Abstract：
BACKGROUND:The aim of the present study was to evaluate the efficacy of 10 % sucralfate ointment in the reduction of acute postoperative pain after open hemorrhoidectomy. METHODS:A total of 48 patients (24 men and 24 women) between 20 and 70 years of age who underwent open hemorrhoidectomy were included in this prospective, double-blind, randomized, controlled trial and were randomly divided into two groups (24 in each group), receiving either sucralfate ointment or placebo immediately after surgery and then every 12 h for 14 days. The primary outcome measure was pain intensity measured by a visual analogue scale at different time points after hemorrhoidectomy. RESULTS:The sucralfate group had significantly less pain than the placebo group at 24th h and the 48th h after hemorrhoidectomy (4 ± 1.14 vs 5.08 ± 0.97; P = 0.001 and 3 ± 0.72 vs 4.41 ± 0.8; P < 0.001, respectively), and they consumed lower amounts of analgesics at the same time intervals (12.50 ± 16.48 vs 21.87 ± 15.30 mg of pethidine; P = 0.047 and 152 ± 23 vs 172 ± 29 mg of diclofenac; P = 0.009, respectively). The same trend continued until the end of the trial. CONCLUSIONS:Sucralfate ointment reduced the acute postoperative pain after hemorrhoidectomy.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Ala S,Saeedi M,Eshghi F,Rafati M,Hejazi V,Hadianamrei Rdoi
10.1007/s00268-012-1805-8subject
Has Abstractpub_date
2013-01-01 00:00:00pages
233-8issue
1eissn
0364-2313issn
1432-2323journal_volume
37pub_type
杂志文章,随机对照试验abstract：BACKGROUND:Organ shortage is the greatest challenge facing the field of organ transplantation today. Use of more organs of marginal quality has been advocated to address the shortage. METHOD:We examined the pattern of donation and organ use in the United States as shown in the Organ Procurement and Transplantation Net...
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