decades, high-energy musculoskeletal trauma remains a major contributor to the burden of disease in high-income countries (HICs). However, due to limitations in the available body of the literature, evaluation of this burden is challenging. The purpose of this ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-018-4742-3
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:The purpose of the present study was to analyze the risk multi-factors of postoperative cardiac arrhythmia for elderly patients with esophageal or cardiac carcinoma. METHODS:A total of 756 operations for elderly patients (>65 years of age) with esophageal or cardiac carcinoma were performed in our departmen...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0222-0
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Traditional perioperative care for colonic surgery in elderly patients is associated with increased morbidity and mortality compared to that of younger patients. Although multimodal perioperative rehabilitation has evolved as a valid concept to improve postoperative outcome, its use has not yet been establis...
journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s00268-009-0018-2
更新日期:2009-08-01 00:00:00
abstract::Although a number of histologic and treatment factors that individually and in combination predict for an increased risk of local recurrence after breast conserving surgery can be identified, none so obviously compromises survival that breast conservation is contraindicated because that risk factor is present. In-brea...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00348195
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Finnmark County is the northernmost county in Norway. For several decades, the rate of mortality after injury in this sparsely inhabited region has remained above the national average. Following documentation of this discrepancy for the period 1991-1995, improvements to the trauma system were implemented. Th...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1102-y
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Exact tissue identification during parathyroidectomy is essential to successfully cure hyperparathyroidism. PTH level determination from tissue aspirates has been advocated as a "biochemical frozen section" for parathyroid tissue identification. We investigated the sensitivity and specificity of this method ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0351-5
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Thymic epithelial tumors are characterized by slow growth and variable malignant behavior. We present our experience on the surgical management of these tumors. MATERIALS AND METHODS:We conducted a retrospective analysis of patients with thymomas undergoing modified maximal thymectomy over a period of 16 ye...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0097-0
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:To evaluate whether the preoperative magnetic resonance angiography (MRA) can predict the risk of cerebral ischemia associated with the carotid endarterectomy (CEA). METHODS:Between January 2004 and December 2010, 382 consecutive patients (mean age: 56.6 years; range: 45-78 years) were identified to have un...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1851-2
更新日期:2013-03-01 00:00:00
abstract::The geographic distribution of duodenal ulcer and its characteristics in rural areas of high incidence in developing countries are reviewed. The choice of surgical procedures is discussed in light of the bulky diet and nutritional problems of these countries. A vagotomy procedure is advised for duodenal ulcer and a B...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01654731
更新日期:1977-01-01 00:00:00
abstract::Surgical education in the United Kingdom has evolved to meet the need of the National Health Service (NHS) for a relatively small body of consultants practicing autonomously and carrying ultimate clinical responsibility for their patients. This form of specialist practice is markedly different from that found in most ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00298916
更新日期:1994-09-01 00:00:00
abstract::Patients with short bowel syndrome (SBS) receiving total parenteral nutrition (TPN) have a high incidence of catheter-related sepsis, one of its major complications. The aim of this study was to correlate the length of remaining small bowel (RSB) with septic episodes related to the central venous catheter in a group o...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002680010274
更新日期:2000-12-01 00:00:00
abstract::The purpose of this study was to evaluate the surgical outcome of completion thyroidectomy in patients with presumed unilateral well-differentiated thyroid cancer (WDTC). The medical records of all patients having had unilateral thyroid lobectomy for WDTC, who subsequently underwent completion thyroidectomy, were revi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02067365
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:The objective of this study was to determine whether rat insulin promoter (RIP) could, in a mouse model, direct expression of an adenovirus-mediated reporter gene specifically into pancreatic islets via systemic delivery. METHODS:Five hundred and eight base pairs of the RIP DNA sequence were constructed int...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0688-3
更新日期:2006-08-01 00:00:00
abstract::The goal of fluid resuscitation in the burn patient is maintenance of vital organ function at the least immediate or delayed physiological cost. To optimize fluid resuscitation in severely burned patients, the amount of fluid should be just enough to maintain vital organ function without producing iatrogenic pathologi...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF02067109
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:This study evaluated the impact of tumor regression grading (TRG) and other pathologic variates in a cohort of rectal carcinoma patients treated with neoadjuvant chemoradiotherapy (CRT). The value of a grading less than pCR for predicting survival is unknown. Tumor budding has not been systematically studied...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1409-8
更新日期:2012-03-01 00:00:00
abstract::There are three basic roles of laparoscopic surgery for patients with colorectal cancer. First, although infrequently needed prior to therapy, diagnostic or staging laparoscopy may be valuable in certain colorectal cancer patients. Second, the laparoscopic approach may offer several attractive features for the palliat...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900294
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:This prospective, non-randomized, comparative study evaluated morbidity of chemotherapy administration via a totally implantable venous access device (TIVAD) versus peripheral intravenous access (PIVA), and satisfaction in breast cancer patients in a limited-resource setting. METHODS:Consecutive patients re...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2378-x
更新日期:2014-05-01 00:00:00
abstract::The lack of sufficient suitable human donor lungs for the many patients requiring pulmonary transplantation as life-saving therapy for end-stage lung diseases has generated extensive interest in cross-species lung transplantation. Ethical concerns and those of animal rights advocates have prompted studies of nonprimat...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900332
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the feasibility of digital defog technique in 3D laparoscopic surgery for right colon cancer. METHODS:Fifty patients with right colon cancer were divided into digital defogging group and control group. The intraoperative image clarity, the surgeon's anxiety, the time ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4402-z
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to evaluate the efficacy of 10 % sucralfate ointment in the reduction of acute postoperative pain after open hemorrhoidectomy. METHODS:A total of 48 patients (24 men and 24 women) between 20 and 70 years of age who underwent open hemorrhoidectomy were included in this prospe...
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-012-1805-8
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:A precise understanding of anastomotic recurrence (AR) permits efficient surveillance and treatment strategies. This study aimed to evaluate the clinicopathologic characteristics of patients with AR undergoing curative resection for colorectal cancer (CRC), compare colonic with rectal tumors and investigate ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3663-2
更新日期:2017-01-01 00:00:00