Abstract：
BACKGROUND:The lung is the most common site of extrahepatic metastasis from hepatocellular carcinoma (HCC). The aim of this study was to evaluate the significance and long-term outcomes of pulmonary metastasectomy for HCC, especially in patients with multiple nodules or repeated pulmonary recurrence. METHODS:We retrospectively analyzed 19 patients who underwent pulmonary metastasectomy for HCC at our institution from 1993 to 2013. RESULTS:No in-hospital mortality occurred. The 19 patients included 14 men. The median age was 61 (range 20-76) years. Eight patients (42 %) had single pulmonary metastatic lesions, whereas 4 (21 %) had >10 lesions. Median follow-up after pulmonary metastasectomy was 23.1 (6.3-230) months. Twelve patients died, and the cause of death was HCC progression in nine. The 1-, 3-, 5-, and 10-year overall survival rates after pulmonary metastasectomy were 89, 48, 48, and 21 %, respectively. Seven patients developed pulmonary recurrence after initial pulmonary metastasectomy. Five of the seven underwent repeat metastasectomy, with a median survival time of 65 months, and 2- and 3-year survival rates of 100 and 67 %, respectively. The 2- and 3-year survival rates in the four patients with >10 pulmonary nodules were 75 and 50 %, respectively. CONCLUSIONS:Surgical resection is a safe and effective treatment in selected patients with pulmonary metastasis from HCC, even in those with multiple nodules. Repeated locoregional therapy for lung recurrence might help to improve survival in these patients.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Mizuguchi S,Nishiyama N,Izumi N,Tsukioka T,Komatsu H,Iwata T,Tanaka S,Takemura S,Kubo Sdoi
10.1007/s00268-015-3213-3subject
Has Abstractpub_date
2016-02-01 00:00:00pages
380-7issue
2eissn
0364-2313issn
1432-2323pii
10.1007/s00268-015-3213-3journal_volume
40pub_type
杂志文章abstract：BACKGROUND:Solitary fibrous tumor of the pleura (SFTP) represents a clinical entity rarely encountered, especially in giant forms. Complete surgical resection for giant tumor of pleura is a challenge. The aim of this article is to present five new cases of giant SFTP, and to discuss their clinical characteristics and t...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0715-x
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:The efficacy and the indications of resection of synchronous or metachronous hepatic and pulmonary metastases from colorectal cancer (CRC) are controversial. This study retrospectively reviewed the cases of CRC patients who underwent both liver and lung resection to define the appropriate indications for sur...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1708-8
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:The goal of this study was to evaluate the outcome of patients who had the Nuss procedure for repair of pectus excavatum. METHODS:Thirty-nine patients (26 male, 13 female) of 61 (63.9%) who had bar removal after the Nuss procedure agreed to participate in an interview. All patients and their parents were as...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1111-x
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:The aim of the present study was to investigate the incidence of sleep disturbance and insomnia in patients with primary hyperparathyroidism (PHPT), and to evaluate the effect of parathyroidectomy. METHODS:A questionnaire was prospectively administered to adult patients with PHPT who underwent curative para...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s00268-013-2285-1
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:The splintering of general surgery into subspecialties in the past decade has brought into question the relevance of a continued emphasis on traditional general surgical training. With the majority of trainees now expressing a preference to subspecialise early, this study sought to identify if the requiremen...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2890-7
更新日期：2015-02-01 00:00:00
abstract：:Factors responsible for recurrence of esophageal cancer were investigated in 90 patients who underwent extended radical esophagectomy with three-field dissection for a squamous cell carcinoma in the thoracic esophagus. The initial tumor recurrence was grouped as either locoregional (site of the primary tumor, anastomo...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900228
更新日期：1997-03-01 00:00:00
abstract：BACKGROUND:The purpose of the present study was to analyze the risk multi-factors of postoperative cardiac arrhythmia for elderly patients with esophageal or cardiac carcinoma. METHODS:A total of 756 operations for elderly patients (>65 years of age) with esophageal or cardiac carcinoma were performed in our departmen...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0222-0
更新日期：2009-12-01 00:00:00
abstract：:The role of the tumor suppressor gene p53 and proto-oncogenes mdm-2, waf-1,and bcl-2 in sporadic colorectal carcinoma (CRC) has been well investigated. However, little is known about the role of these genes in the development of ulcerative colitis-associated colorectal carcinoma (CAC). Colectomy specimens from patient...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0237-7
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND:It has been reported that the paraesophagogastric devascularization with esophageal transection procedure, also known as the modified Sugiura procedure, was effective in the treatment of variceal bleeding. However, it was not widely accepted by other surgeons because of the high rate of rebleeding, complicat...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2478-2
更新日期：2014-08-01 00:00:00
abstract：:Central pancreatectomy is an uncommonly performed procedure that may be particularly useful for the removal of benign and low malignant potential lesions in the neck and body of the pancreas. This procedure may have fewer major complications and better preserve endocrine and exocrine function than the more commonly pe...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-6848-4
更新日期：2003-05-01 00:00:00
abstract：BACKGROUND:Total thyroidectomy is now accepted worldwide as the standard surgical procedure for the management of benign bilateral nodular thyroid disease. Hypocalcemia is the most common complication of that procedure and a variety of strategies for diagnosing and managing post-thyroidectomy hypocalcemia have been adv...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-008-9545-5
更新日期：2008-07-01 00:00:00
abstract：:Pepsinogen C is a proteolytic enzyme involved in the digestion of proteins in the stomach; it is also synthesized by a significant percentage of female breast carcinomas. In addition, it has been demonstrated that pepsinogen C is one of the few proteins induced by androgens in breast carcinoma cells. Here we evaluate ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/pl00012325
更新日期：1999-05-01 00:00:00
abstract：BACKGROUND:The incidence, pattern, and severity of sleep disturbance and cognitive dysfunction has not been well characterized for patients with primary hyperparathyroidism (PHPT). There is no agreement on the mechanism of the development or resolution of such symptoms, and in no previous study has cerebral activity be...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0361-x
