Risk factors and management of local recurrence following breast conservation surgery.

Abstract:

:Although a number of histologic and treatment factors that individually and in combination predict for an increased risk of local recurrence after breast conserving surgery can be identified, none so obviously compromises survival that breast conservation is contraindicated because that risk factor is present. In-breast recurrence is associated with the risk of any disease remaining after lumpectomy if the breast is not irradiated and the risk of large amounts of residual disease if irradiation is used. Some risk factors appear to predict for both local recurrence and distant recurrence, whereas others predict an increased risk of local recurrence but appear to have little effect on the risk of metastatic disease. Overall, the relation between in-breast recurrence and the risk of systemic metastases is poorly understood. Furthermore, the efficacy of chemotherapy in decreasing the risk of systemic metastases after in-breast recurrence has not been evaluated. Mastectomy is the treatment of choice for in-breast recurrence after breast conserving surgery and radiation therapy. A few patients are candidates for a second attempt at breast conservation.

journal_name

World J Surg

journal_title

World journal of surgery

authors

Osteen RT

doi

10.1007/BF00348195

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

76-80

issue

1

eissn

0364-2313

issn

1432-2323

journal_volume

18

pub_type

杂志文章,评审
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    pub_type: 杂志文章,随机对照试验

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    pub_type: 杂志文章,评审

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    pub_type: 杂志文章

    doi:10.1007/BF00353773

    authors: Sandelin K,Tullgren O,Farnebo LO

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  • Clinical Significance of Multiple Pulmonary Metastasectomy for Hepatocellular Carcinoma.

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