更新日期：2006-05-01 00:00:00
abstract：:Duodenal leiomyomas are rare neoplasms and when present are usually asymptomatic. There are, however, isolated case reports of such leiomyomas giving rise to complications including gastrointestinal hemorrhage and obstruction. The purpose of this study was to review the surgical experience with duodenal leiomyomas at ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002680020083
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:Connective tissue growth factor (CTGF) expression changes variously in different human malignancies. The role of CTGF in hepatocellular carcinoma (HCC) is still not clear. The purpose of this study was to investigate the role of serum CTGF in patients with HCC and its correlation with HCC angiogenesis. METH...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0648-4
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:Management of anal fistula represents a balance between curing the condition and maintaining anal continence. Recent reports of the results of the porcine anal fistula plug have demonstrated excellent fistula healing rates without reporting significant complications. METHODS:The outcome of patients who underwe...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9504-1
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Billions of people worldwide lack access to safe affordable surgery. Surgical missions and non-governmental organisations (NGO) are vital in meeting this need, but long-term outcomes are rarely reported. Mercy Ships is a surgical NGO, and we aimed to measure disability-free survival, impact and patient satis...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3745-1
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:A lower-pitched voice is one of the most common voice alterations after thyroidectomy without laryngeal nerve injury. The aim of this study was to evaluate the acoustic and stroboscopic changes and the treatment outcomes in patients with a lower-pitched voice with the goal of eventually establishing a therap...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2062-1
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Closure of loop ileostomy can be safely performed using sutures or staplers. The aim of the present study was to compare the cost effectiveness of three different techniques. METHODS:A total of 128 consecutive patients who underwent closure of loop ileostomy between January 2002 and December 2008 were analy...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0787-7
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:Diverticulitis is commonly diagnosed using ultrasound (US), followed by computed tomography (CT). Our aim was to determine the diagnostic accuracy of US compared with CT for patients with uncomplicated and complicated diverticulitis. METHODS:We reviewed medical records of 232 patients admitted with divertic...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2423-9
更新日期：2014-07-01 00:00:00
abstract：:Enteral nutrition (EN) and total parenteral nutrition (TPN) may provide life-sustaining therapy for surgical patients. The duration of nutritional therapy (enteral or parenteral) implies distinct access routes. We review the main aspects related to access routes for nutrient delivery. The enteral route, whenever feasi...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002680010264
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND:There is emerging evidence indicating that distractions in the operating room (OR) are prevalent. Studies have shown a negative impact of distractions, but they have been conducted mostly with residents in simulated environments. We tested the hypothesis that intraoperative distractions are associated with d...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2315-z
更新日期：2014-04-01 00:00:00
abstract：:Acute biliary pancreatitis is a serious complication of biliary calculous disease and is associated with significant morbidity and mortality. The role of endoscopic retrograde cholangiopancreatography (ERCP) in the management of acute biliary pancreatitis has been the focus of discussion in recent years. In addition, ...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s002689900207
更新日期：1997-02-01 00:00:00
abstract：BACKGROUND:Tumor size has been advocated as possible risk factors for occult central lymph node metastases (CNM) in papillary thyroid carcinoma (PTC) patients. This prospective study evaluated factors that could identify patients at higher risk of occult CNM, especially comparing micro-PTC and macro-PTC. METHODS:One h...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4390-z
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND:Recent studies have shown a 7-15% lymph node (LN) metastasis rate in submucosal invasive colorectal cancer (SICC). Identifying risk factors for LN metastasis is crucial in selecting therapeutic modalities for SICC. We assessed the possibility of and the risk factors for LN metastasis in SICC. METHODS:We per...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9628-3
更新日期：2008-09-01 00:00:00
abstract：:The clinicopathological characteristics relevant to prognosis after surgical treatment of intrahepatic cholangiocarcinoma (ICC) remain unclear. In this study, the clinicopathological features of 19 patients with mass-forming ICC, the most common form of the disease, were reviewed to analyze prognostic determinants. Tw...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0291-1
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:Recurrent renal hyperparathyroidism (HPT) is a serious problem after parathyroidectomy (PTx). We evaluated the frequency of graft-dependent recurrent HPT and the clinical outcomes after removal of the autograft. METHODS:Between March 1980 and January 2009, 2660 patients underwent total PTx with forearm auto...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0412-9
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND:Surgical site infection (SSI) is a common cause of major morbidity after liver resection. This study aimed to identify the risk factors for incisional and organ/space SSIs after liver resection. METHODS:Our liver surgery database was retrospectively analyzed for patients treated between January 2009 and Nov...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2922-3
更新日期：2015-05-01 00:00:00
abstract：:The evaluation of screening programs for cancer is considered. Initial evaluation has to be in terms of mortality, but increasing importance should be attached to measures which evaluate the interaction of early detection with the disease process. These include the degree to which diagnosis is advanced, both in time a...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01671147
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:The recent development and spread of ultrasonography and ultrasonography-guided fine needle aspiration biopsy (FNAB) has facilitated the detection of small papillary microcarcinomas of the thyroid measuring 1 cm or less (PMC). The marked difference in prevalence between clinical thyroid carcinoma and PMC det...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0303-0
更新日期：2010-01-01 00:00:00
